Earth

A Massive Impact Crater Has Been Detected Beneath Greenland's Ice Sheet (gizmodo.com) 172

An anonymous reader quotes a report from Gizmodo: An unusually large asteroid crater measuring 19 miles wide has been discovered under a continental ice sheet in Greenland. Roughly the size of Paris, it's now among the 25 biggest asteroid craters on Earth. An iron-rich asteroid measuring nearly a kilometer wide (0.6 miles) struck Greenland's ice-covered surface at some point between 3 million and 12,000 years ago, according to a new study published today in Science Advances. The impact would've flung horrific amounts of water vapor and debris into the atmosphere, while sending torrents of meltwater into the North Atlantic -- events that likely triggered global cooling (a phenomenon sometimes referred to as a nuclear or volcanic winter). Over time, however, the gaping hole was obscured by a 1,000-meter-tall (3,200-foot) layer of ice, where it remained hidden for thousands of years. Remarkably, the crater was discovered quite by chance -- and it's now the first large crater to be discovered beneath a continental ice sheet.
Earth

Climate Change is Making Hurricanes Even More Destructive, Research Finds (theguardian.com) 212

Hurricane Harvey swamped Houston with seven days of pounding rain last August. When scientists went back to look at historical weather patterns, they reported Harvey dumped 20 percent more rain than it typically would have. The culprit: climate change. From a report: High-resolution climate simulations of 15 tropical cyclones in the Atlantic, Pacific and Indian Oceans found that warming in the ocean and atmosphere increased rainfall by between 5% and 10%, although wind speeds remained largely unchanged. This situation is set to worsen under future anticipated warming, however. Researchers found that if little is done to constrain greenhouse gas emissions and the world warms by 3C to 4C this century then hurricane rainfall could increase by a third, while wind speeds would be boosted by as much as 25 knots.

"Climate change has exacerbated rainfall and is set to enhance the wind speed," said Christina Patricola, who undertook the study with her Lawrence Berkeley National Laboratory colleague Michael Wehner. "My hope is that this information can be used to improve our resilience to the kinds of extreme weather events we are going to have in the future." The research, published in the journal Nature, used climate models to see how factors such as air and ocean temperatures have influenced hurricanes. Projections into the future were then made, based upon various levels of planetary warming. The findings suggest that enormously destructive storms have already been bolstered by climate change and similar events in the future are on course to be cataclysmic.

Science

United Nations Considers a Test Ban on Evolution-Warping Gene Drives (technologyreview.com) 150

Bill Gates wants to end malaria, and so he's particularly "energized" about gene drives, a technology that could wipe out the mosquitoes that spread the disease. Gates calls the new approach a "breakthrough," but some environmental groups say gene drives are too dangerous to ever use. From a report: Now the sides are headed for a showdown. In a letter circulated this week, scientists funded by the Bill & Melinda Gates Foundation and others are raising the alarm over what they say is an attempt to use a United Nations biodiversity meeting this week in Sharm El-Sheikh, Egypt, to introduce a global ban on field tests of the technology. At issue is a draft resolution by diplomats updating the UN Convention on Biological Diversity, which -- if adopted -- would call on governments to "refrain from" any release of organisms containing engineered gene drives, even as part of experiments. The proposal for a global gene-drive moratorium has been pushed by environmental groups that are also opposed to genetically modified soybeans and corn. They have likened the gene-drive technique to the atom bomb.

In response, the Gates Foundation, based in Seattle, has been funding a counter-campaign, hiring public relations agencies to preempt restrictive legislation and to distribute today's letter. Many of its signatories are directly funded by the foundation. "This is a lobbying game on both sides, to put it bluntly," says Todd Kuiken, who studies gene-drive policy at North Carolina State University. (He says he was asked to sign the Gates letter but declined because he is a technical advisor to the UN.) New technology The gene-drive technique involves modifying a mosquito's DNA so that, when the insect breeds, it spreads a specific genetic change -- one that's bad for its survival.

