fjo3 shares a report from the Washington Post: The International Space Station had to fire thrusters from a docked spacecraft last month to avoid a piece of debris that has been circling the globe for the nearly 18 years since the Chinese government blasted apart one of its own satellites in a weapons test. The evasive maneuver was the second in just six days for the space station, which has four NASA astronauts and three Russian cosmonauts aboard. That is the shortest interval ever between such actions, illustrating the slowly worsening problem of space junk in orbit. Debris is an increasingly vexing issue not only for NASA, but also for companies such as SpaceX and OneWeb seeking to protect the thousands of small satellites they send into space to provide high-speed internet. The debris cloud from China's 2007 destruction of the Fengyun 1C satellite remains one of the most persistent threats in orbit, with about 3,500 fragments still posing collision risks to spacecraft. Since 2020, the ISS has performed 15 debris-avoidance maneuvers.

The evasive maneuver was performed after a Space Force warning. According to the report, Space Force now tracks over 47,200 objects in orbit, issuing approximately 23 daily collision warnings -- up from just six per day five years ago.

An anonymous reader shared this report from Health magazine: "Most people think of aging as occurring gradually, constantly, and linearly," senior study author Michael Snyder, PhD, a professor of genetics and director of the Center for Genomics and Personalized Medicine at Stanford University, told Health. But "we're not just changing gradually over time; there are some really dramatic changes," Snyder said in a news release. "It turns out the mid-40s is a time of dramatic change, as is the early 60s. And that's true no matter what class of molecules you look at."

And these molecular changes aren't insignificant to our health — they were seen in molecules related to cardiovascular disease, skin and muscle health, immune regulation, and kidney function, among others... [R]esearchers from Stanford University and Nanyang Technological University in Singapore used data from 108 participants between the ages of 25 and 75. Those participants donated blood and other biological samples (stool samples, oral and nasal swabs) every few months over the course of several years. From those samples, researchers were able to track age-related changes in more than 135,000 different molecules and microbes in the participants' bodies.

The analysis showed that the majority of molecules and microbes underwent major changes in their abundance (increasing or decreasing) during two time periods: when people were in their mid-40s and early 60s... The molecules that showed extreme changes in a person's 40s, for example, were related to alcohol, caffeine, and lipid metabolism, as well as cardiovascular disease and skin and muscle health. Meanwhile, molecular changes in a person's 60s were related to carbohydrate and caffeine metabolism, immune regulation, kidney function, cardiovascular disease, and skin and muscle health. According to experts, these changes might show up as a reduced ability to metabolize caffeine and alcohol, suggesting that it may be wise to cut back on those substances. People in their 40s and 60s may also see a greater risk of developing cardiovascular disease, and people in their 60s may benefit from supporting their immune systems.
The article ends with this advice from Dr. Ronald DePinho, a cancer biology professor at the University of Texas's cancer center: there's ways to manage or slow some of the changes associated with aging.

"The easiest way to do that is through lifestyle changes, said DePinho — that means staying active, eating and sleeping well, managing stress, and avoiding smoking and excessive alcohol."

"Sixty-six million years ago, all dinosaurs (except for birds) were wiped from the face of the Earth..." writes Gizmodo. "What's indisputable about this pivotal moment in Earth's history is that a 6.2 to 9.3-mile-wide (10 to 15-kilometer) asteroid struck what is now modern-day Mexico. Around the same time, however, volcanoes in what is now India experienced some of the largest eruptions in Earth's history."

Those volcanos "have long been proposed as an alternative cause for the demise of the dinosaurs..." writes Phys.org. But "Now, climate scientists from Utrecht University and the University of Manchester show that while the volcanism caused a temporary cold period, the effects had already worn off thousands of years before the meteorite impacted." Earth scientists have fiercely debated for decades whether a massive outpouring of lava on the Indian continent, which occurred both prior to and after the meteorite impact, also contributed to the demise of dinosaur populations roaming Earth. These volcanic eruptions released vast amounts of CO2, dust, and sulfur, thereby significantly altering the climate on Earth — but in different ways and on different timescales to a meteorite impact. The new publication provides compelling evidence that while the volcanic eruptions in India had a clear impact on global climate, they likely had little to no effect on the mass extinction of the dinosaurs.

