"The planet Uranus emits more heat than it gets from the Sun," reports Science Daily , citing a new study led by University of Houston researchers, in collaboration with planetary scientists worldwide. "This means it's still slowly losing leftover heat from its early history," says the first author on the paper, "a key piece of the puzzle that helps us understand its origins and how it has changed over time."

The study found the planet emitting about 12.5% more heat than it absorbs via sunlight, which "suggests Uranus does have its own internal heat — an advance that not only informs NASA's future missions but also deepens scientists' understanding of planetary systems, including processes that influence Earth's climate and atmospheric evolution." The discovery resolves a long-standing scientific mystery about the giant planet, because observational analyses from Voyager 2 in 1986 didn't suggest the presence of significant internal heat — contradicting scientists' understanding of how giant planets form and evolve...

Additionally, the team's methodology provides testable theories and models that could also be applied to explore radiant energy of other planets within and beyond our solar system... It could even impact technology innovation and climate understanding on Earth [giving insights into "the fundamental processes that shape planetary atmospheres, weather systems and climate systems," said one of the paper's authors.]
The article adds that the researchers now think the planet "may have a different interior structure or evolutionary history compared to the other giant planets."

An anonymous reader quotes a report from the BBC: Drug treatment can help people newly diagnosed with ADHD (attention deficit hyperactivity disorder) to reduce their risk of substance misuse, suicidal behavior, transport accidents and criminality, a study suggests. These issues are linked to common ADHD symptoms such as acting impulsively and becoming easily distracted. Some 5% of children and 2.5% of adults worldwide are thought to be affected by the disorder -- and growing numbers are being diagnosed. The findings, published in the British Medical Journal (BMJ), confirm the wider potential benefits of drug treatment and could help patients decide whether to start medication, the researchers say. The researchers found taking ADHD medication was linked to reductions of first-time instances of:
- suicidal behavior - 17%
- substance misuse - 15%
- transport accidents - 12%
- criminal behavior - 13%

When recurrent events were analyzed, the researchers found ADHD medication was linked to reductions of:
- 15% for suicide attempts
- 25% for substance misuses
- 4% for accidental injuries
- 16% for transport accidents
- 25% for criminal behavior

alternative_right shares a report from Phys.org: Take note of the name: ReHMGB1. A new study pinpoints this protein as being able to spread the wear and tear that comes with time as it quietly travels through the bloodstream. This adds significantly to our understanding of aging. The researchers were able to identify ReHMGB1 as a critical messenger passing on the senescence signal by analyzing different types of human cells grown in the lab and conducting a variety of tests on mice. When ReHMGB1 transmission was blocked in mice with muscle injuries, muscle regeneration happened more quickly, while the animals showed improved physical performance, fewer signs of cellular aging, and reduced systemic inflammation. The findings have been published in the journal Metabolism.

An anonymous reader quotes a report from ScientificAmerican: After a brain stem stroke left him almost entirely paralyzed in the 1990s, French journalist Jean-Dominique Bauby wrote a book about his experiences -- letter by letter, blinking his left eye in response to a helper who repeatedly recited the alphabet. Today people with similar conditions often have far more communication options. Some devices, for example, track eye movements or other small muscle twitches to let users select words from a screen. And on the cutting edge of this field, neuroscientists have more recently developed brain implants that can turn neural signals directly into whole words. These brain-computer interfaces (BCIs) largely require users to physically attempt to speak, however -- and that can be a slow and tiring process. But now a new development in neural prosthetics changes that, allowing users to communicate by simply thinking what they want to say.

The new system relies on much of the same technology as the more common "attempted speech" devices. Both use sensors implanted in a part of the brain called the motor cortex, which sends motion commands to the vocal tract. The brain activation detected by these sensors is then fed into a machine-learning model to interpret which brain signals correspond to which sounds for an individual user. It then uses those data to predict which word the user is attempting to say. But the motor cortex doesn't only light up when we attempt to speak; it's also involved, to a lesser extent, in imagined speech. The researchers took advantage of this to develop their "inner speech" decoding device and published the results on Thursday in Cell. The team studied three people with amyotrophic lateral sclerosis (ALS) and one with a brain stem stroke, all of whom had previously had the sensors implanted. Using this new "inner speech" system, the participants needed only to think a sentence they wanted to say and it would appear on a screen in real time. While previous inner speech decoders were limited to only a handful of words, the new device allowed participants to draw from a dictionary of 125,000 words. To help keep private thoughts private, the researchers implemented a code phrase "chitty chitty bang bang" that participants could use to prompt the BCI to start or stop transcribing.

