Several tombs and a leaden sarcophagus likely dating from the 14th century have been uncovered by archaeologists at Notre Dame Cathedral in Paris as work continues on the building's reconstruction after its devastating 2019 fire. From a report: The burial sites "of remarkable scientific quality" were unearthed during preparatory work for rebuilding the ancient church's spire at the central spot where the transept crosses the nave, France's culture ministry announced late Monday. Among the tombs was a "completely preserved, human-shaped sarcophagus made of lead." It is thought the coffin was made for a senior dignitary in the 1300s -- the century after the cathedral's construction. As well as the tombs, elements of painted sculptures were found just beneath the current floor level of the cathedral, identified as parts of the original 13th-century rood screen -- an architectural element separating the altar area from the nave.

An anonymous reader quotes a report from Motherboard: Our universe is connected by a cosmic web made of giant threads of dark matter and gas that stretch across millions of light years and intersect at "nodes" populated by dense clusters of galaxies. This vast network shapes the distribution and evolution of galaxies in fundamental ways that scientists are trying to unravel with ever-sharper observations and advanced simulations. Now, a team led by Callum Donnan, a postgraduate student in astronomy at the University of Edinburgh, have identified a key correlation between the chemical makeup of galaxies and their location within the cosmic web. Using both real-life observations and computer simulations, the team found that "galaxies closer to nodes [display] higher chemical enrichment than those farther away," a discovery that reveals some of the mysterious dynamics that link the universe, according to a study published on Monday in Nature Astronomy.

To home in on this question, Donnan and his colleagues examined galaxies within about a billion light years of the Milky Way observed by the Sloan Digital Sky Survey in New Mexico, which covers a huge area of the sky. The team studied the elemental makeup of gasses in the interstellar spaces within these real-life galaxies, a property that is known as gas-phase metallicity. The results revealed that galaxies close to the nodes of the cosmic web were richer in "metals," which in astronomy refers to any element heavier than helium. A weaker correlation was also observed with proximity to the web's filaments, which are the threads that stretch across the universe and link nodes together. The team ran sophisticated cosmological simulations using the IllustrisTNG platform, which supported the observational findings. Significantly, the approach revealed that a galaxy's position in the cosmic web modulates its chemical content even when other factors, such as the density of a particular region in the universe, are taken into account.

Naturally, that raises the question of why galaxies located near nodes are enriched with more metals compared to those distributed along filaments or in empty "voids" within the cosmic web. Donnan's team isolated two major drivers of this relationship: The absorption of gas from outside of galaxies and the evolution of stars and dark matter inside of them. Galaxies feed on gasses that are strewn across space in the intergalactic medium, but those that are further from nodes consume much more of this outside material than those close to nodes. Since intergalactic gas is metal-poor, it dilutes the enriched gas of far-flung galaxies, lowering their overall gas-phase metallicities. Galaxies near nodes don't consume as much of this metal-poor material, which helps to keep them chemically enriched with higher concentrations of heavier elements. In addition, galaxies close to nodes seem to have matured earlier than those located at a distance. These galaxies had a head-start in birthing new stars and collecting dark matter, which is a mysterious substance that makes up most of the matter in the universe.

Two hours. That's about how much time elapsed between the discovery of asteroid 2022 EB5 and when it reached Earth's atmosphere. The asteroid is only the fifth one to have been detected before impact. CNET reports: Astronomer Krisztian Sarneczky first spotted the asteroid on March 11 with a telescope at the Piszkesteto observatory in Hungary. He reported the sighting to the International Astronomical Union's Minor Planet Center, which tracks near-Earth objects and comets. News of the asteroid spread from there, and calculations showed the space rock had a 100% chance of impact north of Iceland. Fortunately, the asteroid was very small, roughly 1 meter (3.3 feet) in diameter -- that's half the height of basketball superstar Michael Jordan. An asteroid that small will safely burn up in our planet's atmosphere, but the dainty size also makes it hard to spot.

