Science

'Ghost' That Haunts South Carolina Rail Line May Be Caused By Tiny Earthquakes (science.org) 37

sciencehabit shares a report from Science: Legend has it that if you walk along Old Light Road in Summerville, South Carolina, you might see an eerie glow hovering over an abandoned rail line in the nearby woods. Old-timers will tell you it's a spectral lantern held by the apparition of a woman searching for her decapitated husband's head. Susan Hough has proposed a scientific explanation that is far more plausible, however. A seismologist with the U.S. Geological Survey, she believes the so-called Summerville Light could represent a rare natural phenomenon: earthquake lights.

Sparks from steel rail tracks could ignite radon or other gases released from the ground by seismic shaking, Hough explains in an interview with Science. In Summerville, I think it's the railroad tracks that matter. I've crawled around tracks during my fieldwork in South Carolina. Historically, when [rail companies] replaced tracks, they didn't always haul the old track away. So, you've got heaps of steel out there. Sparks might be part of the story. And maybe the railroads are important for another reason. They may naturally follow fault lines that have carved corridors through the landscape.
The findings have been published in the journal Seismological Research Letters. Hough also cites a paper published by Japanese scientist Yuji Enomoto that connects earthquake lights to the release of gases like radon or methane.
Earth

Atomic Scientists Adjust 'Doomsday Clock' Closer Than Ever To Midnight (reuters.com) 162

The Bulletin of Atomic Scientists moved their Doomsday Clock to 89 seconds before midnight on Tuesday, the closest to catastrophe in the timepiece's 78-year history. The Chicago-based group cited Russia's nuclear threats during its Ukraine invasion, growing tensions in the Middle East, China's military pressure near Taiwan, and the rapid advancement of AI as key factors. The symbolic clock, created in 1947 by scientists including Albert Einstein, moved one second closer than last year's setting.
Social Networks

Peeing Is Socially Contagious In Chimps (404media.co) 56

After observing 20 chimpanzees for over 600 hours, researchers in Japan found that chimps are more likely to urinate after witnessing others do so. "[T]he team meticulously recorded the number and timing of 'urination events' along with the relative distances between 'the urinator and potential followers,'" writes 404 Media's Becky Ferreira. "The results revealed that urination is, in fact, socially contagious for chimps and that low-dominant individuals were especially likely to pee after watching others pee. Call it: pee-r pressure." The findings have been published in the journal Cell Biology. From the study: The decision to urinate involves a complex combination of both physiological and social considerations. However, the social dimensions of urination remain largely unexplored. More specifically, aligning urination in time (i.e. synchrony) and the triggering of urination by observing similar behavior in others (i.e. social contagion) are thought to occur in humans across different cultures (Figure S1A), and possibly also in non-human animals. However, neither has been scientifically quantified in any species.

Contagious urination, like other forms of behavioral and emotional state matching, may have important implications in establishing and maintaining social cohesion, in addition to potential roles in preparation for collective departure (i.e. voiding before long-distance travel) and territorial scent-marking (i.e. coordination of chemosensory signals). Here, we report socially contagious urination in chimpanzees, one of our closest relatives, as measured through all-occurrence recording of 20 captive chimpanzees across >600 hours. Our results suggest that socially contagious urination may be an overlooked, and potentially widespread, facet of social behavior.

In conclusion, we find that in captive chimpanzees the act of urination is socially contagious. Further, low-dominance individuals had higher rates of contagion. We found no evidence that this phenomenon is moderated by dyadic affiliation. It remains possible that latent individual factors associated with low dominance status (e.g. vigilance and attentional bias, stress levels, personality traits) might shape the contagion of urination, or alternatively that there are true dominance-driven effects. In any case, our results raise several new and important questions around contagious urination across species, from ethology to psychology to endocrinology. [...]

Medicine

The Cancer That Doctors Don't Want to Call Cancer (wsj.com) 87

A growing number of doctors are advocating to rename low-grade prostate cancer to reduce unnecessary aggressive treatments that can lead to debilitating side effects. About one-quarter of men diagnosed with prostate cancer have the lowest-risk form, yet studies show 40% opt for surgery or radiation despite recommendations for active surveillance.