New research suggests exposure to some common Pfas or "forever chemical" compounds causes changes to gene activity, and those changes are linked to health problems including multiple cancers, neurological disorders and autoimmune disease. From a report: The findings are a major step toward determining the mechanism by which the chemicals cause disease and could help doctors identify, detect and treat health problems for those exposed to Pfas before the issues advance. The research may also point toward other diseases potentially caused by Pfas that have not yet been identified, the authors said.

The study is among the first to examine how Pfas chemicals impact gene activity, called epigenetics. "This gives us a hint as to which genes and which Pfas might be important," said Melissa Furlong, a University of Arizona College of Public Health Pfas researcher and study lead author.

alternative_right shares a report from ScienceAlert: In February 2023, a detector called KM3NeT, located deep under the Mediterranean Sea, picked up a signal that seemed to indicate a neutrino with a record-shattering energy of 220 petaelectronvolts (PeV). For reference, the previous record was a mere 10 PeV. Now, an exhaustive analysis of all the data on and around the event, designated KM3-230213A, not only supports the conclusions that the signal was caused by a 220-PeV neutrino, but adds to the mystery about where the heck in the Universe it came from."The patterns of light detected for KM3-230213A show a clear match to what is expected from a relativistic particle crossing the detector, most likely a muon, ruling out the possibility of a glitch," the KM3NeT Collaboration told ScienceAlert. "Thanks to the reconstructed energy and direction of this muon, the most likely scenario by far is that the muon originated in the interaction of an astrophysical neutrino in proximity to the detector, making it the most natural explanation."

The scientists believe that it's very, very unlikely that the neutrino originated within the Milky Way galaxy. Work is underway to come closer to tracing its origin point. "KM3-230213A opened a new window on ultra-high-energy neutrino astronomy," the Collaboration said. "Our analysis is the first effort to combine the observations of multiple telescopes over a wide energy range to characterize the ultra-high-energy spectrum. This represents our best chance to gain knowledge on the most extreme objects that populate our Universe."

The research has been published in the journal Physical Review X.

An anonymous reader shares a report: Astronomers have observed the calamitous result of a star that picked the wrong dance partner. They have documented what appears to be a new type of supernova, as stellar explosions are known, that occurred when a massive star tried to swallow a black hole with which it had engaged in a lengthy pas de deux.

The star, which was at least 10 times as massive as our sun, and the black hole, which had a similar mass, were gravitationally bound to one another in what is called a binary system. But as the distance separating them gradually narrowed, the black hole's immense gravitational pull appears to have distorted the star -- stretching it out from its spherical shape -- and siphoned off material before causing it to explode. An AI algorithm detected the event in real time, enabling astronomers to conduct comprehensive observations. Data from four years before the supernova showed bright emissions as the black hole consumed its companion's outer hydrogen layer. The exact mechanism remains uncertain -- either gravitational distortion triggered the star's collapse or the black hole completely tore it apart first. Following the explosion, the black hole consumed residual stellar debris, growing more massive.

Twenty years after Michelin introduced the Tweel in 2005, airless tires remain absent from passenger vehicles despite their promise to "eliminate nearly 200 million scrap tires a year caused by flats and underinflation," according to Michelin's internal testing cited in a Jalopnik report. Current prototypes "tend to transfer more road noise and vibration into the cabin than traditional radials -- making the ride harsher, especially at highway speeds." Heat dissipation poses additional challenges as "airless designs -- particularly those with internal webbing or solid cores -- have fewer ways to shed thermal load." The added structural mass "can affect fuel economy and increase unsprung weight -- bad news for handling and suspension tuning." Federal regulations compound these technical barriers since vehicle tires are subject to rigorous performance standards, many of which assume air pressure as a baseline.

An anonymous reader New Atlas: An engineered protein that acts like a molecular sponge has the potential to change how carbon monoxide poisoning is treated, chasing down CO molecules in the bloodstream and helping the body flush them out in just minutes, without the risk of short- or long-term health issues that come with the current frontline treatment, pure oxygen. Researchers at the University of Maryland School of Medicine (UMSOM) were focused on a natural protein known as RcoM, found in the bacterium Paraburkholderia xenovorans. In bacteria, RcoM detects trace amounts of CO in the environment, so the engineers believed this could be harnessed to scavenge for CO molecules attached to red blood cells instead.