By analyzing fossil molecules in ancient peats from the United States of America, the scientific team reconstructed air temperatures for the time period covering both the volcanic eruptions and the meteorite impact. Using this method, the researchers show that a major volcanic eruption occurred about 30,000 years before the meteor impact, coinciding with at least a 5 degrees Celsius cooling of the climate... Importantly, the scientists discovered that by around 20,000 years before the meteorite impact, temperatures on Earth had already stabilized and had climbed back to similar temperatures before the volcanic eruptions started.
The study is published in the journal Science Advances. And Gizmodo shares this quote from Bart van Dongen of The University of Manchester, who worked on the research.

"The study provides vital insights not only into the past but could also help us find ways for how we might prepare for future climate changes or natural disasters."

The world's first nuclear-powered battery — a diamond with an embedded radioactive isotope — could power small devices for thousands of years, according to scientists at the UK's University of Bristol.

Long-time Slashdot reader fahrbot-bot shared this report from LiveScience: The diamond battery harvests fast-moving electrons excited by radiation, similar to how solar power uses photovoltaic cells to convert photons into electricity, the scientists said.

Scientists from the same university first demonstrated a prototype diamond battery — which used nickel-63 as the radioactive source — in 2017. In the new project, the team developed a battery made of carbon-14 radioactive isotopes embedded in manufactured diamonds. The researchers chose carbon-14 as the source material because it emits short-range radiation, which is quickly absorbed by any solid material — meaning there are no concerns about harm from the radiation. Although carbon-14 would be dangerous to ingest or touch with bare hands, the diamond that holds it prevents any short-range radiation from escaping. "Diamond is the hardest substance known to man; there is literally nothing we could use that could offer more protection," Neil Fox, a professor of materials for energy at the University of Bristol, said in the statement...

A single nuclear-diamond battery containing 0.04 ounce (1 gram) of carbon-14 could deliver 15 joules of electricity per day. For comparison, a standard alkaline AA battery, which weighs about 0.7 ounces (20 grams), has an energy-storage rating of 700 joules per gram. It delivers more power than the nuclear-diamond battery would in the short term, but it would be exhausted within 24 hours. By contrast, the half-life of carbon-14 is 5,730 years, which means the battery would take that long to be depleted to 50% power....

[A] spacecraft powered by a carbon-14 diamond battery would reach Alpha Centauri — our nearest stellar neighbor, which is about 4.4 light-years from Earth — long before its power were significantly depleted.
The battery has no moving parts, according to the article. It "requires no maintenance, nor does it have any carbon emissions."

"Voyager 1 is currently exploring interstellar space at a distance of 15.5 billion miles (24.9 billion kilometers) away from Earth," writes Gizmodo.

And yet a team of amateur astronomers in the Netherlands was able to receive Voyager's signals on a 1950s-era telescope... The astronomers used orbital predictions of Voyager 1's position in space to correct for the Doppler shift in frequency caused by the motion of Earth, as well as the motion of the spacecraft through space... [The signal] was found live, and further analysis later confirmed that it corresponded to the position of Voyager 1.
"I did the experiment," mathematician/scientific software engineer Tammo Jan Dijkema told Slashdot in an email, as "one of a crew of four." He works at ASTRON (the Netherlands Institute for Radio Astronomy) while volunteering at the Dwingeloo radio telescope, and wants to clarify any suggestion in Gizmodo's article "that we received signals at S-band, which is not true. We received the 'normal' Voyager-1 signal at 8.4 GHz. See our blog post... The Dwingeloo reception was not related to Voyager's temporary glitch at all."

And Scientific American shares an interesting perspective on the Voyager probes: we everyday Earthlings may simplistically think of the sun as a compact distant ball of light, in part because our plush atmosphere protects us from our star's worst hazards. But in reality the sun is a roiling mass of plasma and magnetism radiating itself across billions of miles in the form of the solar wind, which is a constant stream of charged plasma that flows off our star. The sun's magnetic field travels with the solar wind and also influences the space between planets. The heliosphere grows and shrinks in response to changes in the sun's activity levels over the course of an 11-year cycle... [Jamie Rankin, a space physicist at Princeton University and deputy project scientist of the Voyager mission] notes, astronomers of all stripes are trapped within that chaotic background in ways that may or may not affect their data and interpretations. "Every one of our measurements to date, until the Voyagers crossed the heliopause, has been filtered through all the different layers of the sun," Rankin says.