The push comes amid mounting evidence that careful monitoring is effective in managing low-grade cases. A U.K. study of 1,600 men found similar 15-year mortality rates between those who chose surgery, radiation or surveillance. Some doctors oppose the change, warning it could reduce patient compliance with follow-up care.
Space

Report of Newly-Discovered Asteroid Turns Out to Be... a Tesla Roadster (usatoday.com) 99

Founded in 1947, the Minor Planet Center is the official worldwide authority "for observing and reporting new asteroids, comets and other small bodies in the solar system," reports USA Today.

Unfortunately, "What an amateur astronomer recently took to be a newly discovered asteroid turned out to be a Tesla Roadster," The Minor Planet Center didn't initially consider the possibility when the organization announced the discovery on Jan. 2 of the unusual asteroid, complete with an official name: 2018 CN41. But less than 17 hours later, the Minor Planet Center issued an editorial notice that it would be deleting 2018 CN41 from its records... According to the Minor Planet Center's notice regarding the deletion, turns out the object was the Roadster, along with the Falcon Heavy rocket's upper stage.
Space

Hubble's Largest Panorama Ever Showcases 200 Million Stars (techspot.com) 7

NASA's Hubble Space Telescope has released the largest ever photomosaic featuring over 200 million stars -- all of which are bright than our own Sun. It consists of over 600 overlapping Hubble images and 2.5 billion pixels. "That is a huge number, yet only a fraction of the estimated one trillion stars in the Andromeda galaxy," reports TechSpot. "Many of Andromeda's less massive stars are beyond Hubble's sensitivity limit and thus, are not represented in the imaged."

"NASA has multiple sizes of the panoramic available for download, including the full-size 203 MB image (42,208 x 9,870) and a more user friendly 9 MB variant (10,552 x 2,468)."
Medicine

Ultra-Fast Cancer Treatments Could Replace Conventional Radiotherapy (bbc.com) 27

CERN's particle accelerator is being used in a pioneering cancer treatment called Flash radiotherapy. This method delivers ultra-high radiation doses in less than a second, minimizes side effects while targeting tumors more effectively than conventional radiotherapy. The BBC reports: In a series of vast underground caverns on the outskirts of Geneva, Switzerland, experiments are taking place which may one day lead to new generation of radiotherapy machines. The hope is that these devices could make it possible to cure complex brain tumors (PDF), eliminate cancers that have metastasized to distant organs, and generally limit the toll which cancer treatment exerts on the human body. The home of these experiments is the European Laboratory for Particle Physics (Cern), best known to the world as the particle physics hub that developed the Large Hadron Collider, a 27 kilometer (16.7 mile)-long ring of superconducting magnets capable of accelerating particles to near the speed of light.

Arguably Cern's crowning achievement was the 2012 discovery of the Higgs boson, the so-called "God Particle" which gives other particles their mass and in doing so lays the foundation for everything that exists in the universe. But in recent years, the centre's unique expertise in accelerating high-energy particles has found a new niche -- the world of cancer radiotherapy. Eleven years ago, Marie-Catherine Vozenin, a radiobiologist now working at Geneva University Hospitals (Hug), and others published a paper outlining a paradigm-shifting approach to traditional radiotherapy treatment which they called Flash. By delivering radiation at ultra-high dose rates, with exposures of less than a second, they showed that it was possible to destroy tumors in rodents while sparing healthy tissue. Its impact was immediate. International experts described it as a seminal breakthrough, and it galvanized fellow radiobiologists around the world to conduct their own experiments using the Flash approach to treat a wide variety of tumors in rodents, household pets, and now humans.

In recent years, animal studies have repeatedly shown that Flash makes it possible to markedly increase the amount of radiation delivered to the body while minimizing the impact that it has on surrounding healthy tissue. In one experiment, healthy lab mice which were given two rounds of radiation via Flash did not develop the typical side effects which would be expected during the second round. In another study, animals treated with Flash for head and neck cancers experienced fewer side effects, such as reduced saliva production or difficulty swallowing. Loo is cautiously optimistic that going forwards, such benefits may also translate to human patients. "Flash produces less normal tissue injury than conventional irradiation, without compromising anti-tumor efficacy -- which could be game-changing," he says. An additional hope is that this could then reduce the risk of secondary cancers (PDF), resulting from radiation-induced damage later in life, although it is still too early to know if that will be the case. [...] But the next phase of research is not only about testing whether Flash works in people. It's also about identifying which kind of radiation is the best one to use.