The thought of an asteroid discovery mere hours before reaching us might make you think "yikes," but the European Space Agency described the news as "rather positive." Researchers have done an excellent job tracking bigger asteroids, so it's impressive they're now finding some of the smaller, sneakier ones. "All five asteroids, spotted before impact, were found since 2008, illustrating how much asteroid observation technologies have improved in the last years," ESA said in a statement. While 2022 EB5 was relatively tiny, infrasound detectors picked up on the likely impact, which ESA said suggested an energy release equivalent to a magnitude 4.0 earthquake. As detection systems get more sophisticated, it might be possible to warn communities when a small asteroid is inbound.

An anonymous reader shares a report: While US health experts closely monitor upticks of COVID-19 cases in Europe as well as the global rise of the omicron subvariant BA.2, Pfizer is renewing calls for fourth doses of COVID-19 vaccine. In an interview Sunday on CBS' Face the Nation, Pfizer CEO Albert Bourla said that a fourth dose -- aka a second booster -- is "necessary."

"The protection what we are getting from the third [doses], it is good enough -- actually, quite good for hospitalizations and deaths," Dr. Bourla said. But, "it's not that good against infections" with omicron, and "it doesn't last very long." He reported that Pfizer is "working very diligently" to come up with a new dose that will protect against all variants and provide longer-lasting protection.

The US astronaut Mark Vande Hei has made it through nearly a year in space, but now faces what could be his trickiest assignment: riding a Russian capsule back to Earth in the midst of deepening tension between the two countries. From a report: Nasa insists Vande Hei's homecoming at the end of the month remains unchanged, even as Russia's invasion of Ukraine has resulted in canceled launches, broken contracts and an escalating war of words from the leader of the Russian Space Agency. Many worry Dmitry Rogozin is putting decades of peaceful partnership at risk, most notably at the International Space Station (ISS). Vande Hei, who on Tuesday will break the US single spaceflight record of 340 days, is due to leave with two Russians aboard a Soyuz capsule for touchdown in Kazakhstan on 30 March. He will have logged 355 days in space. The world record of 438 days belongs to Russia.

The retired Nasa astronaut Scott Kelly, America's record-holder until Tuesday, is among those sparring with Rogozin, a longtime ally of Vladimir Putin. Kelly has returned a medal to the Russian embassy in Washington but believes the two sides "can hold it together" in space. "We need an example set that two countries that historically have not been on the most friendly of terms, can still work somewhere peacefully. And that somewhere is the International Space Station. That's why we need to fight to keep it," Kelly said. Nasa wants to keep the space station running until 2030, as do the European, Japanese and Canadian space agencies. The Russians have not committed beyond the original end date of 2024 or so.

An anonymous reader quotes a report from Time: Pfizer said it would no longer start new clinical trials in Russia and that it would donate all profits from its subsidiary in the country to Ukraine relief causes. At the same time, the drugmaker said in a statement that it will continue to supply medicines to Russia, out of fear that vulnerable patients such as children and elderly people who rely on its therapies could be harmed by any halt. The company "concluded that a voluntary pause in the flow of our medicines to Russia would be in direct violation of our foundational principle of putting patients first," according to the statement. Pfizer said it doesn't own or operate any manufacturing sites in Russia and plans to cease planned investments with local suppliers. Pfizer said it would work with the U.S. Food and Drug Administration and other regulators to move current clinical trials to alternative locations outside of Russia. Patients already enrolled in studies will continue to receive medications, the company said.

An anonymous reader quotes a report from Bloomberg: Sleeping in the dark may reduce your risk of heart disease and diabetes, a new study suggests. Exposure to overhead lighting during sleep at night, compared to sleeping in a dimly lit room, harms heart function during sleep and affects how well the body responds to insulin the next morning, researchers found. They suggest it is important for people to avoid or minimize the amount of light exposure during sleep, and that if people are able to see things well, it is probably too light. The study found that, when exposed to more light during sleep, the body went into a state of alert, with the heart rate rising and the body not being able to rest properly.

