Ostracus writes "Researches at the University of Washington have recently developed a system, which for the first time, offers an instantly customizable approach to user interfaces. Each participant in the program is placed through a brief skills test and then a mathematically-based version of the user interface optimized for his or her vision and motor abilities is generated. The current off-the-shelf designs are especially discouraging for the disabled, the elderly and others who have trouble controlling a mouse, because most computer programs have standardized button sizes, fonts, and layouts, which are designed for normal users." Link to Original Source
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