Science

Microplastics Block Blood Flow in the Brain, Mouse Study Reveals (nature.com) 26

Scientists have observed for the first time how microplastics move through and block blood vessels in mouse brains, according to research published in Science Advances this week. Using fluorescence imaging, researchers at Peking University tracked plastic particles as they were consumed by immune cells and accumulated in brain blood vessels, causing obstructions that persisted for up to four weeks and reduced blood flow. The study found that these blockages, which behaved similarly to blood clots, decreased the mice's mobility for several days.
Games

Complexity Physics Finds Crucial Tipping Points In Chess Games (arstechnica.com) 12

An anonymous reader quotes a report from Ars Technica: The game of chess has long been central to computer science and AI-related research, most notably in IBM's Deep Blue in the 1990s and, more recently, AlphaZero. But the game is about more than algorithms, according to Marc Barthelemy, a physicist at the Paris-Saclay University in France, with layers of depth arising from the psychological complexity conferred by player strategies. Now, Barthelmey has taken things one step further by publishing a new paper in the journal Physical Review E that treats chess as a complex system, producing a handy metric that can help predict the proverbial "tipping points" in chess matches. [...]

For his analysis, Barthelemy chose to represent chess as a decision tree in which each "branch" leads to a win, loss, or draw. Players face the challenge of finding the best move amid all this complexity, particularly midgame, in order to steer gameplay into favorable branches. That's where those crucial tipping points come into play. Such positions are inherently unstable, which is why even a small mistake can have a dramatic influence on a match's trajectory. Barthelemy has re-imagined a chess match as a network of forces in which pieces act as the network's nodes, and the ways they interact represent the edges, using an interaction graph to capture how different pieces attack and defend one another. The most important chess pieces are those that interact with many other pieces in a given match, which he calculated by measuring how frequently a node lies on the shortest path between all the node pairs in the network (its "betweenness centrality").

He also calculated so-called "fragility scores," which indicate how easy it is to remove those critical chess pieces from the board. And he was able to apply this analysis to more than 20,000 actual chess matches played by the world's top players over the last 200 years. Barthelemy found that his metric could indeed identify tipping points in specific matches. Furthermore, when he averaged his analysis over a large number of games, an unexpected universal pattern emerged. "We observe a surprising universality: the average fragility score is the same for all players and for all openings," Barthelemy writes. And in famous chess matches, "the maximum fragility often coincides with pivotal moments, characterized by brilliant moves that decisively shift the balance of the game." Specifically, fragility scores start to increase about eight moves before the critical tipping point position occurs and stay high for some 15 moves after that.
"These results suggest that positional fragility follows a common trajectory, with tension peaking in the middle game and dissipating toward the endgame," writes Barthelemy. "This analysis highlights the complex dynamics of chess, where the interaction between attack and defense shapes the game's overall structure."
Science

Pioneering CERN Scheme Will Pay Publishers More If They Hit Open-Science Targets (nature.com) 8

Leaders at CERN, Europe's particle-physics laboratory in Geneva, Switzerland, will introduce financial incentives for academic publishers to adopt open science policies as part of the organization's collective agreement with 11 particle-physics journals. From a report: The current scheme sees those journals publish work from the field openly and at no cost to authors, in exchange for bulk payments. Under the newly launched initiative, CERN will pay more to publishers that adopt polices such as use of public or open peer review and linking research to data sets, and less to those that do not. Some open-science specialists say the policy could be a game-changer in encouraging transparent science. Others caution that it could set a precedent for publishers to boost their fees in exchange for becoming more open. "Particle physics is large, international, highly complex, highly dynamic. Openness is the only really effective way of practising science in the discipline," says Kamran Naim, head of open science at CERN.

