Artificial intelligence is to be used to tackle the most deadly parasitic diseases in the developing world, tech company DeepMind has announced. The BBC reports: The London-based Alphabet-owned lab will work with the Drugs for Neglected Diseases initiative (DNDI) to treat Chagas disease and Leishmaniasis. Scientists spend years in laboratories mapping protein structures. But last year, DeepMind's AlphaFold program was able to achieve the same accuracy in a matter of days. Many diseases are linked to the roles of proteins in: catalysing chemical reactions (enzymes); fighting disease (antibodies); and acting as chemical messengers (hormones such as insulin). And knowing the 3D structure of a protein is important in developing treatments for, among others, cancer, dementia and infectious diseases.

Prof Dame Janet Thornton, of the European Bioinformatics Institute, told BBC News: "Most new drugs in recent years have been developed using protein-structural data as one part of the process. "There are, however, many other aspects which need to be taken into account, which, due to lack of data, may not be amenable to AI approaches." But the predictions would be "particularly valuable" for pathogens with unknown protein structures, including some neglected diseases. "Developing new AI approaches for designing such drugs is a new challenge but one to which the new AI techniques can be applied and this holds out great hope for the future," Dame Janet added.

An anonymous reader quotes a report from Bloomberg: Amazon won a Texas trial in which it was accused of incorporating an Israeli company's patented "smart kitchen" inventions for voice commands to shop for groceries online into the Alexa digital assistant. Amazon didn't infringe three patents owned by closely held Ikan Holdings LLC's Freshub unit, the federal jury in Waco, Texas, said Tuesday. Freshub said its inventions allow consumers to create shopping lists, establish a shopping cart and order from their local grocer by using voice commands or scanning bar codes of products with an internet-connected device. Amazon knew of Freshub and its patents when it incorporated the technology into its Alexa assistant and Echo smart speakers, and promoted it for use with its Whole Foods grocery chain, Freshub claimed.

Amazon accused the company of manipulating patent applications to ensure they covered Alexa and Echo after the popular products had already entered the market. Amazon also warned jurors that a victory for Freshub would mean more lawsuits by the company against other tech firms like Apple and Google. Freshub argued consumers using the technology spent more money, so it was entitled to $3.50 per unit sold with the functionality, for a total of $246 million. Amazon argued that the patents were worth at most $1 million.

Kickstarter announced Tuesday that it plans to experiment with a four-day work week in an effort to offer workers more flexibility and additional time to spend on creative pursuits. From a report: Lots of tech companies are planning to offer flexibility around where employees work post-pandemic. Now some companies are also rethinking when people work. Kickstarter plans next year to test a four-day work week with some or all of its employees, though details of that remain to be figured out, including whether all workers will have the same schedule. Dating app Bumble, meanwhile, says it's giving all employees this week off to allow a much-needed break. Kickstarter CEO Aziz Hasan told Axios that he had toyed with the notion of a four-day week in the past, but was motivated by the pandemic to actually give it a try. "What we've been all living through the last 18 months, you feel this compression on your professional life, your personal life," Hasan said. The idea of a four-day work week wasn't spurred by the company's ongoing collective bargaining negotiations, Hasan said. He added that the company's newly formed union has been supportive of the idea.

Tim Berners-Lee has defended his decision to auction an NFT (non-fungible token) representing the source code to the web, comparing the sale to an autographed book or a speaking tour. From a report: The creator of the world wide web announced his decision to create and sell the digital asset through Sotheby's auction house last week. In the auction, which begins on Wednesday and will run for one week, collectors will have the chance to bid on a bundle of items, including the 10,000 lines of the source code to the original web browser, a digital poster created by Berners-Lee representing the code, a letter from him, and an animated video showing the code being entered.

"This is totally aligned with the values of the web," Berners-Lee told the Guardian. "The questions I've got, they said: 'Oh, that doesn't sound like the free and open web.' Well, wait a minute, the web is just as free and just as open as it always was. The core codes and protocols on the web are royalty free, just as they always have been. I'm not selling the web -- you won't have to start paying money to follow links. "I'm not even selling the source code. I'm selling a picture that I made, with a Python programme that I wrote myself, of what the source code would look like if it was stuck on the wall and signed by me. "If they felt that me selling an NFT of a poster is inappropriate, then what about me selling a book? I do things like that, which involve money, but the free and open web is still free and open. And we do still, every now and again, have to fight to keep it free and open, fight for net neutrality and so on."