According to the scientists, people should not turn lights on, but if they do need to have some light -- for example, in the interests of safety for older adults -- it should be a dim light that is closer to the floor. The color is also important, with amber or a red/orange light less stimulating for the brain. White or blue light should be kept far away, the experts suggest. Blackout curtains or eye masks are a good option if outdoor light cannot be controlled. The study of 20 people found that insulin resistance occurred the morning after people slept in a light room. This is when cells in muscles, fat and the liver do not respond well to insulin and cannot use glucose from the blood for energy. To make up for it, the pancreas makes more insulin and, over time, blood sugar goes up. Senior study author Dr Phyllis Zee, chief of sleep medicine at Northwestern University Feinberg School of Medicine in America, said: "The results from this study demonstrate that just a single night of exposure to moderate room lighting during sleep can impair glucose and cardiovascular regulation, which are risk factors for heart disease, diabetes and metabolic syndrome." Dr Daniela Grimaldi, a co-first author and research assistant professor of neurology at Northwestern, added: "We showed your heart rate increases when you sleep in a moderately lit room. "Even though you are asleep, your autonomic nervous system is activated. That's bad. Usually, your heart rate together with other cardiovascular parameters are lower at night and higher during the day."

The study has been published in the Proceedings of the National Academy of Sciences.

sciencehabit writes: A debate over claims of room temperature superconductivity has now boiled over into the realm of scientific publishing. Administrators of arXiv, the widely used physics preprint server, recently removed or refused to post several papers from the opposing sides, saying their manuscripts include inflammatory content and unprofessional language. ArXiv has also banned one of the authors, Jorge Hirsch, a theoretical physicist at the University of California, San Diego (UCSD), from posting papers for 6 months.

The ban is "very unfair," Hirsch says. "I can't work if I can't publish papers." To some other scientists, arXiv's ban and removal of papers amount to stifling scientific debate. "The scientists that care about the issue and have the expertise to evaluate the arguments on both sides should be allowed to do so by accessing the preprints in question," Nigel Goldenfeld, a physicist at UCSD, wrote in an email to a wide range of physicists last week. "The alternative is that for cases such as this, we'll return to the pre-arXiv days when the science of the day is discussed in privately circulated preprints that are not accessible to the wider community." Daniel Arovas, another UCSD physicist, agreed: "Squelching what is essentially a purely scientific exchange -- even one where the respective parties engage in some distasteful accusations -- is highly problematic." But arXiv administrators argue the decision wasn't about science. "There are no papers in this whole chain that were rejected because we did not like the scientific content," says Ralph Wijers, a physicist at the University of Amsterdam who is the preprint server's board chair. "People's emotions became too affected. They got acrimonious."

High tea took on a whole new meaning for Andrew Hughes and his climbing crew. From a report: The group of adventurers held a tea party at 21,312 feet above sea level at Mount Everest's Camp 2 in Nepal last year, setting a new 'Guinness World Record -- which was officially recognized by Guinness this month -- for the highest tea party ever held. Hughes, a self-described high-endurance athlete from Seattle, Washington, said he first had the idea for the tea party early in the pandemic when Covid-19 travel restrictions and shutdowns meant expeditions were not possible. He said the isolation made him realize he missed the community more than the summits. "The greatest things in life are often those shared," Hughes said, adding he hopes the feat -- held on May 5, 2021 -- will "inspire others to seek their own dreams, no matter the heights." According to a news release, Hughes' "highest of high tea parties ... exceeded the previous mark by thousands of feet in altitude and was full of complexities, including carrying supplies through the treacherous Khumbu Icefalls."