The move comes as a result of CERN's success in encouraging journals that publish its work to do so more openly, through a programme called the Sponsoring Consortium for Open Access Publishing in Particle Physics (SCOAP3). SCOAP3 launched in 2014 and its members include 3,000 libraries, research funders and research organizations worldwide, all of which contribute to a common fund at CERN. This is used to pay annual or quarterly lump sums to journals, in amounts depending on how many papers they publish. The initiative has so far supported the publication of more than 70,000 open-access articles. It has an annual budget of around $10.4 million.

Science

Game of Thrones Author Co-Writes Physics Paper on Superhero Virus 26

Los Alamos National Laboratory physicist Ian Tregillis and Game of Thrones author George R.R. Martin have published a physics paper deriving a mathematical model for the Wild Cards virus, a fictional pathogen that kills 90% of those infected while granting survivors either mutations ("Jokers") or superpowers ("Aces").

Published in the American Journal of Physics (February 2025), their paper develops a Lagrangian formulation to explain how the virus maintains its consistent "90:9:1" statistical distribution. The model accounts for both observable cases and hypothetical "crypto" carriers with undetectable effects.

The authors propose treating viral outcomes as a dynamical system, using concepts from ergodic theory and classical mechanics. The resulting model combines Lagrangian mechanics, functional analysis, and probability theory to distill the complex viral behavior into a single mathematical expression.
Science

People With ADHD Have Shorter Life Expectancy, Study Finds (cnn.com) 70

People with attention deficit hyperactivity disorder face significantly shorter life expectancy and higher mental health risks, a British study of over 30,000 patients found. The research, published in The British Journal of Psychiatry, showed men with ADHD lived 4.5 to 9 years less, while women's lives were shortened by 6.5 to 11 years.

The study compared primary care data from 30,029 adults with ADHD against 300,400 people without the condition. "Although many people with ADHD live long and healthy lives, our finding that on average they are living shorter lives than they should indicates unmet support needs," said Dr. Liz O'Nions, honorary research fellow at University College London. The study linked ADHD to increased risks of anxiety, depression, self-harm, and suicide, along with higher rates of smoking and alcohol use.
Space

Scientists Detect Chirping Cosmic Waves In an Unexpected Part of Space (apnews.com) 14

Scientists have detected cosmic "chorus waves" resembling bird chirps over 62,000 miles from Earth, a region where such waves have never been observed. "Scientists still aren't sure how the perturbations happen, but they think Earth's magnetic field may have something to do with it," reports the Associated Press. From the report: The chorus has been picked up on radio antennas for decades, including receivers at an Antarctica research station in the 1960s. And twin spacecraft -- NASA's Van Allen Probes -- heard the chirps from Earth's radiation belts at a closer distance than the newest detection. The latest notes were picked up by NASA's Magnetospheric Multiscale satellites, launched in 2015 to explore the Earth and sun's magnetic fields. The new research was published Wednesday in the journal Nature.

Chorus waves have also been spotted near other planets including Jupiter and Saturn. They can even produce high-energy electrons capable of scrambling satellite communications. "They are one of the strongest and most significant waves in space," said study author Chengming Liu from Beihang University in an email. The newfound chorus waves were detected in a region where Earth's magnetic field is stretched out, which scientists didn't expect. That raises fresh questions about how these chirping waves form. "It's very captivating, very compelling," Jaynes said. "We definitely need to find more of these events."

Medicine

Hospitals No Longer Allowed To Fix Machine That Costs Six Figures 136

An anonymous reader quotes a report from 404 Media: The manufacturer of a machine that costs six figures used during heart surgery has told hospitals that it will no longer allow hospitals' repair technicians to maintain or fix the devices and that all repairs must now be done by the manufacturer itself, according to a letter obtained by 404 Media. The change will require hospitals to enter into repair contracts with the manufacturer, which will ultimately drive up medical costs, a person familiar with the devices said.

The company, Terumo Cardiovascular, makes a device called the Advanced Perfusion System 1 Heart Lung Machine, which is used to reroute blood during open-heart surgeries and essentially keeps a patient alive during the surgery. Last month, the company sent hospitals a letter alerting them to the "discontinuation of certification classes," meaning it "will no longer offer certification classes for the repair and/or preventative maintenance of the System 1 and its components." This means it will no longer teach hospital repair techs how to maintain and fix the devices, and will no longer certify in-house hospital repair technicians. Instead, the company "will continue to provide direct servicing for the System 1 and its components." [...]

