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This Virus Stole a Human Gene and Won't Let Go of It (phys.org) 26

Posted by EditorDavid from the borrowing-a-pair-of-genes dept.
"Scientists have discovered a virus that is a tiny bit human, carrying a gene it stole from our ancestors about 100,000 years ago," writes the New York Times. "And this virus may be using our own gene to infect us."

Phys.org explains that it's "both an important gene for brain function and a jumping gene capable of moving and inserting itself into genomes." BC200 is found only in humans and related primates and was discovered in the late 1980s as an abundant noncoding RNA in human neurons. Although BC200's physiological function is poorly understood, evidence suggests it may be involved in regulating the translation of neuronal messenger RNAs into proteins... The researchers also suspect that BC200 jumped in skin cells because these are the only cells known to be infected by molluscum contagiosum virus (MCV). The gene is also abnormally expressed in some tumors and overexpressed in the brains of patients with Alzheimer's disease, suggesting its jumping ability could play roles in these diseases.

[Cedric Feschotte, a senior author of the study] said he and his colleagues would like to explore whether the molluscum contagiosum virus uses BC200 to manipulate human host cells. They are also interested in better understanding the gene's role in disease, including breast and other types of tumors in which it is abnormally expressed, and whether it jumps in cancer cells and causes mutations.
Thanks to Slashdot reader joshuark for sharing the news.
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