On their trek to interstellar space, the Voyagers had to cross a set of boundaries: first a termination shock some seven billion or eight billion miles away from the sun, where the solar wind abruptly begins to slow, then the heliopause, where the outward pressure from the solar wind is equaled by the inward pressure of the interstellar medium. Between these two stark borders lies the heliosheath, a region where solar material continues to slow and even reverse direction. The trek through these boundaries took Voyager 1, the faster of the twin probes, nearly eight years; such is the vastness of the scale at play.

Beyond the heliopause is interstellar space, which Voyager 1 entered in 2012 and Voyager 2 reached in 2018. It's a very different environment from the one inside our heliosphere — quieter but hardly quiescent. "It's a relic of the environment the solar system was born out of," Rankin says of the interstellar medium. Within it are energetic atomic fragments called galactic cosmic rays, as well as dust expelled by dying stars across the universe's eons, among other ingredient.
Earlier this month Wired noted " The secret of the Voyagers lies in their atomic hearts: both are equipped with three radioisotope thermoelectric generators, or RTGs — small power generators that can produce power directly on board. Each RTG contains 24 plutonium-238 oxide spheres with a total mass of 4.5 kilograms..." But as time passes, the plutonium on board is depleted, and so the RTGs produce less and less energy. The Voyagers are therefore slowly dying. Nuclear batteries have a maximum lifespan of 60 years. In order to conserve the probes' remaining energy, the mission team is gradually shutting down the various instruments on the probes that are still active...

Four active instruments remain, including a magnetometer as well as other instruments used to study the galactic environment, with its cosmic rays and interstellar magnetic field. But these are in their last years. In the next decade — it's hard to say exactly when — the batteries of both probes will be drained forever.

Nature magazine reports that "A study that stoked enthusiasm for the now-disproven idea that a cheap malaria drug can treat COVID-19 has been retracted — more than four-and-a-half years after it was published." Researchers had critiqued the controversial paper many times, raising concerns about its data quality and an unclear ethics-approval process. Its eventual withdrawal, on the grounds of concerns over ethical approval and doubts about the conduct of the research, marks the 28th retraction for co-author Didier Raoult, a French microbiologist, formerly at Marseille's Hospital-University Institute Mediterranean Infection (IHU), who shot to global prominence in the pandemic. French investigations found that he and the IHU had violated ethics-approval protocols in numerous studies, and Raoult has now retired.

The paper, which has received almost 3,400 citations according to the Web of Science database, is the highest-cited paper on COVID-19 to be retracted, and the second-most-cited retracted paper of any kind....

Because it contributed so much to the HCQ hype, "the most important unintended effect of this study was to partially side-track and slow down the development of anti-COVID-19 drugs at a time when the need for effective treatments was critical", says Ole Søgaard, an infectious-disease physician at Aarhus University Hospital in Denmark, who was not involved with the work or its critiques. "The study was clearly hastily conducted and did not adhere to common scientific and ethical standards...."

Three of the study's co-authors had asked to have their names removed from the paper, saying they had doubts about its methods, the retraction notice said.
Nature includes this quote from a scientific-integrity consultant in San Francisco, California. "This paper should never have been published — or it should have been retracted immediately after its publication."

"The report caught the eye of the celebrity doctor Mehmet Oz," the Atlantic reported in April of 2020 (also noting that co-author Raoult "has made news in recent years as a pan-disciplinary provocateur; he has questioned climate change and Darwinian evolution...")

And Nature points out that while the study claimed good results for the 20 patients treated with HCQ, six more HCQ-treated people in the study actually dropped out before it was finished. And of those six people, one died, while three more "were transferred to an intensive-care unit."

Thanks to Slashdot reader backslashdot for sharing the news.

sciencehabit shares a report from Science Magazine: With a few keystrokes, anyone can ask an artificial intelligence (AI) program such as ChatGPT to write them a term paper, a rap song, or a play. But don't expect William Shakespeare's originality. A new study finds such output remains derivative -- at least for now. [...] [O]bjectively testing this creativity has been tricky. Scientists have generally taken two tacks. One is to use another computer program to search for signs of plagiarism -- though a lack of plagiarism does not necessarily equal creativity. The other approach is to have humans judge the AI output themselves, rating factors such as fluency and originality. But that's subjective and time intensive. So Ximing Lu, a computer scientist at the University of Washington, and colleagues created a program featuring both objectivity and a bit of nuance.

