Medicine

Massive Recall of Homeopathic Kids' Products Spotlights Dubious Health Claims (arstechnica.com) 119

Earlier this week, the Food and Drug Administration (FDA) issued a statement that the homeopathic drug company King Bio is recalling 32 of its children's pain-relievers. According to the FDA, a "small percentage" of those products tested positive for bacterial contamination during regular, random testing by King Bio. From a report: The announcement does not provide any specifics about the contamination or potential risks. However, the North Carolina-based manufacturer behind the recall, King Bio, issued a similar announcement back in July. At that time, the company recalled three other products after an FDA inspection found batches contaminated with the bacteria Pseudomonas brenneri, Pseudomonas fluorescens, and Burkholderia multivorans. Pseudomonas brenneri is a bacterium recently found in natural mineral waters, and its clinical significance is murky. However, Pseudomonas fluorescens is known to be an opportunistic pathogen, causing blood infections, and Burkholderia multivorans can cause infections in people with compromised immune systems and cystic fibrosis. It was also recently found to be a rare but emerging cause of meningitis. King Bio did not respond to Ars' request for comment on the contamination, its potential source, or the company's actions to prevent further contamination.

Homeopathic products, as Ars readers are likely familiar, are those based on a pseudoscientific belief that substances generating similar symptoms to an ailment can cure that ailment, aka the "law of similars." The potentially dangerous substances are generally safe to consume because homeopaths believe that "vigorous shaking" and excessive dilution -- often to the point where no atoms of the original substance remain -- make them more effective. As King Bio puts it, this preparation "potentizes" the substances.
King Bio told the FDA that the items of concern were a group of various over-the-counter remedies produced between August 1, 2017 and April 2018.
Science

Scientists Deliver a Longer-Lasting Lithium-Oxygen Battery (technologyreview.com) 82

Packing more energy into batteries is the key to delivering electric cars with longer range, smartphones that can last days -- and cheaper electronic products all around. Lithium-oxygen batteries represent one of the more promising paths toward that end. From a report: They could boost energy density by an order of magnitude above conventional lithium-ion batteries -- in theory, at least. In a paper published this week in Science journal, researchers at the University of Waterloo identified ways of addressing some of the major hurdles to converting that potential into commercial reality.

A critical problem has been that as a lithium-oxygen battery discharges, oxygen is converted into superoxide and then lithium peroxide, reactive compounds that corrode the battery's components over time. That, in turn, limits its recharging ability -- and any real-world utility. To get around the problem, researchers switched from a carbon cathode to one made of nickel oxide and supported by a stainless steel mesh. They also used molten salt for the electrolyte -- the part of the battery that allows positively charged ions to move between the electrodes -- and raised the battery's operating temperature to 150C. Those steps made it possible to achieve about three times the number of charging cycles as earlier lithium-oxygen efforts. The researchers also managed to increase the energy per unit of mass by more than 50 percent.

Beer

No Healthy Level of Alcohol Consumption, Says Major Study (theguardian.com) 590

An anonymous reader quotes a report from The Guardian: Even the occasional drink is harmful to health, according to the largest and most detailed research carried out on the effects of alcohol, which suggests governments should think of advising people to abstain completely. The uncompromising message comes from the authors of the Global Burden of Diseases study, a rolling project based at the University of Washington, in Seattle, which produces the most comprehensive data on the causes of illness and death in the world. Alcohol, says their report published in the Lancet medical journal, led to 2.8 million deaths in 2016. It was the leading risk factor for premature mortality and disability in the 15 to 49 age group, accounting for 20% of deaths. The study was carried out by researchers at the Institute of Health Metrics and Evaluation (IHME), who investigated levels of alcohol consumption and health effects in 195 countries between 1990 to 2016. They used data from 694 studies to work out how common drinking was and from 592 studies including 28 million people worldwide to work out the health risks. According to the report, "27.1% of cancer deaths in women and 18.9% in men over 50 were linked to their drinking habits." The biggest causes of death linked to alcohol in younger people were tuberculosis (1.4% of deaths), road injuries (1.2%), and self-harm (1.1%).