Earth

Scientists Acknowledge Key Errors in Study of How Fast the Oceans Are Warming (washingtonpost.com) 280

A major study claimed the oceans were warming much faster than previously thought. But researchers now say they can't necessarily make that claim. From a report: Two weeks after the high-profile study was published in the journal Nature, its authors have submitted corrections to the publication. The Scripps Institution of Oceanography, home to several of the researchers involved, also noted the problems in the scientists' work and corrected a news release on its website, which previously had asserted that the study detailed how the Earth's oceans "have absorbed 60 percent more heat than previously thought."

"Unfortunately, we made mistakes here," said Ralph Keeling, a climate scientist at Scripps, who was a co-author of the study. "I think the main lesson is that you work as fast as you can to fix mistakes when you find them." The central problem, according to Keeling, came in how the researchers dealt with the uncertainty in their measurements. As a result, the findings suffer from too much doubt to definitively support the paper's conclusion about how much heat the oceans have absorbed over time.

The central conclusion of the study -- that oceans are retaining ever more energy as more heat is being trapped within Earth's climate system each year -- is in line with other studies that have drawn similar conclusions. And it hasn't changed much despite the errors. But Keeling said the authors' miscalculations mean there is a much larger margin of error in the findings, which means researchers can weigh in with less certainty than they thought.

Google

Google Accused of 'Trust Demolition' Over Health App (bbc.com) 60

A privacy expert is criticizing Google for taking over a controversial health app developed by AI firm DeepMind. The app in question -- Streams -- was first used to send alerts in a London hospital but hit headlines for gathering data on 1.6 million patients without informing them. DeepMind now wants the app to become an AI assistant for nurses and doctors around the world. BBC reports: One expert described the move as "trust demolition." Lawyer and privacy expert Julia Powles, who has closely followed the development of Streams, responded on Twitter: "DeepMind repeatedly, unconditionally promised to 'never connect people's intimate, identifiable health data to Google.' Now it's announced... exactly that. This isn't transparency, it's trust demolition," she added.
Space

Large, Strangely Dim Galaxy Found Lurking On Far Side of Milky Way (sciencemag.org) 68

A reader shares a report from Science Magazine: Circling our galaxy is a stealthy giant. Astronomers have discovered a dwarf galaxy, called Antlia 2, that is one-third the size of the Milky Way itself. As big as the Large Magellanic Cloud, the galaxy's largest companion, Antlia 2 eluded detection until now because it is 10,000 times fainter. Such a strange beast challenges models of galaxy formation and dark matter, the unseen stuff that helps pull galaxies together. The galaxy was discovered with data from the European Space Agency's Gaia satellite, a space telescope measuring the motions and properties of more than 1 billion stars in and around the Milky Way. Gabriel Torrealba, an astronomy postdoc at the Academia Sinica in Taipei, decided to sift the data for RR Lyrae stars. These old stars, often found in dwarf galaxies, shine with a throbbing blue light that pulses at a rate signaling their inherent brightness, allowing researchers to pin down their distance.

Gaia data helped the team see past the foreground stars. Objects in the Milky Way's disk are close enough for Gaia to measure their parallax: a shift in their apparent position as Earth moves around the sun. More distant stars appear fixed in one spot. After removing the parallax-bearing stars, the researchers homed in on more than 100 red giant stars moving together in the constellation Antlia, they report in a paper posted to the preprint server arXiv this week. The giants mark out a sprawling companion galaxy 100 times less massive than anything of similar size, with far fewer stars.

Medicine

Tantalizing But Preliminary Evidence of a 'Brain Microbiome' (sciencemag.org) 65

An anonymous reader quotes a report from Science Magazine: We know the menagerie of microbes in the gut has powerful effects on our health. Could some of these same bacteria be making a home in our brains? A poster presented here this week at the annual meeting of the Society for Neuroscience drew attention with high-resolution microscope images of bacteria apparently penetrating and inhabiting the cells of healthy human brains. The work is preliminary, and its authors are careful to note that their tissue samples, collected from cadavers, could have been contaminated. But to many passersby in the exhibit hall, the possibility that bacteria could directly influence processes in the brain -- including, perhaps, the course of neurological disease -- was exhilarating.