The re-engineered protein is the basis of the therapy they call RcoM-HBD-CCC. While it's not exactly a catchy name, it possesses somewhat of a superpower when it comes to cleaning out CO. It selectively binds tightly to the poisonous CO molecules, while ignoring oxygen (O2) and other critical chemical compounds, such as blood-pressure-regulating nitric oxide (NO), in the body. [...] In mouse models, RcoM-HBD-CCC therapy was able to clear CO from the blood in minutes, with it safely flushed out of the body through urine. The engineered antidote acts like a sponge, seeking out and soaking up CO attached to red blood cells. In mice, half the CO in the bloodstream was cleared out in less than a minute, freeing the hemoglobin on the cells to once again start carrying O2.

Importantly, other experimental scavenger hemoproteins haven't been able to selectively target CO, and as a result also bind to NO – so infusions of such hemoproteins can lead to a reduction of NO in the blood, tightening blood vessels and spiking blood pressure. In the study, RcoM-HBD-CCC showed it didn't have this affinity with the vital molecule. "Unlike other protein-based treatments, we found the compound caused only minimal changes in blood pressure, which was an exciting finding and raised the potential for this new molecule to have clinical applications," said study corresponding author Dr Mark T. Gladwin, Dean of UMSOM. "This has the potential to become a rapid, intravenous antidote for carbon monoxide that could be given in the emergency department or even in the field by first-responders." The study was published in the journal Proceedings of the National Academy of Sciences (PNAS).

A countrywide study of smartphone users who relocated between US cities found that moving to more walkable environments increased daily walking by 1,100 steps on average. Stanford University researchers analyzed 248,266 days of step data from 5,424 users of the Azumio Argus smartphone app who relocated 7,447 times among 1,609 cities between March 2013 and February 2016. Participants who moved from cities at the 25th percentile of walkability to those at the 75th percentile sustained the increased activity levels for at least three months after relocation.

The additional steps consisted predominantly of moderate-to-vigorous physical activity, with large walkability increases of 49-80 points associated with about one hour per week more of such activity. The study found that 42.5% of participants met national physical activity guidelines for moderate-to-vigorous activity after moving to highly walkable locations, compared to 21.5% before relocation. Computer simulations based on the data suggest that increasing all US cities to the walkability level of Chicago or Philadelphia could result in 36 million more Americans meeting aerobic physical activity guidelines.

An anonymous reader quotes a report from the BBC: Experts at the University of Edinburgh carried out a post-mortem brain examination on 25 cats which had symptoms of dementia in life, including confusion, sleep disruption and an increase in vocalization. They found a build-up of amyloid-beta, a toxic protein and one of the defining features of Alzheimer's disease. The discovery has been hailed as a "perfect natural model for Alzheimer's" by scientists who believe it will help them explore new treatments for humans.

Dr Robert McGeachan, study lead from the University of Edinburgh's Royal (Dick) School of Veterinary Studies, said: "Dementia is a devastating disease -- whether it affects humans, cats, or dogs. Our findings highlight the striking similarities between feline dementia and Alzheimer's disease in people. This opens the door to exploring whether promising new treatments for human Alzheimer's disease could also help our ageing pets." [...]

Previously, researchers have studied genetically-modified rodents, although the species does not naturally suffer from dementia. "Because cats naturally develop these brain changes, they may also offer a more accurate model of the disease than traditional laboratory animals, ultimately benefiting both species and their caregivers," Dr McGeachan said. [...] Prof Danielle Gunn-Moore, an expert in feline medicine at the vet school, said the discovery could also help to understand and manage feline dementia. The findings have been published in the European Journal of Neuroscience.

An anonymous reader shares a report: Can deleting old emails and photos help the UK tackle ongoing drought this year? That's the hope, according to recommendations for the public included in a press release today from the National Drought Group.

There are far bigger steps companies and policymakers can take to conserve water of course, but drought has gotten bad enough for officials to urge the average person to consider how their habits might help or hurt the situation. And the proliferation of data centers is raising concerns about how much water it takes to power servers and keep them cool.

"Simple, everyday choices -- such as turning off a tap or deleting old emails -- also really helps the collective effort to reduce demand and help preserve the health of our rivers and wildlife," Helen Wakeham, Environment Agency Director of Water, said in the press release.