Hong Kong is struggling to get a handle on its worst coronavirus outbreak since the start of the pandemic, warning that it doesn't have the testing capacity to carry out the strict strategy handed down by Beijing. From a report: In Shenzhen and Shanghai, in mainland China, officials imposed restrictions on millions of people within days of local outbreaks in order to test every single resident. But Hong Kong's chief executive, Carrie Lam, noted on Monday that her city doesn't have the same ability. "Hong Kong is very different from many mainland cities and therefore we cannot have any comparison," Mrs. Lam told reporters at a news conference. The difference amounts to resources and systems of governance, Mrs. Lam said. Shenzhen and Shanghai can test millions of people a day; Hong Kong's health officials can only test between 200,000 and 300,000 people a day.

Hong Kong, one of the last places in the world that is still trying to get rid of the virus instead of living with it, has reported more than 700,000 cases and 4,066 deaths since late January. It is a strategy that has been dictated by Beijing but one that appears increasingly out of reach for Hong Kong, which continues to hold freedoms that don't exist in the mainland. In the Chinese cities of Wuhan and Xian, officials halted daily life and confined residents to their homes for weeks until there were no more local cases. In Tianjin, they began testing every single resident after just 20 cases of coronavirus were reported. Further separating Hong Kong from the mainland's approach, Mrs. Lam said she would not consider tightening social-distancing measures because she had to take into how residents felt about them.

Pi day is here — 3/14. And to celebrate, NASA released their ninth annual NASA Pi Day Challenge — "some math problems related to current and future NASA missions."

MIT Bloggers released a videogame-themed video to welcome the class of 2026.

If you Google "pi day" (or Pi), you're given an interactive doodle that (when you click the pi symbol in the upper-left) presents a Simon-like game challenging you to type in approximations of pi to an ever-increasingnumber of digits.

Guinness World Records points out that the most accurate value of pi is 62,831,853,071,796 digits, "achieved by University of Applied Sciences (Switzerland) in Chur, Switzerland, on 19 August 2021." (Note: the number of digits looks suspiciously significant....)

And USA Today published an article which shares the history of how Pi Day got started. Former physicist Larry Shaw, who connected March 14 with 3.14, celebrated the first Pi Day at the Exploratorium with fruit pies and tea in 1988. The museum said Shaw led Pi Day parades there every year until his passing in 2017.

In 2009, the U.S. House of Representatives passed a resolution marking March 14 as National Pi Day.

The date is significant in the world of science. Albert Einstein was born on this day in 1879. The Exploratorium said it added a celebration of Einstein's life as part of its Pi Day activities after Shaw's daughter, Sara, realized the coincidence. March 14 also marks the death of renowned theoretical physicist Stephen Hawking, who passed away in 2018.
And "For those who don't enjoy math, you get pie," the article quips, noting that numerous pizza chains and restaurants are offering appropriately-adjusted one-day sale prices on pizza (and fruit) pies.

Instacart has even released a list showing which pie flavors enjoy the highest popularity over the national average in each of America's 50 states. ("New York — Boston Cream Pie. Washington — Marionberry Pie....")

This week Silicon Valley's Computer History Museum posted a PDF transcript (and video excerpts) from an interview with 81-year-old Margaret Hamilton, the programmer/systems designer who in the 1960s became director of the Software Engineering Division at the MIT Instrumentation Laboratory which developed the on-board flight software for NASA's Apollo program. Prior to that Hamilton had worked on software to detect an airplane's radar signature, but thought, "You know, 'I guess I should delay graduate school again because I'd like to work on this program that puts all these men on the Moon....'"

"There was always one thing that stood out in my mind, being in the onboard flight software, was that it was 'man rated,' meaning if it didn't work a person's life was at stake if not over. That was always uppermost in my mind and probably many others as well."