Talking hoarsely above the din of the exhibit hall on Tuesday evening, neuroanatomist Rosalinda Roberts of The University of Alabama in Birmingham (UAB), told attendees about a tentative finding that, if true, suggests an unexpectedly intimate relationship between microbes and the brain. Her lab looks for differences between healthy people and those with schizophrenia by examining slices of brain tissue preserved in the hours after death. About 5 years ago, neuroscientist Courtney Walker, then an undergraduate in Roberts's lab, became fascinated by unidentified rod-shaped objects that showed up in finely detailed images of these slices, captured with an electron microscope. Roberts had seen the shapes before. "But I just dismissed them, because I was looking for something else," she says. "I would say 'Oh, here are those things again.'" But Walker was persistent, and Roberts started to consult colleagues at UAB. This year, a bacteriologist gave her unexpected news: They were bacteria. Her team has now found bacteria somewhere in every brain they've checked -- 34 in all -- about half of them healthy, and half from people with schizophrenia.

Google

Google Is Absorbing DeepMind's Health Care Unit To Create An 'AI Assistant For Nurses and Doctors' 27

Google has announced that it's absorbing DeepMind Health, a part of its London-based AI lab DeepMind. "In a blog post, DeepMind's founders said it was a 'major milestone' for the company that would help turn its Streams app -- which it developed to help the UK's National Health Service (NHS) -- into 'an AI-powered assistant for nurses and doctors' that combines 'the best algorithms with intuitive design,'" reports The Verge. "Currently, the Streams app is being piloted in the UK as a way to help health care practitioners manage patients." From the report: DeepMind says its Streams team will remain in London and that it's committed to carrying out ongoing work with the NHS. These include a number of ambitious research projects, such as using AI to spot eye disease in routine scans. The news is potentially controversial given the upset in the UK caused by one of DeepMind's early deals with the NHS. The country's data watchdogs ruled in 2017 that a partnership DeepMind struck with the NHS was illegal, as individuals hadn't been properly informed about how their medical data would be used.

Another consistent worry for privacy advocates in the UK has been the prospect of Google getting its hands on this sort of information. It's not clear what the absorption of the Streams team into Google means in that context, but we've reached out to DeepMind for clarification. According to a report from CNBC, the independent review board DeepMind set up to oversee its health work will likely be shut down as a result of the move. More broadly speaking, the news clearly signals Google's ambitions in health care and its desire to get the most of its acquisition of the London AI lab. There have reportedly been long-standing tensions between DeepMind and Google, with the latter wanting to commercialize the former's work. Compared to Google, DeepMind has positioned itself as a cerebral home for long-sighted research, attracting some of the world's best AI talent in the process.
Movies

Douglas Rain, Voice of HAL 9000 In '2001: A Space Odyssey,' Dies At 90 (hollywoodreporter.com) 53

schwit1 shares a report from The Hollywood Reporter: Douglas Rain, the veteran Canadian stage actor who provided the soft and gentle voice of the rogue HAL 9000 computer for Stanley Kubrick's classic 2001: A Space Odyssey and its sequel, has died. He was 90. The first drafts of the 2001 script had HAL being voiced by a woman and was called Athena; afterward, it was decided that the computer should sound more like a man. Nigel Davenport, Martin Balsam and others were tried out -- and ruled out -- before and during filming of the 1968 sci-fi thriller.

"Well, we had some difficulty deciding exactly what HAL should sound like, and Marty just sounded a little bit too colloquially American, whereas Rain had the kind of bland mid-Atlantic accent we felt was right for the part,' Kubrick told Newsday film critic Joseph Gelmis in an interview for the 1970 book The Film Director as Superstar. Kubrick told Rain that he had made the computer "too emotional and too human." So, in late 1967, the actor flew to New York City and spent a day and a half -- about 9 1/2 hours in all -- to voice HAL. As reported on the blog 2010: The Year We Make Contact, Rain "did the recordings with his bare feet resting on a pillow, in order to maintain the required relaxed tone."

