Businesses

23andMe Plans New Genetic Test on Risk of Getting Diabetes (fortune.com) 61

In an update to its genetic test, 23andMe is trying to make it easier for people to combat type 2 diabetes. From a report: When customers now purchase the company's $199 Health & Ancestry Service test, they'll get their saliva screened for type 2 diabetes, among a variety of other health conditions, the company said in a statement on Sunday. The test won't say for sure whether a person has diabetes or will definitely get it, but the results will provide insight into whether someone is at risk of becoming diabetic. According to 23andMe, its test to determine diabetes risk comes from an analysis of data the company collected from more than 2.5 million customers who opted in to its research. Scientists evaluated the user data and created a system of scoring a person's likelihood of getting type 2 diabetes based on more than 1,000 genetic factors.
The Internet

CSS To Get Support For Trigonometry Functions (zdnet.com) 135

CSS, or the language that styles and arranges how page elements appear on a website, will soon get support for trigonometry functions such as sine, cosine, tangent, and others, ZDNet is reporting. From the report: The new trigonometry functions were approved at the end of February in a meeting of the World Wide Web Consortium (W3C) CSS Working Group. The new functions approved and set to join the CSS standard are: Sine - sin(), cosine - cos(), tangent - tan(), arccosine - acos(), arcsine - asin(), arctangent - atan(), arctangent (of two numbers x and y) - atan2(), square root - sqrt(), square root of the sum of squares of its arguments - hypot(), and power of - pow().
Moon

Has the Great 'Moonrush' Begun? (thespacereview.com) 143

This week The Space Review published an essay by retired aerospace engineer Gerald Black, who worked in the aerospace industry for over 40 years and tested various rocket engines, including the ascent stage engine of the Apollo lunar module.

"The Moonrush is now on," he argues "fueled by entrepreneurs dreaming of profits from Earth's nearest neighbor." Leading the Moonrush are a bunch of private companies developing small lunar landers and rovers to explore the Moon. On February 21, the first mission of the Moonrush embarked aboard a Falcon 9 rocket.

The Beresheet lunar lander built by Israel's SpaceIL was launched as a secondary payload, sharing the ride with the Indonesian communications satellite PSN-6. After reaching geostationary transfer orbit, Beresheet and the communications satellite separated from the Falcon 9 launcher. The communications satellite will propel itself to geostationary Earth orbit. Meanwhile, Beresheet is slowly raising its orbit. In early April the spacecraft will enter lunar orbit, then land on the Moon. Israel Aerospace Industries, the company that built the lander for SpaceIL, announced plans in January to partner with the German company OHB to offer a commercial lunar payload delivery service to the European Space Agency.

Black also notes that while Google never awarded its $20 million Lunar X grand prize, many teams are still active, including Astrobotic Technology, Moon Express, ispace inc., TeamIndus and PTScientists -- and that NASA will be awarding $2.6 billion in commercial moon exploration contracts over the next decade under its Commercial Lunar Payload Services program. The first mission under this program could be launched as soon as late this year... Blue Origin is developing a much larger lunar lander called Blue Moon that can land several metric tons of cargo on the Moon. And the German companies OHB and MT Aerospace have tapped Blue Origin's New Glenn rocket and Blue Moon lander to ferry a payload to the Moon in 2023.
Around-the-moon tourism could begin as soon as 2023, Black writes, while Bigelow Aerospace's CEO "is dreaming about establishing facilities on the lunar surface that could host tourists and others." And finally, landers and rovers will soon confirm whether there's accessible water hiding in the moon's perpetually dark craters -- and will hunt for other valuable resources. Rovers that include sample analysis laboratories like the one aboard the Curiosity rover on Mars will provide details about the constituents of the lunar rocks and soil. Deposits of gold, platinum group metals, and rare earth metals are likely to be found. Especially promising in this regard are the numerous impact craters on the Moon. High concentrations of precious metals have been found in craters where asteroids impacted the Earth.

Riches are there to be had, and mining may well become a major industry on the Moon.

