Follow Slashdot blog updates by subscribing to our blog RSS feed

 



Forgot your password?
typodupeerror
United States Science

US Approves CRISPR Pigs For Food (technologyreview.com) 54

The FDA has approved gene-edited pigs for human consumption, potentially marking the first major commercial application of CRISPR technology in the food chain. Created by British company Genus, these pigs have had their DNA modified to remove the receptor that the porcine reproductive and respiratory syndrome (PRRS) virus uses to enter cells, rendering them immune to 99% of known virus variants.

PRRS causes losses of approximately $300 million annually in the US alone by killing piglets and spreading rapidly through factory farms. According to Matt Culbertson, chief operating officer of Genus subsidiary Pig Improvement Company, the gene-edited pork could reach US markets sometime next year. Before launching sales to pig farms, Genus must secure regulatory approval in key export markets including Mexico, Canada, Japan, and China.

US Approves CRISPR Pigs For Food

Comments Filter:
  • by davidwr ( 791652 ) on Friday May 02, 2025 @02:08PM (#65347839) Homepage Journal

    Mmmm, genetically modified bacon, mmmmmm.

    • Unironically yes, GMO's and CRISPR food science is cool as shit imo and should be considered an advantage if it cuts down the use of herbicides and pesticides and it makes things cheaper and potentially better in a lot of ways. We all learned the maize to corn story. More tomato? [youtube.com]

      • by Rinnon ( 1474161 )
        I generally agree, though I always wonder what problem we'll have caused by, in this case for example, removing that receptor.
        • by EvilSS ( 557649 )
          What problems could it cause that actually matter though? These are livestock and not wild animals with the possibility of some long-tail repercussions to the overall ecology down the road. As long as they can reproduce as needed, grow to the expected size, and stay healthy long enough to make it to slaughter, what else is there?
          • by Rinnon ( 1474161 )

            What problems could it cause that actually matter though? These are livestock and not wild animals with the possibility of some long-tail repercussions to the overall ecology down the road. As long as they can reproduce as needed, grow to the expected size, and stay healthy long enough to make it to slaughter, what else is there?

            What problems could it cause? I mean, that's exactly the thing I wonder about. Maybe it will cause unforeseen problems down the line that will impact their ability to "reproduce as needed, grow to the expected size, and stay healthy long enough to make it to slaughter". I'm not saying that means it's bad, or we shouldn't do it, I just figure that when it comes to making genetic modifications there's a good chance we're not able to simulate every possible consequence beforehand.

            • I think these are valid concerns, but I think gene editing is strictly better than random mutations, and we are doing literally nothing about random mutations.

          • These are livestock and not wild animals with the possibility of some long-tail repercussions to the overall ecology down the road.

            Sure as long as they stay livestock. Just look at the wild boar issue in Texas to see how that can become problematic. Pigs can and will eat just about anything, breed quickly, and are fairly smart.

            Plus they don't really have a lot of natural predators in many countries. Wolves and mountain lions are 2 of the 3 predators in the US that can take on an adult hog. But their numbers are too few to make a dent. Bears being the other. But boars can live in places bears don't do well. The UK has no predators

          • Greenpeace is concerned that the pigs will turn into Frankenstein's zombies and eat all of the whales into extinction, because nobody anywhere on the planet knows how proteins work and the unknown is to be feared and avoided at all costs, even if it means every Asian kid goes blind

        • CRISPieR pork rinds.
      • by djinn6 ( 1868030 )

        It should be. However, you first have to trust the government organizations responsible for vetting it. I think it's pretty clear at this point that a lot of people have been bought off by various business interests and care more about lining their own pockets rather than public health.

        • As they should! Caveat Emptor is the watchword of any free society!

        • This is the same government that inspects your non-GMO food. If you're not already skeptical about what you're getting I don't see how this should change anything for you.
          • by djinn6 ( 1868030 )

            Non-GMO businesses don't stand to gain anything from the government not doing its job. If I were a lettuce grower, I'd want the government to do its inspections correctly and prevent e.g. a salmonella outbreak turning customers away from lettuce.