In a brochure for hospitals, Terumo advertises both its device and its maintenance program: "Advanced, precision medical equipment requires genuine parts and top-quality, specialized service -- just as getting the best medical care from qualified specialists. Terumo Cardiovascular Service has the unrivaled expertise, experience, equipment, and parts to provide the optimal level of planned service and repairs needed. Use Terumo Cardiovascular Service and avoid exposure to liability issues." A spokesperson for Terumo told 404 Media that the company "saw declining participation in this program and determined that the best way forward was to require servicing through Terumo Cardiovascular's genuine in-house Service team to continue to ensure Terumo devices are properly maintained."

"Terumo Cardiovascular's Biomed Certification Program was originally structured to train non-Terumo personnel (hospital Biomeds) to service Terumo heart-lung machines and associated hardware. Properly maintained medical devices are necessary for optimal performance which is essential for quality of patient care and outcomes," they added. "Hospitals' existing Terumo Cardiovascular Biomed certifications will remain valid through their expiration dates but will not be renewed once they expire."
"It's no secret that America's healthcare system is the most expensive, and this is one of the reasons why. These machines are actually highly reliable, we've had a low cost of service for it over the last few years. And when something isn't right, we have people in-house who can fix it," a source familiar with Terumo machine repair said. "But the cost of having a service contract with a manufacturer, you're probably talking 10 times the cost. It's not a big deal having a contract for one device, but when that starts happening across many devices, it adds up in the end. If you took every hospital in America and said for every medical device in the hospital, you need to put it on an OEM [original equipment manufacturer] maintenance contract, it would tank your financial system. You just can't do that."
Earth

Men Have Grown Twice As Much As Women Over Past Century, Study Shows 167

According to a new study published in the journal Biology Letters, men around the world have gained height and weight twice as fast as women over the past century. The Guardian reports: "We're seeing insights into how sexual selection has shaped the male and female body and how improved environments, in terms of food and a lower burden of disease, have freed us from our shackles," said Prof Lewis Halsey at the University of Roehampton. Halsey and his colleagues used data from the World Health Organization, overseas authorities and UK records to see how height and weight have changed with living conditions. The latter was measured by the human development index (HDI), a score based on life expectancy, time in education and per capita income, which ranges from zero to one.

Analysis of records from dozens of countries found that for every 0.2 point increase in HDI, women were on average 1.7cm taller and 2.7kg heavier, while men were 4cm taller and 6.5kg heavier. This suggests that as living conditions improve, both height and weight increase, but more than twice as fast in men than women. To see whether similar trends played out within countries, the researchers delved into historical height records in the UK where HDI rose from 0.8 in 1900 to 0.94 in 2022. During the first half of the century, average female height increased 1.9% from 159cm to 162cm, while average male height rose 4% from 170cm to 177cm. "To put this in perspective, about one in four women born in 1905 was taller than the average man born in 1905, but this dropped to about one in eight women for those born in 1958," Halsey said.

Writing in Biology Letters in a study titled "The sexy and formidable male body: men's height and weight are condition-dependent, sexually selected traits," the scientists speculate that women's sexual preferences may have fueled a trend for taller, more muscular men -- although in an age of obesity, heavy does not necessarily mean muscular. Stature and physique are prime indicators of health and vitality, Halsey said, while sexual selection also favors men who are better able to protect and defend their partners and offspring against others. "Women can find men's height attractive because, potentially, it makes them more formidable, but also because being taller suggests they are well-made," said Halsey. "As they've grown up, they haven't been affected by the slings and arrows of a bad environment, so they've reached more of their height potential. It's an indicator that they're well-made."
Mars

Edge of Mars' Great Dichotomy Eroded Back By Hundreds of Kilometers (arstechnica.com) 12

Ars Technica's John Timmer reports: In Monday's issue of Nature Geoscience, a team of UK-based researchers tackle a big one: Mars' dichotomy, the somewhat nebulous boundary between its relatively elevated southern half, and the low basin that occupies its northern hemisphere, a feature that some have proposed also served as an ancient shoreline. The new work suggests that the edge of the dichotomy was eroded back by hundreds of kilometers during the time when an ocean might have occupied Mars' northern hemisphere. [...] The new work focuses on an area called Mawrth Vallis, which sits at the edge of the dichotomy. Relative to the northern basin, it's a kilometer-high plateau cut by a major outflow channel that seems to have been caused by one or more massive floods. The slopes surrounding the plateau feature different types of clay-derived minerals, suggesting the area had been subject to interactions between the original materials and water.