Called DJ Search, it collects pieces of text of a minimum length from whatever the AI outputs and searches for them in large online databases. DJ Search doesn't just look for identical matches; it also scans for strings whose words have similar meanings. To evaluate the meaning of a word or phrase, the program itself relies on a separate AI algorithm that produces a set of numbers called an "embedding," which roughly represents the contexts in which words are typically found. Synonymous words have numerically close embeddings. For example, phrases that swap "anticipation" and "excitement" are considered matches. After removing all matches, the program calculates the ratio of the remaining words to the original document length, which should give an estimate of how much of the AI's output is novel. The program conducts this process for various string lengths (the study uses a minimum of five words) and combines the ratios into one index of linguistic novelty. (The team calls it a "creativity index," but creativity requires both novelty and quality -- random gibberish is novel but not creative.)

The researchers compared the linguistic novelty of published novels, poetry, and speeches with works written by recent LLMs. Humans outscored AIs by about 80% in poetry, 100% in novels, and 150% in speeches, the researchers report in a preprint posted on OpenReview and currently under peer review. Although DJ Search was designed for comparing people and machines, it can also be used to compare two or more humanmade works. For example, Suzanne Collins's 2008 novel The Hunger Games scored 35% higher in linguistic originality than Stephenie Meyer's 2005 hit Twilight. (You can try the tool online.)

Axiom Space has revised its plan for assembling its commercial space station by launching the Payload, Power, and Thermal module first, enabling it to operate as a free-flying platform as early as 2028 -- two years ahead of the original timeline. Space.com reports: NASA awarded Axiom Space a contract in 2020 to attach one or more modules to the International Space Station (ISS), which is set to retire by 2030 at the earliest. The original plan called for Axiom to detach a multi-module group from the ISS, creating a commercial outpost in low Earth orbit that will continue operating after the ISS is gone. But that plan has now been altered.

To create its space station, Axiom plans to launch five modules: a payload/power/thermal element, an airlock, a research/manufacturing hub, and a pair of habitat modules. The original plan was for Axiom to launch the Habitat 1 module to the ISS first, followed by the additional elements. The new assembly sequence will see the Payload, Power and Thermal module launch to the ISS first. This module could detach from the station -- and become a free flyer called Axiom Station -- as soon as 2028, according to the company. After that happens, Axiom will continue assembling the outpost, launching the Habitat 1 module to meet up with it. Habitat 1 will be followed by the airlock, the Habitat 2 module, and then the research and manufacturing facility. Angela Hart, a manager for the Commercial Low Earth Orbit Development Program at NASA's Johnson Space Center in Houston, said: "The updated assembly sequence has been coordinated with NASA to support both NASA and Axiom Space needs and plans for a smooth transition in low Earth orbit."

NASA's Parker Solar Probe will make its closest approach yet to the Sun on Christmas Eve, flying within 3.8 million miles of the solar surface and entering its atmosphere for the first time.

The spacecraft, which travels at speeds up to 430,000 miles per hour, aims to study the origins of solar wind -- the stream of charged particles emanating from the Sun's corona. The probe's heat shield will endure temperatures exceeding 2,500-degree Fahrenheit during the flyby, requiring specialized materials like sapphire crystal tubes and niobium wiring to protect its instruments.

Ars Technica's Eric Berger reports: In a wide-ranging interview with a Russian television station, the chief executive of Russia's main space corporation said the country is now planning to participate in the International Space Station project all the way to NASA's desired goal of 2030. "In coordination with our American colleagues, we plan to de-orbit the station sometime around the beginning of 2030," the country's chief space official, Yuri Borisov, said during the interview. "The final scenario will probably be specified after the transition to a new NASA administration."

