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Science

First British Baby Born Using Transplanted Womb From Dead Donor (bbc.com) 70

A 10-week-old boy named Hugo has become the first baby born in the UK from a womb transplanted from a deceased donor, after his mother Grace Bell -- who was born without a viable womb due to a condition called MRKH syndrome, which affects one in every 5,000 women -- underwent a 10-hour transplant operation at The Churchill Hospital in Oxford in June 2024.

Hugo was born just before Christmas 2025, weighing nearly 7lbs, at Queen Charlotte's and Chelsea Hospital in west London, following IVF treatment and embryo transfer at The Lister Fertility Clinic. Bell's transplant is one of three completed so far as part of a UK clinical research trial that plans to carry out 10 such procedures from deceased donors, and Hugo is the first baby born from any of them.
Earlier in 2025, a separate effort produced baby Amy, the first UK birth from a living womb donation -- her mother had received her older sister's womb in January 2023. Globally, more than 100 womb transplants have been performed, resulting in over 70 healthy births.
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First British Baby Born Using Transplanted Womb From Dead Donor

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  • by robi5 ( 1261542 ) on Tuesday February 24, 2026 @09:53PM (#66008998)

    How? Was he 10 weeks old already when he was born? Or did he reach 7lbs from conception and was born prematurely after 10 weeks of pregnancy? Or was he not going to be the first such baby, and then 10 weeks after he was born, he became the first somehow?

    • by sjames ( 1099 )

      Or he weighed 7 lbs at birth back in December and he is now 10 weeks old.

    • Honestly the way they word it sounds like he's the first to have the womb donor die. But that\s only an accomplishment if he killed her.

      • by Rei ( 128717 )

        Amusing comment ;) But from a more serious perspective: uterus transplants from living donors are much easier, but they're also in much lower supply.

  • Why would you do this to a kid? It's first and foremost a huge risk, because the transplant could be rejected during the pregnancy. Then the kid is going to be dosed with all the drugs required by any transplant patient.
    • Re: (Score:2, Interesting)

      by Anonymous Coward

      hey buddy... you might want to look at the function of the placenta

      A regular baby is already a foreign body inside a mother. Why does the mother's immune system not attack them? Why does the baby's not attack the mother?

      This probably isn't that much more risk to the child than being born by c-section.

    • by Rei ( 128717 ) on Wednesday February 25, 2026 @07:10AM (#66009318) Homepage

      People have been having children while on immunosuppressants since cortisone was released in 1949. Many millions of children. The science supports that having children while on immunosuppressants is safe for the child. And I guarantee you, this is the first thing everyone looking into this procedure asks themselves, as well as every doctor, nurse and researcher in the field.

      • People have been having children while on immunosuppressants since cortisone was released in 1949. Many millions of children. The science supports that having children while on immunosuppressants is safe for the child. And I guarantee you, this is the first thing everyone looking into this procedure asks themselves, as well as every doctor, nurse and researcher in the field.

        FTA: "Globally, more than 100 womb transplants have been performed, resulting in over 70 healthy births."

        That's about a 33 percent failure rate (and to tell with the "over" business. Were people experiencing unhealthy births, stillborns?

        And let's not forget the six or more births at a time that was a media trend some years back. A lot of those children were developmentally messed up, physically or intellectually. Yeah, no - the urge to bear children and cause people to go into this knowing the outcome

        • by Rei ( 128717 )

          That's about a 33 percent failure rate

          Do I seriously need to explain to you how to read English? Or in your mind, is there some law that says "one womb transplant = one birth"?

          • by Rei ( 128717 )

            On reflection, my wording was too harsh for what was a simple misreading on your part. But just to be clear: some recipients have multiple children. Some have just one. But most have none, and the most common reason is rejection of the transplant. They don't even try IVF until they're certain the transplant isn't being rejected (traditionally at least a 12 month wait, though times have been dropping). 25-30% of transplants fail before IVF can be attempted. Each IVF cycle has ~50% odds for a young woman

            • by Rei ( 128717 )

              ED: but many have none

            • On reflection, my wording was too harsh for what was a simple misreading on your part.

              No problem - happens a lot. But really, it wasn't misreading. It was wondering what the specific issues caused that failure rate. I immediately become very curious. I'm a troubleshooter. And if we only hear part of the story, maybe paying attention to the failures and fixing the failures will increase the success rate.

              Anyhow, I am different than most people. When I get half the story, I want the rest of it! 8^)

  • Livelong immunosuppressants for something you only need for a few years seems out of proportion for me.

    • Maybe they can remove the transplant after the function has been fulfilled, or when the receiver reaches menopause age.

    • by mudimba ( 254750 )

      The article said the couple are considering having another baby, but when they are ready to stop the mother will have the transplant womb removed. She only needs to take the drugs for as long as they are planning on having children.

    • by Rei ( 128717 )

      As was pointed out, not lifelong - and also, FYI, surrogacy is not only very expensive and leaves you without the experience of having carried your child, but it's also illegal in many places.

    • Agreed. If there's a legal issue, it seems like the safer route to fix the law. It's a lot of money and risked health just to carry a baby.

  • Because this comes with severe risks and takes a lot of resources. Seems to me the transplant recipient is getting exploited and valuable medical resources get squandered.

    If you really need offspring that inherits your genetic problems, a surrogate mother would be a far better choice. If not, adopt. There are a lot of kids that are already around and would benefit from a good family.

    • Because this comes with severe risks and takes a lot of resources. Seems to me the transplant recipient is getting exploited and valuable medical resources get squandered.

      If you really need offspring that inherits your genetic problems, a surrogate mother would be a far better choice. If not, adopt. There are a lot of kids that are already around and would benefit from a good family.

      I agree. I have a lot of ethical questions. One of the big ones is that success rate doesn't give me the warm fuzzies. And in a public healthcare system, it indeed is a squandering of resources.

      Dare I say some of these things seem a little cruel for women? IVF sounds nice, until you see the regimen the woman has to go through, the expense, and the not so great success rate. And for some, a 10 hour operation, messing with anti rejection drugs that carry their own issues, So yet another cruel hope for wome

  • This is the grossest Slashdot headline that I've ever read.

    Never before has a Slashdot headline repulsed me so deeply.

  • What makes me scratch my head is that there are many brilliant medical people apparently working on this. If they were working on a (type of) cancer cure, maybe thousands of lives would be saved because said cure would come sooner.

"If value corrupts then absolute value corrupts absolutely."

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