Rather than focusing on the plateau itself, the work focuses on the neighboring lowlands, which include a large region dotted with thousands of buttes and mesas that rise roughly a kilometer above the surrounding plains. Using data from the ESA's Mars Express mission, they determine that these features tend to top out at the same height as the nearby plateau. And, using data from NASA's Mars Reconnaissance Orbiter, they determined that the clays present along the slopes match those found on the plateau as well. Their conclusion from this is that the mesas and buttes are the remains of what was once a far larger plateau, which was largely eroded away on the side facing the northern basin. And that erosion took place across a pretty significant distance, as the buttes extend hundreds of kilometers away from the present highlands. And, just as at the highland plateau, these mounds hint at a water-based process that modified the rocks from the top down. That's because the deeper clays are often magnesium-rich, which tends to happen when water comes in contact with volcanic rocks or material with similar chemistry. Closer to the surface, things transition to aluminum- and iron-rich clays. These clays can occur when the water source is acidic or can be simply due to longer exposure to water, as the magnesium clays are a bit more soluble.

The huge area covered by these mounds gives a sense of just how significant this erosion was. "The dichotomy boundary has receded several hundred kilometers," the researchers note. "Nearly all intervening material -- approximately 57,000 cubic kilometers over an area of 284,000 square kilometers west of Ares Vallis alone -- has been removed, leaving only remnant mounds." Based on the distribution of the different clays, the team argues that their water-driven formation took place before the erosion of the material. This would indicate that water-rock interactions were going on over a very wide region early in the history of Mars, which likely required an extensive hydrological cycle on the red planet. As the researchers note, a nearby ocean would have improved the chances of exposing this region to water, but the exposure could also have been due to processes like melting at the base of an ice cap. Complicating matters further, many of the mounds top out below one proposed shoreline of the northern ocean and above a second. It's possible that a receding ocean could have contributed to their erosion. But, at the same time, some of the features of a proposed shoreline now appear to have been caused by the general erosion of the original plateau, and may not be associated with an ocean at all.

Earth

Scientists Probe Mysterious Oxygen Source Possibly Discovered on the Sea Floor (cnn.com) 31

CNN has the latest on "a startling discovery made public in July that metallic rocks were apparently producing oxygen on the Pacific Ocean's seabed, where no light can penetrate.

"Initial research suggested potato-size nodules rich in metals, predominantly found 4,000 meters (13,100 feet) below the surface in the Clarion-Clipperton Zone, released an electrical charge, splitting seawater into oxygen and hydrogen through electrolysis." The unprecedented natural phenomenon challenges the idea that oxygen can only be made from sunlight via photosynthesis. Andrew Sweetman, a professor at the UK's Scottish Association for Marine Science who was behind the find, is embarking on a three-year project to investigate the production of "dark" oxygen further... Uncovering dark oxygen revealed just how little is known about the deep ocean, and the Clarion-Clipperton Zone, or CCZ, in particular. The region is being explored for the deep-sea mining of rare metals contained in the rock nodules. The latter are formed over millions of years, and the metals play a key role in new and green technologies...

Understanding the phenomenon better could also help space scientists find life beyond Earth, [Sweetman] added... Officials at NASA are interested in the research on dark oxygen production because it could inform scientific understanding of how life might be sustained on other planets without direct sunlight, Sweetman said. The space agency wants to run experiments to understand the amount of energy required to potentially produce oxygen at higher pressures that occur on Enceladus and Europa, the icy moons of Saturn and Jupiter, respectively, he added. Those moons are among the targets for investigating the possibility of life.