"Worldwide we need to revisit alcohol control policies and health programs, and to consider recommendations for abstaining from alcohol," said the report's senior author, Professor Emmanuela Gakidou. "These include excise taxes on alcohol, controlling the physical availability of alcohol and the hours of sale, and controlling alcohol advertising. Any of these policy actions would contribute to reductions in population-level consumption, a vital step toward decreasing the health loss associated with alcohol use."
NASA

VP Pence Talks Moon Return and Mars Mission at NASA 146

Vice President Mike Pence spoke at NASA's Johnson Space Center on Thursday about the agency's plans to send humans back to the moon for the first time in almost half a century and eventually on to Mars. He said: The next Americans who set foot on the Moon will start their journey by stepping through the NASA's Orion hatch. And this extraordinary spacecraft will one day bridge the gap between our planet and the next.

The International Space Station has been an unqualified success. Soon and very soon American astronauts will return to space on American rockets launched from American soil. America will not ever abandon the critical domain of space, we will open the way for innovators and development and we will lead once again in human exploration. Our administration is working tirelessly to put an American crew aboard the lunar orbital platform before the end of 2024.
In a prepared statement, Pence added, "We're renewing our national commitment to discovery and exploration and write the next great chapter of our nation's journey into space. It's now the official policy of the US that we'll return to the Moon, put Americans on Mars and once again explore the farthest depths of outer space."
Earth

New Research Suggests Evolution Might Favor 'Survival of the Laziest' (phys.org) 153

Zorro shares a report from Phys.org: If you've got an unemployed, 30-year-old adult child still living in the basement, fear not. A new large-data study of fossil and extant bivalves and gastropods in the Atlantic Ocean suggests laziness might be a fruitful strategy for survival of individuals, species and even communities of species. The results have just been published in the Proceedings of the Royal Society B by a research team based at the University of Kansas. Looking at a period of roughly 5 million years from the mid-Pliocene to the present, the researchers analyzed 299 species' metabolic rates -- or, the amount of energy the organisms need to live their daily lives -- and found higher metabolic rates were a reliable predictor of extinction likelihood. "We wondered, 'Could you look at the probability of extinction of a species based on energy uptake by an organism?'" said Luke Strotz, postdoctoral researcher at KU's Biodiversity Institute and Natural History Museum and lead author of the paper. "We found a difference for mollusk species that have gone extinct over the past 5 million years and ones that are still around today. Those that have gone extinct tend to have higher metabolic rates than those that are still living. Those that have lower energy maintenance requirements seem more likely to survive than those organisms with higher metabolic rates."

Strotz' co-author Bruce Lieberman added: "Maybe in the long term the best evolutionary strategy for animals is to be lassitudinous and sluggish -- the lower the metabolic rate, the more likely the species you belong to will survive. Instead of 'survival of the fittest,' maybe a better metaphor for the history of life is 'survival of the laziest' or at least 'survival of the sluggish.'"
Medicine

Poor Sleep Alters Metabolism and Boosts Body's Ability To Store Fat, Study Finds (theguardian.com) 233

An anonymous reader quotes a report from The Guardian: The latest study provides new evidence that sleep deprivation has a direct influence on basic metabolism and the body's balance between fat and muscle mass. In the study, published in the journal Science Advances, 15 healthy volunteers each attended a testing session on two occasions, once after a normal night's sleep and once after staying up all night. During the visit, they gave samples of fat and muscle tissue and blood. After sleep deprivation, people's fat tissue showed changes in gene activity that are linked to cells increasing their tendency to absorb lipids and also to proliferate.

By contrast, in muscle the scientists saw reduced levels of structural proteins, which are the building blocks the body requires to maintain and build muscle mass. Previous epidemiological studies have also found shift workers and those who sleep less have lower muscle mass. This may be in part down to lifestyle factors, but the latest work shows that there are also fundamental biological mechanisms at play. The study also found an increase in inflammation in the body after sleep deprivation, which is a known risk factor for type 2 diabetes.