Biotech

Genetically Engineered Seafood Coming To a Restaurant Near You (indianapublicmedia.org) 140

"The first genetically-modified animal for human consumption could be arriving in grocery stores across the United States as early as next year." Long-time Slashdot reader tomhath tipped us off to Indiana Public Media's report on AquaBounty Technologies: AquaBounty will produce a GMO salmon that CEO Ron Stotish says will grow faster than freshwater-raised fish. "It does so because we've given it the ability, using the same biological process that regulates growth in the unmodified salmon, to grow about twice as fast reaching market rate about half the time," Stotish says. The technology has been around since the 1990s, but it took until 2015 to receive approval from the U.S. Food and Drug Administration, due to concerns about people eating genetically-modified animals. The genetic makeup of the biotech fish takes a growth-hormone regulatory gene from the Pacific Chinook salmon with a promoter gene from an ocean pout and puts it into the genome of an Atlantic salmon. The result causes for the growth hormone to remain on leading to faster growth rate than non GMO salmon.

The modified fish is able to grow to market size using 25 percent less feed than the traditional salmon, increasing cost efficiency... Stotish says his operation causes less harm than traditional fish farming. "We're not using coastal waterways, we're not putting antibiotics and medications into the water," Stotish says. "Our fish are in a controlled environment, we don't need antibiotics, we don't have to treat for sea lice."

The company says that every year Americans consume about 350,000 tons of Atlantic salmon -- more than 95% of which has to be imported.
Medicine

A Doctor Remotely Told A Patient He Was Going To Die Using A Video-Link Robot (bbc.com) 223

dryriver quotes the BBC: A doctor in California told a patient he was going to die using a robot with a video-link screen. Ernest Quintana, 78, was at Kaiser Permanente Medical Center in Fremont when a doctor — appearing on the robot's screen — informed him that he would die within a few days. A family friend wrote on social media that it was "not the way to show value and compassion to a patient". The hospital says it "regrets falling short" of the family's expectations.

Mr Quintana died the next day.

Government

Ajit Pai's Rosy Broadband Deployment Claim May Be Based On Gigantic Error (arstechnica.com) 121

An anonymous reader quotes a report from Ars Technica: Pai's claim was questionable from the beginning, as we detailed last month. The Federal Communications Commission data cited by Chairman Pai merely showed that deployment continued at about the same rate seen during the Obama administration. Despite that, Pai claimed that new broadband deployed in 2017 was made possible by the FCC "removing barriers to infrastructure investment." But even the modest gains cited by Pai rely partly on the implausible claims of one ISP that apparently submitted false broadband coverage data to the FCC, advocacy group Free Press told the FCC in a filing this week.

The FCC data is based on Form 477 filings made by ISPs from around the country. A new Form 477 filer called Barrier Communications Corporation, doing business as BarrierFree, suddenly "claimed deployment of fiber-to-the-home and fixed wireless services (each at downstream/upstream speeds of 940mbps/880mbps) to census blocks containing nearly 62 million persons," Free Press Research Director Derek Turner wrote. "This claimed level of deployment stood out to us for numerous reasons, including the impossibility of a new entrant going from serving zero census blocks as of June 30, 2017, to serving nearly 1.5 million blocks containing nearly 20 percent of the U.S. population in just six months time," Turner wrote. "We further examined the underlying Form 477 data and discovered that BarrierFree appears to have simply submitted as its coverage area a list of every single census block in each of eight states in which it claimed service: CT, DC, MD, NJ, NY, PA, RI, and VA." In reality, BarrierFree's website doesn't market any fiber-to-the-home service, and it advertises wireless home Internet speeds of up to just 25mbps, Free Press noted.
BarrierFree appears to have ignored the FCC's instructions to report service only in census blocks in which an ISP currently offers service and instead simply "listed every single census block located in eight of the states in which it's registered as a CLEC [competitive local exchange carrier]."

