While it is nice to have some amount of confidence that my data is safe from prying eyes in the case of loss or theft of my laptop, this setup poses a number of significant inconveniences:
1. Backup images of the encrypted operating system can only be restored to the original hard drive (ie.: the drive that has failed). So, recovery from this failure requires the time-consuming process of re-installing the OS, re-installing my software and re-encrypting it. Upgrading the hard drive where both the old and new drives are still functional is not much better as it requires decryption, copying the partition(s) and re-encryption.
2. With the data being stored in large file containers, each around 100-200GB. It can be come quite burdensome to deal with these huge files all the time. It's also a particularly volatile situation, as the file container is functionally useless if it's not completely intact.
3. As much as I'd like to use this situation as an opportunity to upgrade to an SSD, use with OTFE is said to pose risks of data leaks, cause decreased performance and premature failure due to excessive write operations.
So, with that, I'm open to suggestions for alternatives. Do you use encryption for your hard drive(s)? What's your setup like and how manageable is it?