Deep-sea mining companies are aiming to mine the cobalt, nickel, copper, lithium and manganese contained in the nodules for use in solar panels, electric car batteries and other green technology. Some companies have taken issue with Sweetman's research. Critics say deep-sea mining could irrevocably damage the pristine underwater environment and that it could disrupt the way carbon is stored in the ocean, contributing to the climate crisis.

CNN's article also notes Massachusetts microbiologist Emil Ruff, who found unexpected oxygen far below the Canadian prairie in water isolated from the atmosphere for more than 40,000 years.

"Nature keeps surprising us," he said. "There are so many things that people have said, 'Oh, this is impossible,' and then later it turns out it's not."
Space

A 'Hubble Crisis'? New Measurement Confirms Universe is Expanding Too Fast for Current Models (phys.org) 88

"The universe is expanding faster than predicted by theoretical models," writes Phys.org, "and faster than can be explained by our current understanding of physics." There's now been new confirmation of this (published in The Astrophysical Journal Letters) by a team led by Dan Scolnic, an associate professor of physics at Duke University.

And this means the so-called Hubble tension "now turns into a crisis," said Dan Scolnic, who led the research team... This is saying, to some respect, that our model of cosmology might be broken." Measuring the universe requires a cosmic ladder, which is a succession of methods used to measure the distances to celestial objects, with each method, or "rung," relying on the previous for calibration. The ladder used by Scolnic was created by a separate team using data from the Dark Energy Spectroscopic Instrument (DESI), which is observing more than 100,000 galaxies every night from its vantage point at the Kitt Peak National Observatory. Scolnic recognized that this ladder could be anchored closer to Earth with a more precise distance to the Coma Cluster, one of the galaxy clusters nearest to us. "The DESI collaboration did the really hard part, their ladder was missing the first rung," said Scolnic. "I knew how to get it, and I knew that that would give us one of the most precise measurements of the Hubble constant we could get, so when their paper came out, I dropped absolutely everything and worked on this non-stop."

To get a precise distance to the Coma cluster, Scolnic and his collaborators used the light curves from 12 Type Ia supernovae within the cluster. Just like candles lighting a dark path, Type Ia supernovae have a predictable luminosity that correlates to their distance, making them reliable objects for distance calculations. The team arrived at a distance of about 320 million light-years, nearly in the center of the range of distances reported across 40 years of previous studies — a reassuring sign of its accuracy. "This measurement isn't biased by how we think the Hubble tension story will end," said Scolnic. "This cluster is in our backyard, it has been measured long before anyone knew how important it was going to be."

The results? "It matches the universe's expansion rate as other teams have recently measured it," writes Phys.org, "but not as our current understanding of physics predicts it. The longstanding question is: is the flaw in the measurements or in the models? Scolnic's team's new results add tremendous support to the emerging picture that the root of the Hubble tension lies in the models..."

And the article closes with this quote from Scolnic: "Ultimately, even though we're swapping out so many of the pieces, we all still get a very similar number. So, for me, this is as good of a confirmation as it's ever gotten. We're at a point where we're pressing really hard against the models we've been using for two and a half decades, and we're seeing that things aren't matching up," said Scolnic.

"This may be reshaping how we think about the universe, and it's exciting! There are still surprises left in cosmology, and who knows what discoveries will come next?"

Medicine

After PFAS Contamination on English Channel Island, Government Panel Recommends Bloodletting for Those Affected (theguardian.com) 71

Jersey is an island in the English channel, "a self-governing British Crown Dependency near the coast of northwest France," according to Wikipedia — population: 103,267.

But now some residents of Jersey "have been recommended bloodletting to reduce high concentrations of 'forever chemicals' in their blood," reports the Guardian, "after tests showed some islanders have levels that can lead to health problems." Private drinking water supplies in Jersey were polluted by the use of firefighting foams containing PFAS (per- and polyfluoroalkyl substances) at the island's airport, which were manufactured by the U.S. multinational 3M. .. Bloodletting draws blood from a vein in measured amounts. It is safe and the body replenishes the blood naturally, but it must be repeated until clean...