Facebook

Facebook Wants To Use Machine Learning To Make MRIs Faster 67

Facebook believes they can use machine learning to speed up magnetic resonance imaging (MRI) scans. Computer scientists from the social networking site are working with New York University's medical school on the project. CNNMoney reports: NYU is providing an anonymous dataset of 10,000 MRI exams, a trove that will include as many as three million images of knees, brains and livers. Researchers will use the data to train an algorithm, using a method called deep learning, to recognize the arrangement of bones, muscles, ligaments, and other things that make up the human body. Building this knowledge into the software that powers an MRI machine will allow the AI to create a portion of the image, saving time. Making the tests faster would allow radiologists to perform a wider variety of tests.
NASA

NASA Supports SpaceX Plan To Fuel Rockets With Astronauts On Board (engadget.com) 165

For years, NASA has been debating whether to allow SpaceX to fuel its spacecraft with super-cold propellant after astronauts have boarded. While the company typically fuels its rockets shortly before launch in order to prevent the coolant from warming up too much, the practice has been deemed "a potential safety risk" by NASA safety advisers due to the high risk of an explosion. Now, according to Engadget, NASA has "decided that it will move forward with the SpaceX plan to fuel rockets after astronauts have already boarded." From the report: "To make this decision, our teams conducted an extensive review of the SpaceX ground operations, launch vehicle design, escape systems and operational history," Kathy Lueders, manager of NASA's Commercial Crew Program, said in a statement. "Safety for our personnel was the driver for this analysis, and the team's assessment was that this plan presents the least risk." SpaceX will have to prove its system is safe, however. The company will have to demonstrate the fueling procedure five times prior to its first crewed flight and afterwards, NASA will assess any remaining risk before certifying SpaceX's system. In September 2016, a Falcon 9 rocket exploded on the launchpad while it was being loaded with propellant. No injuries were reported, but it didn't look good to NASA which was already reviewing the fueling procedure.
Earth

Tiny Plastic Is Everywhere (npr.org) 210

An anonymous reader shares a report from NPR about ecologist Chelsea Rochman, who has dedicated her career to studying how microplastics are getting into the food chain and affecting everything from beer to fish: Since modern plastic was first mass-produced, 8 billion tons have been manufactured. And when it's thrown away, it doesn't just disappear. Much of it crumbles into small pieces. Scientists call the tiny pieces "microplastics" and define them as objects smaller than 5 millimeters -- about the size of one of the letters on a computer keyboard. Researchers started to pay serious attention to microplastics in the environment about 15 years ago. They're in oceans, rivers and lakes. They're also in soil. Recent research in Germany found that fertilizer made from composted household waste contains microplastics. And, even more concerning, microplastics are in drinking water. In beer. In sea salt. In fish and shellfish. How microplastics get into animals is something of a mystery, and Chelsea Rochman is trying to solve it.

Since she started studying microplastics, Rochman has found them in the outflow from sewage treatment plants. And they've shown up in insects, worms, clams, fish and birds. To study how that happens, [researcher Kennedy Bucci] makes her own microplastics from the morning's collection. She takes a postage stamp-size piece of black plastic from the jar, and grinds it into particles using a coffee grinder. "So this is the plastic that I feed to the fish," she says. The plastic particles go into beakers of water containing fish larvae from fathead minnows, the test-animals of choice in marine toxicology. Tanks full of them line the walls of the lab. Bucci uses a pipette to draw out a bunch of larvae that have already been exposed to these ground-up plastic particles. The larva's gut is translucent. We can see right into it. "You can see kind of a line of black, weirdly shaped black things," she points out. "Those are the microplastics." The larva has ingested them. Rochman says microplastic particles can sicken or even kill larvae and fish in their experiments.

Earth

Summer Weather Is Getting 'Stuck' Due To Arctic Warming (theguardian.com) 387

An anonymous reader quotes a report from The Guardian: Summer weather patterns are increasingly likely to stall in Europe, North America and parts of Asia, according to a new climate study that explains why Arctic warming is making heatwaves elsewhere more persistent and dangerous. Rising temperatures in the Arctic have slowed the circulation of the jet stream and other giant planetary winds, says the paper, which means high and low pressure fronts are getting stuck and weather is less able to moderate itself. The authors of the research, published in Nature Communications on Monday, warn this could lead to "very extreme extremes," which occur when abnormally high temperatures linger for an unusually prolonged period, turning sunny days into heat waves, tinder-dry conditions into wildfires, and rains into floods.