As a result of BarrierFree's claimed level of deployment, it skewed the FCC's overall data significantly. "Pai claimed that the number of Americans lacking access to fixed broadband with speeds of at least 25Mbps down and 3Mbps up 'has dropped by over 25 percent, from 26.1 million Americans at the end of 2016 to 19.4 million at the end of 2017,'" reports Ars. "With BarrierFree's erroneous filing removed, 'the number of Americans lacking access to a fixed broadband connection at the 25Mbps/3Mbps threshold declined to 21.3 million, not 19.4 million,' Free Press wrote."
Space

NASA Captures Unprecedented Images of Supersonic Shockwaves (phys.org) 37

As NASA looks into developing planes that can fly faster than sound without creating "sonic booms," the space agency has captured unprecedented photos of the interaction of shockwaves from two supersonic aircraft. Phys.Org reports: When an aircraft crosses that threshold -- around 1,225 kilometers (760 miles) per hour at sea level -- it produces waves from the pressure it puts on the air around it, which merge to cause the ear-splitting sound. In an intricate maneuver by "rock star" pilots at NASA's Armstrong Flight Research Center in California, two supersonic T-38 jets flew just 30 feet (nine meters) apart below another plane waiting to photograph them with an advanced, high-speed camera, the agency said. The rendezvous -- at an altitude of around 30,000 feet -- yielded mesmerizing images of the shockwaves emanating from both planes. You can view all of the photos via NASA.
Space

SpaceX's Crew Dragon Capsule Returns To Earth After Historic Test Flight (nbcnews.com) 121

SpaceX's Crew Dragon capsule returned safely to Earth early Friday, wrapping up its inaugural mission to the International Space Station and signaling that the U.S. may soon be able to ferry astronauts to and from space without relying on Russian spacecraft. From a report: The uncrewed capsule splashed down in the Atlantic Ocean, off the east coast of Florida, at 8:45 a.m. ET after spending almost a week at the space station. The spacecraft undocked from the orbiting outpost Friday at 2:32 a.m. ET to begin its descent. "This is an amazing achievement in American history," NASA administrator Jim Bridenstine said from the space agency's Johnson Space Center in Houston. "These are all capabilities that are leading to a day where we are launching American astronauts on American rockets from American soil." The Crew Dragon capsule was lofted into orbit March 2 by a SpaceX Falcon 9 rocket from Cape Canaveral, Florida. The flight was a crucial test of the new spacecraft, a seven-passenger vehicle that SpaceX has been developing for the past five years.
Earth

Encouragement Without Education Backfires On Recycling Efforts (gizmodo.com) 220

Longtime Slashdot reader Alok writes: High contamination in recycled garbage, such as plastic bags mixed in with the recyclable plastic waste, are causing major problems for sustainability efforts in U.S. This has been exposed as a big problem recently, due to recent stricter China import rules on importing waste materials that led to changes in the sourcing pipelines. Cities such as Philadelphia have ended up processing nearly half of the recycling garbage using waste-to-energy incinerators instead, where they're being burned alongside garbage. "Today, the average U.S. recyclable load is about 25 percent contaminated," reports Gizmodo. "To make their commodities saleable, material recovery facilities started hiring more 'pickers' and buying more equipment to remove items that shouldn't be in the recycling, in addition to slowing down their processing lines." [C]ommunities like Philadelphia are going have to generate cleaner material that is more marketable," Scott McGrath, Environmental Planning Director at the City of Philadelphia Streets Department, said, adding that the city will be focusing more of its efforts on educating residents about what can and cannot be recycled. McGrath said if Philly can convince residents to stop tossing plastic bags in the recycling bin, that alone would be a big deal.

Anne Germain, Vice President of Technical and Regulatory Affairs at the National Waste and Recycling Association, an industry trade group, said public education was something the recycling industry as a whole had let slide over the years. "We were more about encouraging recycling than saying stop doing this or that," she said. This, combined with the widespread adoption of single stream, has made the public increasingly enthusiastic about throwing everything in their blue bins, resulting in a lot of what Center for American Progress representative Kristina Costa calls "aspirational recycling," or attempting to recycle garbage. "Once you start saying more and more materials are acceptable, it seems that a lot of people start to think everything is acceptable," Germain said, adding that the increased complexity of packaging today compared with a few decades ago has only added to the confusion.
Medicine

A Third Person May Have Been Cured of HIV (newscientist.com) 47

An anonymous reader quotes a report from New Scientist: Following news of a man in the UK who has been free of HIV since his cancer treatment, a similar case has been reported by researchers who treated a patient in Germany. Together, they add to evidence that it may be possible to cure HIV. The virus infects cells of the immune system, which are made in the bone marrow. A man known as the "Berlin patient" was the first person to become HIV-free after cancer treatment, back in 2007. To treat his leukemia -- a cancer of the immune system -- he was given a treatment that involved killing nearly all his immune cells with radiotherapy or drugs, and then replacing them with cells from a donor. This donor was naturally resistant to HIV, thanks to a rare but natural mutation in a gene called CCR5.