Interestingly, Hamilton had originally received two job offers from the Apollo Space Program, and had told them to flip a coin to settle it. ("The other job had to do with support systems. It was software, but it wasn't the onboard flight software.") But what's fascinating is the interview's glimpses at some of the earliest days of the programming profession: There was all these engineers, okay? Hardware engineers, aeronautical engineers and all this, a lot of them out of MIT... But the whole idea of software and programming...? Dick Battin, Dr. Battin, when they told him that they were going to be responsible for the software...he went home to his wife and said he was going to be in charge of software and he thought it was some soft clothing...
Hamilton also remembers in college taking a summer job as a student actuary at Travelers Insurance in the mid-1950s, and "all of a sudden one day word was going around Travelers that there were these new things out there called computers that were going to take away all of their jobs... Pretty soon they wouldn't have jobs. And so everybody was talking about it. They were scared they wouldn't have a way to make a living.

"But, of course, it ended up being more jobs were created with the computers than there were...."

Hamilton's story about Apollo 8 is amazing...

Right now an asteroid is zooming past earth "at a relatively close distance" reports Newsweek, "and the event can be viewed live." The asteroid, called 2022 ES3, will be traveling at 41,000 miles per hour when it comes between the moon and the Earth at around 2:18 p.m. ET on Sunday, March 13, according to NASA's Center for Near Earth Object Studies (CNEOS).

The space rock isn't expected to hit Earth. Instead, it will pass by at a distance of about 206,000 miles, which is about 87 percent of the distance between us and the moon.

The event provides a great viewing opportunity. An Italian astronomy organization called the Virtual Telescope Project, which often tracks asteroids and other space objects through the sky, is due to host a livestream of what it calls 2022 ES3's "very close, but safe, encounter with us" on its WebTV page starting at 18:30 UTC on March 13th.

Astronomers don't consider 2022 ES3 to be potentially hazardous, probably due to its size. The asteroid is predicted to be somewhere between 33 and 72 feet in diameter — about as wide as the length of a bowling lane.... [S]cientists track more than 28,000 near-Earth asteroids as they travel through the solar system. Around 900 of these are more than one kilometer, or 3,280 feet, in size.

"A long duration C2 solar flare launched an asymmetrical full halo coronal mass ejection into space," tweeted the nonprofit science site SpaceWeatherLive (sharing a black-and-white video). "The solar plasma cloud is likely to arrive at Earth late on Sunday, 13 March. Minor G1 geomagnetic storm conditions are likely with a chance of moderate G2 conditions."

Long-time Slashdot reader PuddleBoy shared this additional report from their web site: The solar flare lasted for hours and launched an asymmetrical full halo coronal mass ejection into space. Most of the ejecta is heading north-west but a significant part of the plasma cloud is expected to arrive at our planet. The coronal mass ejection was launched at a speed of about 600km/s which is a fairly average speed. This puts the likely arrival time at Earth late on Sunday, 13 March.

Minor G1 geomagnetic storm conditions (Kp5) are likely with a chance of moderate G2 conditions which equals a Kp-value of 6. Middle latitude locations might catch a glimpse of the aurora near the northern (or southern) horizon under optimal conditions.

"The European Space Agency has announced it has chosen a team to make oxygen on the moon," reports Digital Trends.

"The team, led by aerospace manufacturer Thales Alenia Space, will design and build a payload to create oxygen from lunar soil." [C]arrying oxygen into space using rockets is inefficient, so it would be better if astronauts could find ways to make what they need in the places they are exploring. This principle is called in-situ resource utilization and is a key idea for future missions to the moon and Mars.

The payload for the moon will be designed to create between 50 and 100 grams of oxygen from the dusty material which covers the moon, called regolith. The aim is to extract 70% of the available oxygen in the sample within a 10 day period. That time limit is because it will need to operate within the window of available solar power in a lunar day, which is around two weeks long.

Previous experiments and concepts have shown that it is possible to extract oxygen from lunar regolith, which is made up of around 40 — 45% oxygen by weight. Now, the challenge is to make a workable system within the constraints of size and materials.
A systems engineer from the space agency's design facility has high hopes for the project, according to a statement released Wednesday. "Being able to extract oxygen from moonrock, along with useable metals, will be a game-changer for lunar exploration, allowing the international explorers set to return to the Moon to 'live off the land' without being dependent on long and expensive terrestrial supply lines."