In response to the blood results, the government established an independent PFAS scientific advisory panel to advise public policy. The panel's first report recommended that the government should look at offering bloodletting to affected residents. "Studies show that bloodletting is an effective way to lower levels of PFAS in blood," said Ian Cousins, one of the panel members, though he added that there were no guarantees the process would prevent or cure diseases associated with the chemicals. The therapy costs about £100,000 upfront and then as much as £200,000 a year to treat 50 people. The panel is also considering the benefit of the drug cholestyramine, which a study has shown reduces PFAS in blood more quickly and cheaply, albeit with possible side effects. The government says it plans to launch a clinical service by early 2025.

Contamination persisted on the island for decades. "We know they started to use 3M's firefighting foam in the 1960s and then ramped up in the 1990s in weekly fire training exercises, after which foam started to appear in nearby streams," said Jeremy Snowdon, a former Jersey airport engineer who drank contaminated water for years. He has measured elevated levels of PFAS in his own blood and has high cholesterol.

The article includes this quote from one of the 88 residents of the polluted area found to have high levels of PFAS after blood testing. "I just want this out of my body. I don't want to end up with bladder cancer."
Medicine

America's Top Three Insurers Reaped $7.3 Billion From Their Drug-Middlemen's Markups, FTC Says (nbcnews.com) 87

America's Federal Trade Commission has been "raising antitrust concerns" about them for years, reports NBC News.

The latest? America's three largest drug middlemen "inflated the costs of numerous life-saving medications by billions of dollars over the past few years, the FTC said in a report Tuesday." The top pharmacy benefit managers (PBMs) — CVS Health's Caremark Rx, Cigna's Express Scripts and UnitedHealth Group's OptumRx — generated roughly $7.3 billion through price hikes over about five years starting in 2017, the FTC said. The "excess" price hikes affected generic drugs used to treat heart disease, HIV and cancer, among other conditions, with some increases more than 1,000% of the national average costs of acquiring the medications, the commission said. The FTC also said these so-called Big Three health care companies — which it estimates administer 80% of all prescriptions in the U.S. — are inflating drug prices "at an alarming rate, which means there is an urgent need for policymakers to address it...."

Some of the steepest drug markups were "hundreds and thousands of percent," according to Tuesday's report, which highlights just how profitable specialty drugs have become for the three leading PBMs. Cancer drugs alone made up nearly half of the $7.3 billion, the commission wrote, with multiple sclerosis medications accounting for another 25%. Dispensing highly marked-up specialty drugs was a massive income stream for the companies in 2021, the FTC found. Out of tens of thousands of drugs dispensed, the top 10 specialty generics alone made up nearly 11% of the companies' pharmacy-related operating income that year, the agency estimated. Across the 51 drugs the agency analyzed, the Big Three's price-markup revenue surged from $522 million in 2017 to $2.1 billion in 2021, the report said.

"The FTC found that 22 percent of specialty drugs dispensed by PBM-affiliated pharmacies were marked up by more than 1,000 percent," reports The Hill, "while 41 percent were marked up between 100 and 1,000 percent. Among those drugs marked up by more than 1,000 percent, half of them were marked up by more than 2,000 percent."

And the nonprofit site progressive news site Common Dreams shares some examples from the FTC's 60-page report: "For the pulmonary hypertension drug tadalafil (generic Adcirca), for example, pharmacies purchased the drug at an average of $27 in 2022, yet the Big Three PBMs marked up the drug by $2,079 and paid their affiliated pharmacies $2,106, on average, for a 30-day supply of the medication on commercial claims," the publication notes. That's a staggering average markup of 7,736%... The new analysis follows a July 2024 report that revealed Big Three PBM-affiliated pharmacies received 68% of the dispensing revenue generated by specialty drugs in 2023, a 14% increase from 2016...

Responding to the FTC report, Emma Freer, senior policy analyst for healthcare at the American Economic Liberties Project — a corporate accountability and antitrust advocacy group — said in a statement Tuesday that "the FTC's second interim report lays bare the blatant profiteering by PBM giants, which are marking up lifesaving drugs like cancer, HIV, and multiple sclerosis treatments by thousands of percent and forcing patients to pay the price."

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