A possible third case was then announced today, at the Conference on Retroviruses and Opportunistic Infections in Seattle. Biopsies from the gut and lymph nodes of this "Dusseldorf patient" show no infectious HIV after three months off antiviral drugs -- only old fragments of viral genes that wouldn't be able to multiply, says Annemarie Wensing of University Medical Center Utrecht in the Netherlands, who worked on this case. This is just like the Berlin and London patients, she says. Researchers are tracking the few other people who have HIV and have then had a bone marrow transplant from someone with the CCR5 mutation in a collaboration called IciStem. As well as the three reported so far, there are two others who haven't yet stopped taking antiviral medications, says Javier Martinez-Picado of the IrsiCaixa AIDS Research Institute in Barcelona.

Medicine

Amazon's Joint Health-Care Venture Finally Has a Name: Haven (cnbc.com) 46

"Haven" is the new name of the joint health-care venture between Amazon, JPMorgan, and Berkshire Hathaway. The CEOs of the three companies last January announced they were teaming up to tackle rising health-care costs. They formed a nonprofit company and named renowned surgeon, author and speaker Dr. Atul Gawande as CEO in June. CNBC reports: Prior to the big reveal, many industry insiders referred to the venture as "ABC" or "ABJ." The company said the name choice of "Haven" lines up with its mission to be a "partner" to care providers and to focus on the health-care needs of the 1.2 million Amazon, Berkshire Hathaway and J.P Morgan workers. Since his appointment, Gawande has been meeting with employees at these three companies to understand their health-care experiences. In addition to its new brand, the company also unveiled a website with more details about the venture, including a number of areas of focus. These include: Improving the process of navigating the complex health-care system, and accessing affordable treatments and prescription drugs.

Haven also said on its website that it's interested in working with clinicians and insurance companies to improve the overall health-care system, suggesting the venture wants to work with existing players such as insurers, providers and pharmacy benefit managers rather than uprooting them. The website also includes a letter where Gawande describes Haven's role as being "an advocate for the patient and an ally to anyone -- clinicians, industry leaders, innovators, policymakers, and others -- who makes patient care and costs better."

Science

Decade-Long Study: Measles Vaccine Doesn't Cause Autism, Even in High-Risk Kids (reuters.com) 358

The measles, mumps and rubella (MMR) vaccine isn't associated with an increased risk of autism even among kids who are at high risk because they have a sibling with the disorder, a Danish study suggests. From a report: Concerns about a potential link between the MMR vaccine and autism have persisted for two decades, since a controversial and ultimately retracted 1998 paper claimed there was a direct connection. Even though subsequent studies haven't tied inoculation to autism, fear about the risk has weighed on parents so much in several communities across Europe and the U.S. that vaccination rates have been too low to prevent a spate of measles outbreaks.

In the current study, researchers examined data on 657,461 children. During this time, 6,517 kids were diagnosed with autism. Kids who got the MMR vaccine were seven percent less likely to develop autism than children who didn't get vaccinated, researchers report in the Annals of Internal Medicine. "Parents should not skip the vaccine out of fear for autism," said lead study author Dr. Anders Hviid of the Statens Serum Institut in Copenhagen, Denmark. "The dangers of not vaccinating includes a resurgence in measles which we are seeing signs of today in the form of outbreaks," Hviid said by email.

Space

Deflecting an Asteroid Will Be Harder Than Scientists Thought (upi.com) 180

schwit1 shares a report from UPI: According to new asteroid collision models designed by scientists at Johns Hopkins University, deflecting a large rock headed for Earth will be harder than previously thought. Using the most up-to-date findings on rock fracturing, researchers developed computer models to more accurately simulate asteroid collisions. For the newest study, scientists decided to divide the model into two phases. Phase one modeled the immediate fracturing that happens in the wake of a collision -- the processes that play in a matter of seconds. The second phase simulated the gravitational re-accumulation process that happens over the course of several hours or days.