While the documents for such an extension have not been signed, these comments appear to represent a change in tone from Russia. When he first became head of Roscosmos in 2022, Borisov said Russia would leave the station partnership "after" 2024, which was interpreted as shortly thereafter. Later, Russia committed to working with NASA to keep the orbital outpost flying only through 2028. The US space agency has expressed a consistent desire to keep flying the station until 2030, after which point it hopes that private space station operators can provide one or more replacement facilities.
Borisov said the aging station, elements of which have now been in space for more than a quarter of a century, are becoming difficult to maintain. "Today our cosmonauts have to spend more time repairing equipment and less and less time conducting experiments," he said. Borisov also discussed Russia's challenges of getting private investment in space-related activities, saying: "In the West, particularly in America, 70 percent of space services are provided by satellite constellations created by private companies. This process has only just begun with us. This is a very risky business for potential investors."

"Right now, the dynamic growth of private space is being influenced by the general economic situation (likely referring to Russia's costly war in Ukraine), high inflation and interest rates, which leads to expensive money for private investors. We can hope that this will be a temporary period and more favorable times will come soon."

An anonymous reader quotes an opinion piece from The Guardian, written by Prof Mark Pallen and Dr Aimee Parker (Quadram Institute, Norwich), Prof Nick Loman (University of Birmingham), Prof Alan Walker (University of Aberdeen): Contrary to what is implied in [this article], the weight of expert opinion in medical microbiology rejects the existence of a "brain microbiome" in the sense of a resident microbial community in healthy human brains. While pathogenic microbes -- such as Borrelia burgdorferi, which causes Lyme disease, or fungal pathogens like Cryptococcus neoformans -- can invade the brain and cause neurological symptoms, these are examples of infections, not evidence of a native microbial community.

Similarly, cognitive benefits of vaccines can be explained by their role in preventing infections or modulating immune responses and inflammation, rather than any impact on a "brain microbiome." Furthermore, the studies cited in the article have not undergone independent validation, nor do they provide any kind of consistent picture. This mirrors controversies around other supposed microbiomes -- such as that of the placenta -- which have failed to withstand independent scrutiny. Over a decade of research indicates that contamination, typically from laboratory reagents, is the most plausible explanation for such findings, particularly when even supposedly ultrapure water has been shown to harbor DNA signatures and culturable microbes.

If diverse microbes are truly abundant in the brain, why have they not been repeatedly and consistently cultured in over a century and a half of medical microbiology? Why have they not been observed in numerous microscopy studies of human brain tissue? Efforts to explore overlooked roles of microbes in neurological conditions are welcome, but they must be grounded in robust and reproducible science -- not speculative discussion of a "brain microbiome." In the article mentioned above, author Amy Fleming discusses the emerging research connecting infections such as Borrelia, Cryptococcus, and herpes viruses to reversible dementia, challenging the long-held belief that the brain is sterile.

She highlights the Alzheimer's Pathobiome Initiative, which investigates how brain infections may contribute to diseases like Alzheimer's, with the goal of developing new diagnostic tools and treatments. Vaccines like BCG and zoster have shown protective effects, while good hygiene, oral health, and a healthy lifestyle can help reduce risks.

The publisher of a high-profile, now-corrected study on black plastics has been removed from a critical index of academic journals amid questions about quality criteria, according to a report by Retraction Watch. From a report: On December 16, Clarivate -- a scholarly publication analytics company -- removed the journal Chemosphere from its platform, the Web of Science, which is a key index for academic journals. The indexing platform tracks citations and calculates journal "impact factors," a proxy for relevance in its field. It's a critical metric not only for the journals but for the academic authors of the journal's articles, who use the score in their pursuit of promotions and research funding.

To be included in the Web of Science, Clarivate requires journals to follow editorial quality criteria. According to Retraction Watch, Chemosphere has retracted eight articles this month and published 60 expressions of concern since April. In a December 12 news release, Chemosphere acknowledged the quality concerns and laid out steps it will take to improve its editorial process. Those include improvements to article vetting and peer review, along with assurances that articles will be retracted if there's evidence of policy breaches. "We believe that these measures will help us regain the standard of research integrity that has always been so important to us," the news release stated.

NASA has delayed the launch of SpaceX Crew-10 to late March 2025 to allow time for processing a new Dragon spacecraft, extending the stay of astronauts Butch Wilmore and Suni Williams on the ISS to about nine months. CNN reports: Williams and Wilmore launched to space in June, piloting the first crewed test flight of Boeing's Starliner spacecraft. Their trip, expected to last about a week, ballooned into a monthslong assignment after their vehicle experienced technical issues en route to the space station and NASA determined it would be too risky to bring them home aboard the Starliner.