An anonymous reader quotes a report from MIT Technology Review: Physicists have created a new type of radar that could help improve underground imaging, using a cloud of atoms in a glass cell to detect reflected radio waves. The radar is a type of quantum sensor, an emerging technology that uses the quantum-mechanical properties of objects as measurement devices. It's still a prototype, but its intended use is to image buried objects in situations such as constructing underground utilities, drilling wells for natural gas, and excavating archaeological sites. [...] The glass cell that serves as the radar's quantum component is full of cesium atoms kept at room temperature. The researchers use lasers to get each individual cesium atom to swell to nearly the size of a bacterium, about 10,000 times bigger than the usual size. Atoms in this bloated condition are called Rydberg atoms.

When incoming radio waves hit Rydberg atoms, they disturb the distribution of electrons around their nuclei. Researchers can detect the disturbance by shining lasers on the atoms, causing them to emit light; when the atoms are interacting with a radio wave, the color of their emitted light changes. Monitoring the color of this light thus makes it possible to use the atoms as a radio receiver. Rydberg atoms are sensitive to a wide range of radio frequencies without needing to change the physical setup... This means a single compact radar device could potentially work at the multiple frequency bands required for different applications.

[Matthew Simons, a physicist at the National Institute of Standards and Technology (NIST), who was a member of the research team] tested the radar by placing it in a specially designed room with foam spikes on the floor, ceiling, and walls like stalactites and stalagmites. The spikes absorb, rather than reflect, nearly all the radio waves that hit them. This simulates the effect of a large open space, allowing the group to test the radar's imaging capability without unwanted reflections off walls.The researchers placed a radio wave transmitter in the room, along with their Rydberg atom receiver, which was hooked up to an optical table outside the room. They aimed radio waves at a copper plate about the size of a sheet of paper, some pipes, and a steel rod in the room, each placed up to five meters away. The radar allowed them to locate the objects to within 4.7 centimeters. The team posted a paper on the research to the arXiv preprint server in late June.

Researchers at Kyushu University have developed a solid-oxide fuel cell that operates at just 300C, less than half the usual operating temperature. The team was able to do this by engineering a "ScO6 highway" in the electrolyte, allowing protons to move quickly without losing performance. "The team expects that their new findings will lead to the development of low-cost, low-temperature SOFCs and greatly accelerate the practical application of these devices," said the researchers in a press release. Interesting Engineering reports: "While SOFCs are promising due to their high efficiency and long lifespan, one major drawback is that they require operation at high temperatures of around 700-800C (1292F-1472F)," added the researchers in a press release. Such heat requires costly, specialized heat-resistant materials, making the technology expensive for many applications. A lower operating temperature is expected to reduce these manufacturing costs.

The team's success comes from re-engineering the fuel cell's electrolyte, the ceramic layer that transports protons (hydrogen ions) to generate electricity. Previously, scientists faced a trade-off. Adding chemical dopants to an electrolyte increases the number of available protons but also tends to clog the material's crystal lattice, slowing proton movement and reducing performance. The Kyushu team worked to resolve this issue. "We looked for oxide crystals that could host many protons and let them move freely -- a balance that our new study finally struck," stated Yamazaki.

They found that by doping two compounds, barium stannate (BaSnO3) and barium titanate (BaTiO3), with high concentrations of scandium (Sc), they could create an efficient structure. Their analysis showed that the scandium atoms form what the researchers call a "ScO6 highway." This structure creates a wide and softly vibrating pathway through the material. "This pathway is both wide and softly vibrating, which prevents the proton-trapping that normally plagues heavily doped oxides," explained Yamazaki. The resulting material achieves a proton conductivity of more than 0.01 S/cm at 300C, a performance level comparable to conventional SOFC electrolytes that run at more than double the temperature. The research has been published in the journal Nature Materials.

Biochar produced from solid human excrement could supply up to 7% of global phosphorus fertilizer needs annually, according to a Cornell University study published in PNAS. When combined with nutrients extracted from urine, the process could provide 15% of phosphorus, 17% of nitrogen, and 25% of potassium used in agriculture worldwide.

The biochar production process reduces solid waste volume and weight by up to 90%, while allowing nutrient proportions to be adjusted for specific crop requirements.