The first phase of the updated model showed a large asteroid is not destroyed by a much smaller asteroid. Instead, millions of cracks form throughout, the core fractures and a crater is left behind. During phase two, the fractured core exerts a strong gravitational pull on the smaller pieces of debris and shrapnel broken during the impact. Because the asteroid did not crack completely during phase one, the space rock retained significant strength. If scientists are going to develop an asteroid deflection strategy that can actually work, they need to know how much force it really takes to destroy or deflect one. The latest study -- published in the newest issue of the journal Icarus -- showed it's more force than was originally thought.

Science

Sleep Helps To Repair Damaged DNA In Neurons, Scientists Find (theguardian.com) 98

An anonymous reader quotes a report from The Guardian: Scientists have discovered that broken DNA builds up in brain cells in the daytime and repair work reverses the damage only during sleep. For an act so universal, sleep has enormous benefits. Found in organisms from flies to worms and jellyfish, it restores the body and helps learning and memory. But despite extensive research, the purpose of sleep is still mysterious. Lior Appelbaum from Bar-Ilan University and his student, David Zada, reasoned that if sleep had evolved in all organisms with a nervous system, then it might be working at the level of individual neurons.

To find out, they genetically engineered small, transparent zebrafish so the chromosomes in their neurons carried colorful chemical tags. The researchers then used a powerful, specialized microscope to watch how the chromosomes moved in the neurons, and how often DNA was broken, when the fish were awake and asleep. When the fish were awake, the chromosomes did not move much and broken strands of DNA built up in the neurons, as part of the normal wear and tear of life. If the fish were sleep-deprived, by tapping on their tank for example, some of the neurons accumulated so much genetic damage they were in danger of dying off. But, when the fish fell asleep, the picture changed. The scientists noticed that the chromosomes changed shape far more often in sleeping fish, and that DNA damage in their neurons plummeted. The same happened when the researchers added a sleep-inducing drug to the tank, causing the fish to fall asleep in the daytime.
"Appelbaum said that chromosomes are constantly changing shape to allow the cells' natural repair mechanisms to mend DNA damage at different points," the report adds. "When awake, the repair work cannot keep up with the rate at which damage builds up, but in the calm hours of sleep, the repair mechanisms have a chance to get on top of the job." The study has been published in Nature Communications.
Medicine

What It's Like To Smoke Salvia For Science (vice.com) 72

Slashdot reader and Motherboard writer dmoberhaus was the final participant in the world's first brain imaging study on salvinorin A, the psychoactive chemical in salvia divinorum. He wrote about what it's like to participate in a psychedelic drug trial, and why he volunteered to smoke the world's least favorite hallucinogen for science. Here's an excerpt from his report: I was first introduced to salvia when I was a freshman in high school, and by the time I graduated I had smoked it about a dozen times. In retrospect, I would not describe a single one of those experiences as "pleasant," "enjoyable," or "fun." The last time I used salvia was almost a decade ago, and during that trip I became convinced that I had been irreversibly transformed into a suspension bridge. Good times. Despite a history of bad experiences with the substance, I volunteered for the Johns Hopkins salvinorin A study out of a suspicion that salvia probably had more to offer than what I experienced in high school. As a teen, each of my salvia experiences was under less than ideal conditions -- usually at a party or in a park after curfew. These sorts of situations lend themselves to paranoia and anxiety, which don't mix well with a strong dissociative hallucinogen. I figured if the settings were changed to a relaxed environment where I was surrounded by medical professionals, perhaps the nature of the trip would as well.
[...]
For the first salvia session I laid on the couch and donned an eye mask while [Manoj Doss, a postdoctoral researcher who specializes in memory] sat at the far end of the room with the smoking apparatus. The simple device consisted of a small glass bulb with a plastic hose connected to the top and was described to me as an "FDA-approved crack pipe." Along the bottom of the bulb was a barely noticeable residue of a white crystalline substance, which I was informed was one dose of 99.9% pure salvinorin A. I was given one end of the hose and instructed to begin a 45-second long inhale as Doss vaporized the salvinorin A with a butane torch. At the same time, Clifton began to play a new age soundtrack through speakers and came to put his hand on my leg to ground me during the trip. When the 45 seconds were up, I exhaled and felt the effects of the salvia almost immediately.