The astronauts have since joined Crew-9, a routine space station mission originally slated to return to Earth no earlier than February after a handoff period with Crew-10. Now, Crew-10 will get off the ground at least a month later than expected because NASA and SpaceX teams need "time to complete processing on a new Dragon spacecraft for the mission," according to the space agency. "NASA and SpaceX assessed various options for managing the next crewed handover, including using another Dragon spacecraft," NASA noted in a blog post on Tuesday. "After careful consideration, the team determined that launching Crew-10 in late March, following completion of the new Dragon spacecraft, was the best option for meeting NASA's requirements and achieving space station objectives for 2025."

The CDC has confirmed the first case of severe bird flu in the United States. NPR reports: Louisiana health officials initially reported the infection last week, saying a person was hospitalized after being exposed to sick and dead birds in backyard flocks. On Wednesday, the Centers for Disease Control and Prevention shared their findings that indicate the H5N1 virus responsible for the illness belongs to a genetic lineage that's circulating in wild birds and poultry -- different from what's spreading in dairy cattle and driving the majority of infections in agricultural workers.

In the U.S., more than 60 people have been infected so far, although some research suggests the official tally may be an undercount. The illnesses linked to dairy cattle have largely led to mild illnesses in humans.

The version of the virus in the Louisiana case is the so-called "D1.1 genotype." It has previously popped up in poultry workers in Washington state, who developed mild symptoms after testing positive in October. More recently, however, a teenager in British Columbia was hospitalized after contracting this D1.1 strain of the virus. Canadian health officials were unable to figure out how that person was infected. Dr. Demetre Daskalakis with the CDC, told reporters on Wednesday that bird blu has a well-established history of leading to severe illness and death. He added: "Infections without a clear source of exposure do occur, neither these cases nor the cases with known animal or animal products exposure have resulted in human to human transmission." California Gov. Gavin Newsom declared a state of emergency as the H5N1 bird flu virus moves from the Central valley to Southern California herds. The declaration will allow for a more streamlined approach among state and local agencies to tackle the virus, providing "flexibility around staffing, contracting, and other rules to support California's evolving response,'" reports the Los Angeles Times, citing a statement from Newsom's office.

"Building on California's testing and monitoring system -- the largest in the nation -- we are committed to further protecting public health, supporting our agriculture industry, and ensuring that Californians have access to accurate, up-to-date information," said Newsom in a statement. "While the risk to the public remains low, we will continue to take all necessary steps to prevent the spread of this virus."

Further reading:
US Government Orders Nationwide Testing of Milk for Bird Flu to Stop the Virus's Spread
Bird Flu Fears Stoke the Race for an mRNA Flu Vaccine

Scripps Research scientists sent stem-cell-derived brain organoids to the ISS to study the effects of microgravity on brain cells, finding that the organoids matured faster and showed signs of specialization compared to Earth-grown controls. The findings have been published in the journal Stem Cells Translational Medicine. Phys.Org reports: To examine how the space environment impacts cellular functions, the team compared the cells' RNA expression patterns -- a measure of gene activity -- to identical "ground control" organoids that had remained on Earth. Surprisingly, they found that the organoids grown in microgravity had higher levels of genes associated with maturity and lower levels of genes associated with proliferation compared to the ground controls, meaning that the cells exposed to microgravity developed faster and replicated less than those on Earth. "We discovered that in both types of organoids, the gene expression profile was characteristic of an older stage of development than the ones that were on the ground," [says co-senior author Jeanne Loring, Ph.D., professor emeritus in the Department of Molecular Medicine and founding director of the Center for Regenerative Medicine at Scripps Research]. "In microgravity, they developed faster, but it's really important to know these were not adult neurons, so this doesn't tell us anything about aging."

The team also noted that contrary to their hypothesis, there was less inflammation and lower expression of stress-related genes in organoids grown in microgravity, but more research is needed to determine why. Loring speculates that microgravity conditions may more closely mirror the conditions experienced by cells within the brain compared to organoids grown under conventional lab conditions and in the presence of gravity. "The characteristics of microgravity are probably also at work in people's brains, because there's no convection in microgravity -- in other words, things don't move," says Loring. "I think that in space, these organoids are more like the brain because they're not getting flushed with a whole bunch of culture medium or oxygen. They're very independent; they form something like a brainlet, a microcosm of the brain." "The next thing we plan to do is to study the part of the brain that's most affected by Alzheimer's disease," says Loring. "We also want to know whether there are differences in the way neurons connect with each other in space. With these kinds of studies, you can't rely on earlier work to predict what the result would be because there is no earlier work. We're on the ground floor, so to speak; in the sky, but on the ground floor."