            Meanwhile, if I ran a company that did GMO research, then the government is the difference between making zero money and making hundreds of millions. Paying off a few people to the tune of a few million each would be well worth the cost.

      • by Random361 ( 6742804 ) on Friday May 02, 2025 @02:47PM (#65347945)

        IIRC, one of the arguments against Monsanto's genetic modification of crops was that they effectively made them resistant to glyphosate-based herbicides like Roundup. This allowed them to then spray the cancer-causing herbicide all over everyone's food. They also engineered lines of crops that produced sterile seeds, guaranteeing that farmers would have to keep coming back to the company for each crop. This probably shouldn't come as a surprise, though, as Monsanto was also the genius behind DDT, and Agent Orange. At least these guys brought LEDs to market. They were bought by Bayer in 2016 in what is considered one of the worst corporate mergers in history.

        In this case, using CRISPR to knock out the receptor PRRS uses, making the pigs immune to it. Similar things have been proposed to knock out CCR-5 in humans, conveying immunity to HIV for a similar reason. Now, what effects it might have on the pigs is a different question, but it isn't going to make the pigs poisonous or something. It wasn't the genetic modification that was the problem back with the crops, it was the fact that Monsanto was a bunch of greedy crooks and used genetic modification to enable them to carpet bomb the world's food with glyphosate.

        • Yeah I think unfortunately that's the more likely the scenario of really good and useful tech but wielded by the worst behaving corporate interests. Like roundup resistant crops is actually quite a good idea and it works from the perspective of the science but those negatives were the lawsuits and forced sterility since now it was made into a subscription mode. The science worked

          I remember reading the outcome of that case and I believe the cancer contention never came through the data in terms of general

        • IIRC, one of the arguments against Monsanto's genetic modification of crops was that they effectively made them resistant to glyphosate-based herbicides like Roundup. This allowed them to then spray the cancer-causing herbicide all over everyone's food.

          Does it actually cause cancer though?

          The consensus among national pesticide regulatory agencies and scientific organizations is that labeled uses of glyphosate have demonstrated no evidence of human carcinogenicity. The Joint FAO/WHO Meeting on Pesticide Residues (JMPR), the European Commission, the Canadian Pest Management Regulatory Agency, the Australian Pesticides and Veterinary Medicines Authority and the German Federal Institute for Risk Assessment have concluded that there is no evidence that gly

          • by djinn6 ( 1868030 )

            Did all those studies come before or after glyphosate use was approved?

            • Both? It's been around since the 70's and is pretty crucial to a lot of industries, I have to imagine this is one of the most studied substances we have.

          • Yes it does cause health problems. Proof that someone's cancer came from their pesticide? That's nearly impossible to prove because there's so many toxic things in the world and it's nearly impossible to isolate everything.

            labeled uses of glyphosate have demonstrated

            That's the first redirection. Labeled uses. In practice almost no one applies it as labeled because doing so is so difficult. Roundup is sold in stores like Home Depot. You can avoid it all you want by shopping extremely carefully but if your neighbor misapplies it, which they will,

      • They should have approved the genetically modified salmon that have been around for a while now. Letting natural populations of fish recover is more important than having cheaper pork. We should look into extending it to other fish populations as well.
    • Re: (Score:2, Funny)

      by rwrife ( 712064 )
      I'm sure someone asked Trump about this and he was like "yes, I love crispy bacon".
    • And square [youtu.be]

    • Crispy CRISPR pork scratchings. Mine's a pint of best, if you're in the chair.

    • If Crispr brand bacon is trademark-able they should certainly do it.
  • by dynamo ( 6127 ) on Friday May 02, 2025 @02:11PM (#65347851) Journal

    US exports are pretty much over, at least for the next 3.7 years. They might as well release now.