Science

Study Opens Route To Ultra-Low-Power Microchips (mit.edu) 41

Freshly Exhumed writes: A new approach to controlling magnetism in a microchip could open the doors to memory, computing, and sensing devices that consume drastically less power than existing versions. The approach could also overcome some of the inherent physical limitations that have been slowing progress in this area until now.

Researchers at MIT and at Brookhaven National Laboratory have demonstrated that they can control the magnetic properties of a thin-film material simply by applying a small voltage. Changes in magnetic orientation made in this way remain in their new state without the need for any ongoing power, unlike today's standard memory chips, the team has found. The new finding is being reported today in the journal Nature Materials, in a paper by Geoffrey Beach, a professor of materials science and engineering and co-director of the MIT Materials Research Laboratory; graduate student Aik Jun Tan; and eight others at MIT and Brookhaven.

As silicon microchips draw closer to fundamental physical limits that could cap their ability to continue increasing their capabilities while decreasing their power consumption, researchers have been exploring a variety of new technologies that might get around these limits. One of the promising alternatives is an approach called spintronics, which makes use of a property of electrons called spin, instead of their electrical charge. Because spintronic devices can retain their magnetic properties without the need for constant power, which silicon memory chips require, they need far less power to operate. They also generate far less heat -- another major limiting factor for today's devices.

Science

Better 'Nowcasting' Can Reveal What Weather is About To Hit Within 500 Meters (technologyreview.com) 45

Weather forecasting is impressively accurate given how changeable and chaotic Earth's climate can be. It's not unusual to get 10-day forecasts with a reasonable level of accuracy. But there is still much to be done. One challenge for meteorologists is to improve their "nowcasting," the ability to forecast weather in the next six hours or so at a spatial resolution of a square kilometer or less. From a report: In areas where the weather can change rapidly, that is difficult. And there is much at stake. Agricultural activity is increasingly dependent on nowcasting, and the safety of many sporting events depends on it too. Then there is the risk that sudden rainfall could lead to flash flooding, a growing problem in many areas because of climate change and urbanization. That has implications for infrastructure, such as sewage management, and for safety, since this kind of flooding can kill. So meteorologists would dearly love to have a better way to make their nowcasts. Enter Blandine Bianchi from EPFL in Lausanne, Switzerland, and a few colleagues, who have developed a method for combining meteorological data from several sources to produce nowcasts with improved accuracy.

Their work has the potential to change the utility of this kind of forecasting for everyone from farmers and gardeners to emergency services and sewage engineers. Current forecasting is limited by the data and the scale on which it is gathered and processed. For example, satellite data has a spatial resolution of 50 to 100 km and allows the tracking and forecasting of large cloud cells over a time scale of six to nine hours. By contrast, radar data is updated every five minutes, with a spatial resolution of about a kilometer, and leads to predictions on the time scale of one to three hours. Another source of data is the microwave links used by telecommunications companies, which are degraded by rainfall.

Space

Rocket Lab's Modest Launch Is Giant Leap For Small Rocket Business (nytimes.com) 36

Reader Iwastheone shares a report: A small rocket from a little-known company lifted off Sunday from the east coast of New Zealand, carrying a clutch of tiny satellites. That modest event -- the first commercial launch by a U.S.-New Zealand company known as Rocket Lab -- could mark the beginning of a new era in the space business, where countless small rockets pop off from spaceports around the world. This miniaturization of rockets and spacecraft places outer space within reach of a broader swath of the economy.

The rocket, called the Electron, is a mere sliver compared to the giant rockets that Elon Musk, of SpaceX, and Jeffrey P. Bezos, of Blue Origin, envisage using to send people into the solar system. It is just 56 feet tall and can carry only 500 pounds into space. But Rocket Lab is aiming for markets closer to home. "We're FedEx," said Peter Beck, the New Zealand-born founder and chief executive of Rocket Lab. "We're a little man that delivers a parcel to your door." Behind Rocket Lab, a host of start-up companies are also jockeying to provide transportation to space for a growing number of small satellites. The payloads include constellations of telecommunications satellites that would provide the world with ubiquitous internet access.