Last Exit: Space is a new documentary on Discovery+ exploring the possibility of humans colonizing planets beyond Earth, reports Ars Technica.. "Since it is produced and narrated by Werner Herzog and written and directed by his son Rudolph, however, it goes in a different direction than your average space documentary. It's weird, beautiful, skeptical, and even a bit funny...."

Other times, Werner opts for dryly funny narration of how bleak certain space colonization efforts may turn out. "The reality of life on Mars would be sobering," he says. "Astronauts would hunker down in radiation-proof bunkers, enjoying drinks of recycled urine...."

For most of the film, Rudolph focuses on two options for where humans might travel, land, and establish space colonies: Mars or an exoplanet in the Alpha Centauri system. Along the way, Last Exit: Space follows a pattern. First, it lists a problem that might make a certain space travel proposition impossible. Then it briefly explains the most promising solution to that problem as developed by modern science and engineering. Finally, it brings the interstellar dream crashing back down to Earth with a grim recounting of why the solution won't work.... "We know the next planet outside of our solar system is at least 5,000 years away," Werner tells Ars. "It's very hard to do that, and [whatever is there is] probably uninhabitable. And we know that on Mars, there's permanent radiation that will force us underground in little bunkers...."

As Last Exit: Space explores the logistics of a possible 5,000-year journey to Alpha Centauri, the film asks wild questions that touch matters of the human spirit, each with a diverse pool of optimistic and pessimistic answers. Is hibernation feasible? Could a non-hibernating skeleton crew function in a sane way? And how would the human act of copulation play out — both mechanically, in terms of being a reduced-gravity exercise, and genetically, in terms of possible in-breeding if a ship can't hold at least 40,000 colonists to keep the gene pool diverse...? [Werner Herzog adds] "But as you hear it from Lucian Walkowicz, an astronomer in the film, it's very clear that we take her position: We shouldn't behave like locusts who are grazing everything empty here, then move on to the next planet. There's something not right to shift, to move our population to other planets, and it's a part of all these ethical questions....

[Space colonization] will fail. It is inevitable. You cannot travel to the next [Alpha Centauri exoplanet] that is 200,000 years away. Period. Good luck...."

The filmmakers make it clear that they admire and appreciate efforts to understand space and our universal neighbors. But in describing "space colonization" as "a dirty word," Rudolph paraphrases Walkowicz's film-ending pitch: "There is already a cross-generational spaceship operating right now — and we're already on it. Earth is a luxuriously furnished, wonderfully self-rejuvenating place, so we'd better treat it well...."

Werner admits that he does have some interest in space travel. "I would love to go out on Mars on a mission... if I had a camera with me," he says.

Rudolph immediately interrupts: "Yes, but I want to stop my dad. Don't encourage him on this, please. I want him to stay on Earth."

Ever since Russia invaded Ukraine, the fate of the International Space Station, which has 15 partner nations and is the crown jewel of unity in space between NASA and Russia, has been up in the air (figuratively, of course). What we do know is that there are no plans to abandon NASA astronaut Mark Vande Hei on the space station, despite a number of stories claiming otherwise. "Vande Hei is scheduled to return to Earth in a Soyuz capsule at the end of this month, landing in Kazakhstan," reports Ars Technica. "NASA officials are expected to be there to greet him and bring him back to the United States." Ars Technica sets the record straight and explains where these Russian "threats" originated: The source of this "news" appears to be a video published more than a week ago by a Kremlin-aligned publication, RIA Novosti. Roscosmos TV provided footage for the video, but in sharing it acknowledged that the video was a "joke." Now, this is an exceptionally poor joke given the tensions on Earth, but it is important to understand that sharing a video a week ago does not mean Russia is threatening to leave Vande Hei behind. Nothing has changed since the video was posted. Since the beginning of this crisis, NASA officials have said operations with Russian colleagues working on the space station have proceeded nominally. "Operations have not changed at all," one NASA source confirmed Friday. On Monday, NASA's manager of the International Space Program, Joel Montalbano, is scheduled to speak at a news conference about upcoming spacewalks. He likely will say something similar.