    • TIL that Mexicans love American pigs. I've always been told that China is one of our top markets, but they're only #3. Source https://www.porkcheckoff.org/markets/us-pork-exports/ [porkcheckoff.org]. It's pretty weird that China can't produce enough pigs to feed their people. I thought the point of pigs is that they're easy to raise and can live off anything. I know the USA is one of the very best at agricultural practices, worldwide...but you'd think pigs would be much cheaper to raise in Mexico and China.
      • China isn't blessed with much arable cropland. Pigs eat quite a bit.

        Their dependence on rice patties is an example of a workaround.

        Bonus: they're farming crayfish with the rice now which makes more food and almost eliminates some chemical herbicide and pesticide use.

        Crayfish is delicious. Fresh - frozen isn't too good but if you're near a bayou in the Spring by all means eat to excess.

      • It's pretty weird that China can't produce enough pigs to feed their people.
        They can.
        But they are good capitalists, and buy what is cheap on the market.

        And if you look at your link, a 1.7billion population imports pork for 9million dollars. That is about one bite from a burger per person.

  • arrggllhelehhargglehhge...
  • Considering how anti-science he is, one would think he would be wholly against this.

    For all we know this gene editing might cause autism. /s

    • Does it mean that the new pigs won;t need as many vaccines ?
    • You're assuming that he's paying attention to everything happening in his department he's allegedly running. We've already seen several examples of his department announcing things that he's not aware of, usually cuts of things like child cancer research. And then he does his bobblehead routine where he arglebargles for a bit and then says "he'll look into it"

      Spoiler: he will not look into it. He just doesn't have time for that shit between his shameless self-promotion and his 6-month promise to finally

      • You're assuming that he's paying attention to everything

        You're assuming that he has any attention left to pay to anything. Apart from getting (or resisting) his next smack fix.

        4 crates left of the Ark, according to the Russian map of the top secret store. Hegseth gave them the plans.

      • Spoiler: he will not look into it. He just doesn't have time for that shit between his shameless self-promotion and his 6-month promise to finally shed the light on the causes of autism, once and for all - as if it's sitting in an filing cabinet in that warehouse at the end of Indiana Jones, and all they need to do is find it.

        Nah, the autism thing isn't taking any time at all. He -- and everyone else -- already knows the conclusion. The only reason he pushed it out until September was to allow him to at least pretend the conclusion wasn't foregone. Well, probably also so his buddy David Geier, noted anti-vaxxer who was once prosecuted for practicing medicine without a license, can collect a government paycheck for a while. But in due course they'll publish the astonishing conclusion that vaccines cause autism. Without any rea

    • Yes, requiring placebo-controlled trials for drugs is an exemplar of being anti-science.

      It's amazing that some people remember to breathe.

  • Caffeinated bacon? Baconated grapefruit?

    Admiral Crunch??

  • Replace it with a very specific fix for a narrow problem.

    The money that they save by reducing pre-slaughter food hygiene will increase the frequency of salmonella outbreaks on the farm, speed the cross-contamination between pigs and passing wild birds (particularly the expensive "happy pig" brands) and won't do anything to prevent human pathogens form sewage sludge fertilisers getting into the pigs. All of which will mean the product never gets onto any other country's plates.

    Coming next : chlorinated bac

    • Where did you get the idea that pre-slaughter food hygiene is being reduced? I'm pretty sure farmers don't get to relax just because they have a new tool to fight disease. Disease has a way of adapting.

      • History tells us that's what'll happen. It's been done with chicken and bacon. Specifically for bacon, it's the use of sodium nitrates (and celery powder/juice and sea salt) for curing. Eating sodium nitrates increases your risk of colon cancer by 2%. This is known and understood by everyone. The evidence is clear and not in dispute. We used to use nitrates directly and that just flat out killed people if you used a little too much. Prior to that we used more natural methods which were safe but took

America has been discovered before, but it has always been hushed up. - Oscar Wilde

Working...