The payload of this mission, which Rocket Lab whimsically named "It's Business Time," offered a glimpse of this future: two ship-tracking satellites for Spire Global; a small climate- and environment-monitoring satellite for GeoOptics; a small probe built by high school students in Irvine, Calif., and a demonstration version of a drag sail that would pull defunct satellites out of orbit.

Math

How Nature Defies Math in Keeping Ecosystems Stable (quantamagazine.org) 103

Paradoxically, the abundance of tight interactions among living species usually leads to disasters in ecological models. New analyses hint at how nature seemingly defies the math. Veronique Greenwood, writing for Quantamagazine: Behind the beautiful facade of a rainforest, a savanna or a placid lake is a world teeming with contests and partnerships. Species are competing for space, consuming one another for resources, taking advantage of one another's talents, and brokering trades of nutrients. But there's something funny about this picture. When ecologists try to model ecosystems using math, they tend to find that the more interactions there are among species, the more unstable the system. For a simple ecosystem model to be stable, all the interactions among its species must be in perfect harmony. Maintaining that balancing act gets much harder, however, as the number of coupled species and the strengths of their interactions rise: Any disturbance or imbalance for one couple ripples outward and sows chaos throughout the network.

Bring in mutualisms, relationships in which species contribute directly to each other's survival, and things can really fly off the handle. Pairs of organisms that live off each other sometimes do so well in the mathematical simulations -- thriving exponentially in extreme cases, in what Robert May, the theoretical ecology pioneer, once called "an orgy of mutual benefaction" -- that everything else can go extinct. It seems unlikely that real ecosystems are quite this flimsy. In a new paper in Nature Communications, a pair of theoretical ecologists at the University of Illinois explored more precisely how the give-and-take in mutualism affects ecosystem stability and how, under the right conditions, it might contribute to it. Their result joins previous work in suggesting how real-world communities manage to be more resilient than the models imply.

Space

Did We Miss an Interstellar Comet Four Years Ago? (arxiv.org) 59

Long-time Slashdot reader RockDoctor writes: A paper published on Arxiv last week reports on a project to redetermine the "orbits of long period comets... We recently attempted to check, whether the assumption of a parabolic orbit for hundreds of comets discovered after 1950 is fully justified in all cases." The full work by Królikowska & Dybczynski remains in preparation (which is perfectly normal), but this intriguing result deserved early attention.

During this research we found an interesting case of the comet C/2014 W10 PANSTARRS.

(that's the 10th reported comet in fortnight W of year 2014, source : the PANSTARRS team)

After discovery on 2014-11-25, fourteen observations were made over three days, giving a first-estimate orbit with an eccentricity of 0.6039453. So far, so boring — as the temporary designation suggests, these get found on most days. But that orbit is subject to uncertainty so some more measurements were made on 2014-12-22 from a different observatory. When all of the data is considered, it becomes impossible to clearly assign an orbit to this object (this is possible if, for example, there is a fragmentation of the object between observations), but many of the solutions which can be obtained have a hyperbolic orbit — that is, the object is extra-solar.

If correct, this "post-covery" would double the size of the catalogue of interstellar objects known.

Unfortunately, the quality of the original data remains poor — estimates of the orbital eccentricity vary between 1.22 and 1.65 — which is in contrast to the prompt recognition and intense observation campaign for 'Oumuamua. The report's main conclusion is that

Our main purpose is to show that similar cases should be treated in future with greater care by more reliable preliminary orbit determination and alerting observers about the importance of the object to initiate more follow-up observations.

Which is exactly what happened with 'Oumuamua.