Additionally, Vande Hei could not be abandoned. At present there are three other Americans living on board the International Space Station -- Raja Chari, Kayla Barron, and Thomas Marshburn. There is also an allied astronaut, Matthias Maurer, from Germany. NASA has its own transportation to and from the station, so Vande Hei can be assured of a safe ride home whenever NASA wants. The status of the ISS partnership is subject to change, of course. It could do so quite quickly. Russia is doing horrible things in Ukraine, and the Western world has responded with harsh sanctions. No one really knows whether Vladimir Putin will decide to end Russian participation in the International Space Station. Certainly, making it appear to a domestic audience that he was stranding a NASA astronaut in space might make him look "strong" to some Russian people. But there are simply no indications this will happen.

This winter's flu vaccine was a particularly bad match for the most common influenza strain in circulation, a new analysis from the Centers for Disease Control and Prevention found. Gizmodo reports: Thankfully, the flu season was much milder than usual for the second year in a row, as ongoing covid-19 precautions likely blunted the spread of flu as well. The estimates come from the CDC's long-running surveillance program of people with suspected flu-like symptoms who visit various outpatient sites throughout the country. Overall, the odds of catching a case of confirmed flu were only slightly lower for vaccinated people, the researchers found. Against all flu strains detected at these sites, the vaccine was deemed to be 14% effective, as well as 16% effective at preventing cases of flu from A(H3N2) viruses, the predominant strain this winter. Numbers this low are far below the 50% threshold for a vaccine to be considered relatively useful, and they're not even high enough to reach statistical significance.

In the words of the researchers, who published their results in the CDC's Morbidity and Mortality Weekly Report, the vaccine "did not reduce the risk for outpatient respiratory illness caused by influenza A(H3N2) viruses that have predominated so far this season." Flu vaccines, even in a good year, are far from perfect. The strains of influenza virus that infect humans are constantly evolving, meaning that scientists have to try to predict what these strains will look like during the next flu season so that they can match them to the strains included in the vaccine (the vaccine will usually include four strains at a time). This guessing game often results in a vaccine that's around 50% to 60% effective, but sometimes, as is the case this year, the mismatch can get worse. It doesn't help that this year's main flu is H3N2, a subtype of flu already known for being harder to predict than others.

Today, March 11, 2022, marks two years since covid-19 was declared a pandemic by the World Health Organization. We've had lockdowns, vaccines, and arguments about how to move forward and live with this virus. We've watched the pandemic through numbers and data and memorials to the many lives lost, officially now over six million. It is likely this figure is a vast undercount. A study published in The Lancet this week estimated that the true number may be three times higher, at 18.2 million. Technology Review: And, in a statement marking the two-year anniversary, WHO director-general Tedros Adhanom Ghebreyesus warned: "Although reported cases and deaths are declining globally, and several countries have lifted restrictions, the pandemic is far from over -- and it will not be over anywhere until it's over everywhere."

Researchers have categorised more than 80,000 plant species worldwide and found that most of them will "lose" in the face of humanity -- going extinct because people don't need them. From a report: This means that plant communities of the future will be hugely more homogenised than those of today, according to the paper published in the journal Plants, People, Planet. The findings, which paint a stark picture of the threat to biodiversity, cover less than 30% of all known plant species, and as such are a "wake-up call," say the researchers, highlighting the need for more work in this field. "We're actually beginning to quantify what's going to make it through the bottleneck of the Anthropocene, in terms of numbers," said John Kress, botany curator emeritus at the Smithsonian's National Museum of Natural History and lead author of the paper. "It's not the future, it's happening. The bottleneck is starting to happen right now. And I think that's part of the wake-up call that we are trying to give here. It's something we might be able to slow down a little bit, but it's happening."