The first thing I noticed was the feeling of my body dissolving. Shortly after I began feeling the physical effects, the hallucinations began. I felt as though my head had split in two and a patterned stream began flowing from both sides of my face. This stream was a "harlequin pattern" of large brown and white diamonds that flowed away from me and began to form the "boundary" of an infinite three-dimensional space. These diamonds continued to tessellate to an infinite point and I felt as though I were suspended above this expanse, hanging like a figure head hangs off the bow of a ship. Throughout the trip, I remember being overcome by the profound beauty of the scene I was witnessing. If I tried to focus, I could remember that in base reality I was in a room in Johns Hopkins, but that didn't alleviate the feeling of being in an entirely separate reality, as though I were sitting in a container that cordoned me off from the 'normal' world.
In summary, Oberhaus said "the experience was quite pleasant." He added: "I only had a brief moment of panic when it seemed like one of the notes in the new age soundtrack had been held for far too long. I began to worry that time was dilating and that I might be trapped in this space for eternity. When the music progressed to the next note, however, the panic quickly subsided and time resumed its normal cadence."

Oberhaus then took a higher dose the following day in an MRI machine. While the first dose of salvia in the machine didn't produce anything special, likely because it was a placebo, a very low dose, or that he had made some error during inhalation, the second dose in the machine resulted in a slightly less intense trip than the very first dose. "The reason, I think, was that the loud and persistent sounds of the MRI machine kept me tethered to the outside world and I was unable to fully immerse myself in the world that the salvia was generating," writes Oberhaus. "Still, I would describe it as a pleasant and visually striking experience."
Medicine

Scientists Report a Second Person Has Been Cured of HIV (reuters.com) 139

Scientists have reported that an HIV-positive man in Britain has been cleared of the AIDS virus after he received a bone marrow transplant from an HIV resistant donor. This is the second known adult worldwide to be cleared of HIV; the first was an American man, Timothy Brown, who became known as the Berlin patient when he underwent similar treatment in Germany more than a decade ago. According to HIV experts, Brown is still HIV-free. Reuters reports: Almost three years after receiving bone marrow stem cells from a donor with a rare genetic mutation that resists HIV infection - and more than 18 months after coming off antiretroviral drugs - highly sensitive tests still show no trace of the man's previous HIV infection. The case is a proof of the concept that scientists will one day be able to end AIDS, the doctors said, but does not mean a cure for HIV has been found. The man is being called "the London patient," in part because his case is similar to the first known case of a functional cure of HIV.

"There is no virus there that we can measure. We can't detect anything," said Ravindra Gupta, a professor and HIV biologist who co-led a team of doctors treating the man. Gupta described his patient as "functionally cured" and "in remission," but cautioned: "It's too early to say he's cured." Gupta, now at Cambridge University, treated the London patient when he was working at University College London. The man had contracted HIV in 2003, Gupta said, and in 2012 was also diagnosed with a type of blood cancer called Hodgkin's Lymphoma. In 2016, when he was very sick with cancer, doctors decided to seek a transplant match for him. "This was really his last chance of survival," Gupta told Reuters in an interview. The donor -- who was unrelated -- had a genetic mutation known as "CCR5 delta 32," which confers resistance to HIV. The transplant went relatively smoothly, Gupta said, but there were some side effects, including the patient suffering a period of "graft-versus-host" disease - a condition in which donor immune cells attack the recipient's immune cells.

Science

Welding Glass To Metal Is Now Possible Using An Ultrafast Laser System, Researchers Report (phys.org) 99

An anonymous reader quotes a report from Phys.Org: Scientists from Heriot-Watt University have welded glass and metal together using an ultrafast laser system, in a breakthrough for the manufacturing industry. Various optical materials such as quartz, borosilicate glass and even sapphire were all successfully welded to metals like aluminum, titanium and stainless steel using the Heriot-Watt laser system, which provides very short, picosecond pulses of infrared light in tracks along the materials to fuse them together. The new process could transform the manufacturing sector and have direct applications in the aerospace, defense, optical technology and even healthcare fields. Professor Duncan Hand, director of the five-university EPSRC Center for Innovative Manufacturing in Laser-based Production Processes based at Heriot-Watt, said: "Traditionally it has been very difficult to weld together dissimilar materials like glass and metal due to their different thermal properties -- the high temperatures and highly different thermal expansions involved cause the glass to shatter. Being able to weld glass and metals together will be a huge step forward in manufacturing and design flexibility."