AI

AI Researchers Predict Alzheimer's Years Before Diagnosis (sciencedaily.com) 43

Slashdot reader pgmrdlm quotes Science Daily: Timely diagnosis of Alzheimer's disease is extremely important, as treatments and interventions are more effective early in the course of the disease. However, early diagnosis has proven to be challenging. Research has linked the disease process to changes in metabolism, as shown by glucose uptake in certain regions of the brain, but these changes can be difficult to recognize... Researchers trained [a] deep learning algorithm on a special imaging technology known as 18-F-fluorodeoxyglucose positron emission tomography (FDG-PET). In an FDG-PET scan, FDG, a radioactive glucose compound, is injected into the blood. PET scans can then measure the uptake of FDG in brain cells, an indicator of metabolic activity.

The researchers had access to data from the Alzheimer's Disease Neuroimaging Initiative (ADNI), a major multi-site study focused on clinical trials to improve prevention and treatment of this disease. The ADNI dataset included more than 2,100 FDG-PET brain images from 1,002 patients. Researchers trained the deep learning algorithm on 90 percent of the dataset and then tested it on the remaining 10 percent of the dataset. Through deep learning, the algorithm was able to teach itself metabolic patterns that corresponded to Alzheimer's disease. Finally, the researchers tested the algorithm on an independent set of 40 imaging exams from 40 patients that it had never studied. The algorithm achieved 100 percent sensitivity at detecting the disease an average of more than six years prior to the final diagnosis.

"We were very pleased with the algorithm's performance," Dr. Sohn said. "It was able to predict every single case that advanced to Alzheimer's disease

Science

How Biologists Are Creating Life-like Cells From Scratch (nature.com) 42

Built from the bottom up, synthetic cells and other creations are starting to come together and could soon test the boundaries of life. From a report: Researchers have been trying to create artificial cells for more than 20 years -- piecing together biomolecules in just the right context to approximate different aspects of life. Although there are many such aspects, they generally fall into three categories: compartmentalization, or the separation of biomolecules in space; metabolism, the biochemistry that sustains life; and informational control, the storage and management of cellular instructions.

The pace of work has been accelerating, thanks in part to recent advances in microfluidic technologies, which allow scientists to coordinate the movements of minuscule cellular components. Research groups have already determined ways of sculpting cell-like blobs into desired shapes; of creating rudimentary versions of cellular metabolism; and of transplanting hand-crafted genomes into living cells. But bringing all these elements together remains a challenge.

[...] Research groups have made big strides recreating several aspects of cell-like life, especially in mimicking the membranes that surround cells and compartmentalize internal components. That's because organizing molecules is key to getting them to work together at the right time and place. Although you can open up a billion bacteria and pour the contents into a test tube, for example, the biological processes would not continue for long. Some components need to be kept apart, and others brought together. "To me, it's about the sociology of molecules," says Cees Dekker, a biophysicist also at Delft University of Technology. For the most part, this means organizing biomolecules on or within lipid membranes. Schwille and her team are expert membrane-wranglers.

Starting about a decade ago, the team started adding Min proteins, which direct a bacterial cell's division machinery, to sheets of artificial membrane made of lipids. The Mins, the researchers found, would pop on and off the membranes and make them wave and swirl1. But when they added the Mins to 3D spheres of lipids, the structures burst like soap bubbles, says Schwille. Her group and others have overcome this problem using microfluidic techniques to construct cell-sized membrane containers, or liposomes, that can tolerate multiple insertions of proteins -- either into the membranes themselves or into the interior.

Science

How Dad's Stresses Get Passed Along To Offspring (scientificamerican.com) 109

An anonymous reader quotes a report from Scientific American: A stressed-out and traumatized father can leave scars in his children. New research suggests this happens because sperm "learn" paternal experiences via a mysterious mode of intercellular communication in which small blebs break off one cell and fuse with another. Carrying proteins, lipids and nucleic acids, these particles ejected from a cell act like a postal system that extends to all parts of the body, releasing little packages known as extracellular vesicles. Their contents seem carefully chosen. "The cargo inside the vesicle determines not just where it came from but where it's going and what it's doing when it gets there," says Tracy Bale, a neurobiologist at the University of Maryland School of Medicine. To probe the inheritance of such changes at the cellular level, Bale and co-workers performed a series of mouse experiments.