Wedneday Beyond Meat "missed Wall Street estimates for second-quarter revenue," reports Reuters. "Consumers' growing concerns about processed foods are severely diminishing the appeal of Beyond Meat's product line, causing retailers and quick service restaurants to pull back sharply on orders," Rachel Wolff, analyst at Emarketer, said.

Retail sales of refrigerated plant-based meat alternative products in the U.S. have fallen 17.2% so far this year, and frozen plant-based meat alternatives have fallen 8.1%, according to data from SPINS... [Beyond's] revenue for the quarter ended June 28 fell nearly 20% to $75 million, compared with analysts' average estimate of $82 million, according to data compiled by LSEG.
While the company arguably invented a new market for plant-based meat substitutes, it also "owns no real intellectual property," argues The Street. "And every company in the meat and grocery business (more or less) now sells a take-off of a product that already had limited appeal..." Beyond Meat has admitted it's in trouble by hiring corporate restructuring expert John Boken from consultancy AlixPartners as interim chief transformation officer [with a focus that includes "operating expense reduction" and "broader operational efficiency"]. It has also let go of 44 employees in North America (6% of its global workforce) as it seeks to cut operating expenses amid disappointing sales... Beyond Meat also has a significant cash problem. As of June 28, 2025, Beyond Meat's cash and cash equivalents balance was $117.3 million, and total outstanding debt was $1.2 billion. The company does have time to fend off a Chapter 11 bankruptcy filing, but it also has limited, if any, prospects to meet its impending cash needs.

Imagine this. Lightning sparks a wildfire, but "within seconds, a satellite dish swirling overhead picks up on the anomaly and triggers an alarm," writes the Los Angeles Times. "An autonomous helicopter takes flight and zooms toward the fire, using sensors to locate the blaze and AI to generate a plan of attack. It measures the wind speed and fire movement, communicating constantly with the unmanned helicopter behind it, and the one behind that. Once over the site, it drops a load of water and soon the flames are smoldering. Without deploying a single human, the fire never grows larger than 10 square feet.

"This is the future of firefighting." On a recent morning in San Bernardino, state and local fire experts gathered for a demonstration of the early iterations of this new reality. An autonomous Sikorski Black Hawk helicopter, powered by technology from Lockheed Martin and a California-based software company called Rain, is on display on the tarmac of a logistics airport in Victorville — the word "EXPERIMENTAL" painted on its military green-black door. It's one of many new tools on the front lines of firefighting technology, which experts say is evolving rapidly as private industry and government agencies come face-to-face with a worsening global climate crisis...

Scientific studies and climate research models have found that the number of extreme fires could increase by as much as 30% globally by 2050. By 2100, California alone could see a 50% increase in wildfire frequency and a 77% increase in average annual acres burned, according to the state's most recent climate report. That's largely because human-caused climate change is driving up temperatures and drying out the landscape, priming it to burn, according to Kate Dargan Marquis, a senior advisor with the Gordon and Betty Moore Foundation who served as California's state fire marshal from 2007 to 2010.... "[T]he policies of today and the technologies of today are not going to serve us tomorrow."

Today, more than 1,100 mountaintop cameras positioned across California are already using artificial intelligence to scan the landscape for the first sign of flames and prompt crews to spring into action. NASA's Earth-observing satellites are studying landscape conditions to help better predict fires before they ignite, while a new global satellite constellation recently launched by Google is helping to detect fires faster than ever before.
One 35-year fire service veteran who consults on fire service technologies even predicts fire-fighting robots will also be used in high-risk situations like the Colossus robot that battled flames searing through Notre-Dame Cathedral in Paris...

And a bill moving through California's legislation "would direct the California Department of Forestry and Fire Protection to establish a pilot program to assess the viability of incorporating autonomous firefighting helicopters in the state."

"It sounds like science fiction: a spacecraft, no heavier than a paperclip, propelled by a laser beam," writes this report from ScienceDaily, "and hurtling through space at the speed of light toward a black hole, on a mission to probe the very fabric of space and time and test the laws of physics."

"But to astrophysicist and black hole expert Cosimo Bambi, the idea is not so far-fetched." Reporting in the Cell Press journal iScience, Bambi outlines the blueprint for turning this interstellar voyage to a black hole into a reality... "We don't have the technology now," says author Cosimo Bambi of Fudan University in China. "But in 20 or 30 years, we might." The mission hinges on two key challenges — finding a black hole close enough to target and developing probes capable of withstanding the journey.