SpaceX has filed a petition to incorporate its Starbase facility in South Texas as a new city, aiming to streamline infrastructure development and support the growing workforce needed for Starship production and testing. Space.com reports: "To continue growing the workforce necessary to rapidly develop and manufacture Starship, we need the ability to grow Starbase as a community," SpaceX said in the petition, which was shared in a post on X (formally Twitter). "That is why we are requesting that Cameron County call an election to enable the incorporation of Starbase as the newest city in the Rio Grande Valley."

The petition was addressed to Cameron County Judge Eddie Trevino Jr., the county's top elected official. The next step will be for officials to review the petition to determine if it complies with statutory requirements. Then, an election would be held to incorporate Starbase. [...] With Starship expected to "fundamentally alter humanity's access to space," SpaceX aims to make the area of the Starbase launch site the "Gateway to Mars," the company wrote in the petition. [...] "Incorporating Starbase will streamline the processes required to build the amenities necessary to make the area a world class place to live -- for hundreds already calling it home, as well as for prospective workers eager to help build humanity's future in space," SpaceX officials said in the petition.

An Alabama woman became the third person to receive a pig kidney transplant, doctors at NYU Langone Health announced Tuesday. Towana Looney, 53, underwent the procedure on November 25 and was discharged December 6.

Her kidney came from a pig with 10 genetic modifications designed to prevent organ rejection. The surgery follows two previous pig kidney transplants this year -- Richard Slayman at Massachusetts General Hospital, who died two months post-surgery from cardiac complications, and Lisa Pisano at NYU Langone, whose transplanted kidney was removed after 47 days due to blood flow issues.

Ars Technica's Beth Mole reports: Editors of the environmental chemistry journal Chemosphere have posted an eye-catching correction to a study reporting toxic flame retardants from electronics wind up in some household products made of black plastic, including kitchen utensils. The study sparked a flurry of media reports a few weeks ago that urgently implored people to ditch their kitchen spatulas and spoons. Wirecutter even offered a buying guide for what to replace them with. The correction, posted Sunday, will likely take some heat off the beleaguered utensils. The authors made a math error that put the estimated risk from kitchen utensils off by an order of magnitude.

Specifically, the authors estimated that if a kitchen utensil contained middling levels of a key toxic flame retardant (BDE-209), the utensil would transfer 34,700 nanograms of the contaminant a day based on regular use while cooking and serving hot food. The authors then compared that estimate to a reference level of BDE-209 considered safe by the Environmental Protection Agency. The EPA's safe level is 7,000 ng -- per kilogram of body weight -- per day, and the authors used 60 kg as the adult weight (about 132 pounds) for their estimate. So, the safe EPA limit would be 7,000 multiplied by 60, yielding 420,000 ng per day. That's 12 times more than the estimated exposure of 34,700 ng per day. However, the authors missed a zero and reported the EPA's safe limit as 42,000 ng per day for a 60 kg adult. The error made it seem like the estimated exposure was nearly at the safe limit, even though it was actually less than a tenth of the limit. "We regret this error and have updated it in our manuscript," the authors said in a correction.

"This calculation error does not affect the overall conclusion of the paper," the correction reads. The study maintains that flame retardants "significantly contaminate" the plastic products, which have "high exposure potential."

Does space need environmentalists, asks the headline from a new article in Noema magazine. "As astrophysicist Neil deGrasse Tyson notes, the first trillionaire will be made in space.

"But amid such promising developments are worries among some scientists and environmentalists who fear humans will repeat the errors that resource extraction has wrought on Earth..." If we have mining in space, do we need a preemptive anti-mining campaign to protect our solar system from rampant exploitation before it is too late? Earth-bound environmental advocates and astrobiologists alike have concluded that, indeed, we need an environmental movement in space... [Daniel Capper, an adjunct professor of philosophy at the Metropolitan State University of Denver] is part of a small but growing chorus of intellectuals who argue that we must carve out protections sooner rather than later — backed by a concrete theoretical and legal framework — for certain areas of the solar system. The United Nations has convened a working group on the use of space resources, and the International Astronomical Union has set up a different working group to delineate places of special scientific value on the moon.