In one set of experiments [Jennifer Chan, a former PhD student that was part of the study] stressed a group of male mice, let them mate and looked at stress responses in the pups. The clincher was a set of in vitro fertilization -- like experiments in which she collected sperm from a male mouse that had never experienced induced stress. Half his sperm went into a lab dish with vesicles previously exposed to stress hormones. The other half was cultured with vesicles that had no contact with stress hormones. Chan injected sperm cells from each batch into eggs from a non-stressed female, then implanted the fertilized eggs -- zygotes -- into the same foster mom. The pups from non-stressed zygotes developed normally. Pups from stress-exposed zygotes, however, showed the same abnormal stress response as those whose dads had experienced stress before mating. That showed extracellular vesicles act as the conduit for transmitting paternal stress signals to the offspring, Chan says.

Robotics

A Robot Scientist Will Dream Up New Materials To Advance Computing (technologyreview.com) 41

An anonymous reader quotes a report from MIT Technology Review: In a laboratory that overlooks a busy shopping street in Cambridge, Massachusetts, a robot is attempting to create new materials. A robot arm dips a pipette into a dish and transfers a tiny amount of bright liquid into one of many receptacles sitting in front of another machine. When all the samples are ready, the second machine tests their optical properties, and the results are fed to a computer that controls the arm. Software analyzes the results of these experiments, formulates a few hypotheses, and then starts the process over again. Humans are barely required.

The setup, developed by a startup called Kebotix, hints at how machine learning and robotic automation may be poised to revolutionize materials science in coming years. The company believes it may find new compounds that could, among other things, absorb pollution, combat drug-resistant fungal infections, and serve as more efficient optoelectronic components. The company's software learns from 3-D models of molecules with known properties. Kebotix uses several machine-learning methods to design novel chemical compounds. The company feeds molecular models of compounds with desirable properties into a type of neural network that learns a statistical representation of those properties. This algorithm can then come up with new examples that fit the same model.
To strain out potentially useless materials, Kebotix uses another neural network and "then the company's robotic system tests the remaining chemical structures," reports MIT Technology Review. "The results of those experiments can be fed back into the machine-learning pipeline, helping it get closer to the desired chemical properties. The company dubs the overall system a 'self-driving lab.'"
NASA

NASA is Showering One City With Sonic Booms and Hoping No One Notices (cnet.com) 95

Eric Mack, reporting for CNET: NASA has been deliberately creating sonic booms off the coast of Galveston, Texas, since Monday in the hope that residents on the barrier island community won't be too bothered by the sound of an F/A-18 aircraft briefly going supersonic. That's because the research jet is performing a dive maneuver designed to reduce the normally thunderous sonic boom to what NASA calls a "quiet thump," more like the sound of a car door slamming. The test flights are aimed at measuring the community response to the new, quieter booms and are part of NASA's larger effort to develop a new, more muted supersonic plane that might be able to fly over land. Current regulations prohibit flights over land that generate sonic booms.
Science

Corneas Could Be the First Mainstream Application of Bioprinting (ieee.org) 35

A startup says it can replace donated eyes with 3D-printed corneas. From a report: Here's a futuristic problem that may not have occurred to you: If self-driving cars really catch on and the number of traffic fatalities plunges, so will the number of organs available for transplant. Currently, about 20 percent of donated organs come from people who die in car accidents. Luckily, there's a futuristic solution: 3D-printed organs.

This technology is far from ready for the clinic, as researchers are still trying to figure out how to print out complex tissue structures with blood vessels and nerves. But for one early indicator of progress in this field, look to the eye. Precise Bio, a North Carolina-based startup founded by several professors at the renowned Wake Forest Institute for Regenerative Medicine, is working on bioprinting tissues for a variety of medical applications. The company just announced that its first products will be for the eye -- starting with a human cornea suitable for transplantation. "We plan to put our printers in eye banks," says Precise Bio CEO Aryeh Batt.

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