Previous knowledge on how stars evolve suggests that there could be a black hole lurking just 20 to 25 light-years from Earth, but finding it won't be easy, says Bambi. Because black holes don't emit or reflect light, they are virtually invisible to telescopes... "There have been new techniques to discover black holes," says Bambi. "I think it's reasonable to expect we could find a nearby one within the next decade...."

Bambi points to nanocrafts — gram-scale probes consisting of a microchip and light sail — as a possible solution. Earth-based lasers would blast the sail with photons, accelerating the craft to a third of the speed of light. At that pace, the craft could reach a black hole 20 to 25 light-years away in about 70 years. The data it gathers would take another two decades to get back to Earth, making the total mission duration around 80 to 100 years... Bambi notes that the lasers alone would cost around one trillion euros today, and the technology to create a nanocraft does not yet exist. But in 30 years, he says that costs may fall and technology may catch up to these bold ideas.
"If the nanocraft can travel at a velocity close to the speed of light, the mission could last 40-50 years," Bambi writes in the article, while acknowledging his idea is certainly very speculative and extremely challenging..."

"However, we should realize that most of the future experiments in particle physics and astrophysics will likely require long time (for preparation, construction, and data collection) and the work of a few generations of scientists, be very expensive, and in many cases, we will not have other options if we want to make progress in a certain field."

The BBC reports: A meteorite that crashed into a home in the U.S. is older than planet Earth, scientists have said...

Researchers at the University of Georgia examined a fragment of the rock that pierced the roof of a home in the city of McDonough [30 miles south of Georgia, on June 26]. They found that, based on the type of meteorite, it is expected to have formed 4.56 billion years ago, making it roughly 20 million years older than Earth... The rock quickly diminished in size and speed, but still travelled at least 1 km per second, going through a man's roof in Henry County...

Using optical and electron microscopy, Scott Harris [a Univeristy of Georgia geologist] and his team determined the rock was a chondrite — the most abundant type of stony meteorite, according to NASA — which meant that it was approximately 4.56 billion years old.
"The home's resident said he is still finding pieces of space dust around his home from the hit."

After five months on the International Space Station, four astronauts splashed down in the Pacific Ocean in a SpaceX Crew Dragon capsule named Endurance, reports Space.com.

It was NASA's 10th commercial crew rotation mission: The flight launched atop a SpaceX Falcon 9 rocket on March 14 and arrived at the orbiting lab two days later. Crew-10's four astronauts soon set to conducting science work, which consumed much of their time over the ensuing months... The wheels for Crew-10's departure began turning last Saturday (Aug. 2), when SpaceX's four-person Crew-11 mission arrived at the International Space Station. The Crew-10 astronauts spent a few days advising their replacements, then set their minds to gearing up for the return to Earth — and reflecting on their orbital experience.

"We got to accomplish a lot of really amazing operational things," Ayers said during a farewell ceremony on Tuesday (Aug. 5). "We got to see some amazing views, and we have had some really big belly laughs and a wonderful time together," she added. "I think that [we're] leaving with a heart full of gratitude, and [we're] excited to see where the International Space Station goes after we get home." The hatches between Endurance and the ISS closed on Friday (Aug. 8) at 4:20 p.m. EDT (2020 GMT), and the capsule undocked about two hours later, at 6:15 p.m. EDT (2205 GMT). Endurance then began maneuvering its way back to Earth, setting up its splashdown today.

It was the first Pacific Ocean return for a SpaceX CCP mission; all previous such flights have come down off the Florida coast. SpaceX recently shifted to West Coast reentries for all of its Dragon missions, both crewed and uncrewed, to minimize the chance that falling space debris could damage property or injure people.
"During their mission, crew members traveled nearly 62,795,205 million miles," NASA announced, "and completed 2,368 orbits around Earth..." Along the way, Crew-10 contributed hundreds of hours to scientific research, maintenance activities, and technology demonstrations. McClain, Ayers, and Onishi completed investigations on plant and microalgae growth, examined how space radiation affects DNA sequences in plants, observed how microgravity changes human eye structure and cells in the body, and more. The research conducted aboard the orbiting laboratory advances scientific knowledge and demonstrates new technologies that enable us to prepare for human exploration of the Moon and Mars.

McClain and Ayers also completed a spacewalk on May 1, relocating a communications antenna, beginning the installation of a mounting bracket for a future International Space Station Roll-Out Solar Array, and other tasks.