He added: "The parts to be welded are placed in close contact, and the laser is focused through the optical material to provide a very small and highly intense spot at the interface between the two materials -- we achieved megawatt peak power over an area just a few microns across. This creates a microplasma, like a tiny ball of lightning, inside the material, surrounded by a highly-confined melt region. We tested the welds at -50C to 90C and the welds remained intact, so we know they are robust enough to cope with extreme conditions."
Mars

Probe From NASA's InSight Lander Burrows Into the Soil of Mars (space.com) 83

"The 'mole' aboard NASA's InSight Mars lander has encountered stiff resistance on its first subsurface sojourn beneath the surface of the Red Planet," reports Space.com: In a major mission milestone, InSight's Heat Flow and Physical Properties Package (HP3) instrument burrowed underground for the first time on Feb. 28. After 400 hammer blows over the course of four hours, the instrument apparently got between 7 inches and 19.7 inches (18 to 50 centimeters) beneath the red dirt -- but obstacles slowed its progress, mission team members said...

The $850 million InSight lander -- whose name is short for Interior Exploration using Seismic Investigations, Geodesy and Heat Transport -- touched down on Nov. 26. The spacecraft aims to map the Red Planet's interior in unprecedented detail. It will do this primarily by characterizing "marsquakes" and other vibrations with a suite of supersensitive seismometers, which was built by a consortium led by the French space agency CNES; and measuring subsurface heat flow with HP3, which DLR provided.

"I'm digging Mars!" announced NASA's official Twitter feed for the InSight robotic lander, adding "My self-hammering mole has started burrowing in, and my team is poring over the data..."
Science

Missing Out On Deep Sleep Causes Alzheimer's Plaques to Build Up (discovermagazine.com) 103

"Deep, non-REM sleep helps people's brains to wash away toxic proteins and waste, a new study found, reinforcing the link between sleep deprivation, aging and Alzheimer's disease," reports U.S. News & World Report.

Or, as Discover magazine puts it, "Getting enough deep sleep might be the key to preventing dementia." The discovery reinforces how critical quality sleep is for brain health and suggests sleep therapies might curb the advance of memory-robbing ailments, like Alzheimer's disease... Cerebrospinal fluid (CSF) churns through a system of brain tunnels piped in the spaces between brain cells and blood vessels. Scientists call it the glymphatic system. This system circulates nutrients like glucose, the brain's primary energy source, and washes away potentially toxic waste. And it may be the reason why animals even need sleep. The system takes out the brain's trash when we're asleep, and it shuts down when we're awake.

Maiken Nedergaard, a neurologist at the University of Rochester Medical Center in New York, who led the new research, and her team were curious if the system works best and clears more waste -- like Alzheimer's causing beta amyloid plaque -- when animals are in deep sleep. To find out, the researchers used six different anesthetics to put mice into deep sleep. Then they tracked cerebrospinal fluid as it flowed into the brain. As the mice slept, the researchers watched the rodents' brain activity on an electroencephalograph, or EEG, and recorded the animals' blood pressures and heart and respiratory rates. Mice anesthetized with a combination of two drugs, ketamine and xylazine, showed the strongest deep sleep brain waves and these brain waves predicted CSF flow into the brain, the researchers found.

The lead researcher now argues that focusing on sleep in the early stages of dementia "might be able to slow progression of the disease."
Science

Does Listening to Music Have a Negative Impact on Creativity? (slashgear.com) 79

We've all heard the studies. AmiMoJo quotes the health and science editor of Slashgear: A new study has found that listening to music may have a negative impact on creativity. This is contrary to the popular idea that music and creativity often go hand in hand. According to the researchers, the negative impact was found even in cases where the music had a positive impact on mood and was liked by the person listening to it. However, background noise didn't have the same effect...

Unlike music, the noise in a library provided a "steady state" environment, which had less of a disruptive effect on participants. Though studying with background music may not completely obliterate someone's ability to think creatively, the research indicates that you may do your best work without it.

But what do Slashdot's readers think? Do you listen to music when you're working -- or do you prefer the steady sounds of silence? Share your own experiences in the comments.

Does listening to music have a negative impact on creativity?

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