Some researchers have proposed creating a planetary park system in space, while others advocate for a circular space economy that minimizes the need for additional resources. The nonprofit For All Moonkind is advocating for the protection of space sites of cultural importance, like the Apollo 11 landing site. And the Astra Carta, backed by Britain's King Charles, advocates for making sustainability a key component of space activities... [Martin Elvis, an astronomer with the Center for Astrophysics at Harvard University and the Smithsonian Institution] proposed setting aside 7/8ths of the solar system as wilderness, in a paper published in 2019 in Acta Astronautica that he coauthored with King's College London philosopher Tony Milligan...

[T]he lack of norms — clear rules and regulations around space — is one of the most pressing threats to the space environment, advocates say. What might happen, for example, if the United States simply began scooping up asteroids for platinum, or if Blue Origin established a mine at the lunar South Pole without securing consensus from others? "We do not have good answers to those questions right now," Hanlon said. "This is something that I'm really concerned about." Much of the legal basis for the space environmentalism movement is currently contained in just one article of the Outer Space Treaty (OST), said Christopher Johnson, the director of legal affairs and space law at the Secure World Foundation. Article 9 of the OST contains the harmful contamination language and says actors must pay "due regard" to the interests of others. It also stipulates that "harmful interference" with the activities of others must be avoided. Those phrases could be interpreted in multiple ways and have yet to be meaningfully tested.
The article cites two concrete proposals moving forward:

• "The Artemis Accords, a set of principles for exploring and using resources in outer space established by the U.S. in 2020, argues that resource extraction does not constitute national appropriation, and is therefore allowed by the OST. It's an initial step toward securing a consensus on space regulations, and one that's to date received the signatures of 47 nations including Japan, the United Kingdom, France and Germany (though China and Russia are notably absent). Signing the Artemis Accords allows nations to participate in the Artemis program, and also play a role in shaping future norms in space, Johnson said, a potentially lucrative incentive... "

• "The UN's COPUOS, the same one responsible for the OST and the Moon Agreement, published a working paper in 2019 that laid out voluntary guidelines for the long-term sustainability of outer space activities. Recommendations from the committee's working group on principles for the use of space resources are due in 2027, and Johnson said draft guidelines are likely to emerge in early 2025."

"One day, our descendants might live among the stars," the article concludes. "But we must ask ourselves, what kind of place will they inherit?"

Researchers used Canada's national synchrotron light source facility "to analyze a new type of lithium-ion battery material — called a single-crystal electrode — that's been charging and discharging non-stop in a Halifax lab for more than six years," reports Tech Xplore.

The results? The battery material "lasted more than 20,000 cycles before it hit the 80% capacity cutoff," which they say is equivalent to driving 8 million kms (nearly 5 million miles). That's more than eight times the life of a regular lithium-ion battery that lasted 2,400 cycles before reaching the 80% cutoff — and "When the researchers looked at the single crystal electrode battery, they saw next to no evidence of this mechanical stress." (One says the material "looked very much like a brand-new cell." Toby Bond [a senior scientist at the CLS, who conducted the research for his Ph.D.] attributes the near absence of degradation in the new style battery to the difference in the shape and behavior of the particles that make up the battery electrodes... The single crystal is, as its name implies, one big crystal: it's more like an ice cube. "If you have a snowball in one hand, and an ice cube in the other, it's a lot easier to crush the snowball," says Bond. "The ice cube is much more resistant to mechanical stress and strain." While researchers have for some time known that this new battery type resists the micro cracking that lithium-ion batteries are so susceptible to, this is the first time anyone has studied a cell that's been cycled for so long...

Bond says what's most exciting about the research is that it suggests we may be near the point where the battery is no longer the limiting component in an EV — as it may outlast the other parts of the car. The new batteries are already being produced commercially, says Bond, and their use should ramp up significantly within the next couple of years. "I think work like this just helps underscore how reliable they are, and it should help companies that are manufacturing and using these batteries to plan for the long term."
Thanks to long-time Slashdot reader schwit1 for sharing the news.