One cause is a weakening of the temperature gradient between the Arctic and Equator as a result of man-made greenhouse gas emissions. The far north of the Earth is warming two to four times faster than the global average, says the paper, which means there is a declining temperature gap with the central belt of the planet. As this ramp flattens, winds struggle to build up sufficient energy and speed to push around pressure systems in the area between them. As a result, there is less relief in the form of mild and wet air from the sea when temperatures accumulate on land, and less relief from the land when storms build up in the ocean.

Moon

Scientists Find Direct Evidence of Ice On the Moon (qz.com) 16

According to a new study, published today in the Proceedings of the National Academy of Sciences, scientists have found the first direct evidence of frozen water on the Moon's poles. "The discovery is based on data gathered by the Moon Mineralogy Mapper, a NASA instrument that flew to the Moon back in 2008," reports Quartz. From the report: Reanalyzing this data today, the researchers found tiny patches of ice mixed with rock on the surface of certain craters at the northernmost and southernmost points on the Moon. Shuai Li, a geologist at the University of Hawaii who worked on the study, says the data can't tell us where the ice originally came from. However, Li adds, it's likely that it came from comets that smashed into the Moon years ago. Collisions with other space objects, like meteorites and comets, gave the Moon its pockmarked surface, and could have easily brought a foreign substance like ice along with them. Ice on the lunar surface could also be a result of gases coming out of the rock below. It could also be due to solar winds -- energetically charged ions emanating from the sun -- bombarding the Moon's surface to cause the chemical reactions needed to make frozen water. However, to truly understand the ice's origins, Li hopes to get a rover onto the Moon to take actual samples of the frigid lunar ground and its ice.
Earth

Construction Begins On $1 Billion Telescope That Will Take Pictures 10 Times Sharper Than Hubble's (qz.com) 97

The $1 billion Giant Magellan Telescope in Chile is officially under construction with a scheduled date of operation in 2024. The telescope "will have an array of seven enormous mirrors totaling 80 feet in diameter, giving it 10 times the precision of the Hubble telescope," reports Quartz. "Among its advances is technology to help it correct for the distorting effect of Earth's atmosphere by using software to make hundreds of adjustments per second to its array of secondary mirrors." From the report: The project's architects, a consortium of universities and institutions in the U.S., Korea, and Australia, chose to build in Chile's Atacama desert for its clear, dry skies. Astronomers will use the Magellan Telescope to study the origins of elements and the birth of stars and galaxies, and to examine planets that have been identified as potentially harboring life. Mother Nature Network has an article highlighting nine of the largest new telescopes expected to begin operation in the next decade.
Medicine

Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (nytimes.com) 151

The New York Times tells the story of Dr. Michael Holick, a Boston University endocrinologist "who perhaps more than anyone else is responsible for creating a billion-dollar vitamin D sales and testing juggernaut." From the report: Dr. Holick's role in drafting national vitamin D guidelines, and the embrace of his message by mainstream doctors and wellness gurus alike, have helped push supplement sales to $936 million in 2017. That's a ninefold increase over the previous decade. Lab tests for vitamin D deficiency have spiked, too: Doctors ordered more than 10 million for Medicare patients in 2016, up 547 percent since 2007, at a cost of $365 million. But few of the Americans swept up in the vitamin D craze are likely aware that the industry has sent a lot of money Dr. Holick's way. A Kaiser Health News investigation for The New York Times found that he has used his prominent position in the medical community to promote practices that financially benefit corporations that have given him hundreds of thousands of dollars -- including drug makers, the indoor tanning industry and one of the country's largest commercial labs.

In an interview, Dr. Holick acknowledged he has worked as a consultant to Quest Diagnostics, which performs vitamin D tests, since 1979. Dr. Holick, 72, said that industry funding "doesn't influence me in terms of talking about the health benefits of vitamin D." There is no question that the hormone is important. Without enough of it, bones can become thin, brittle and misshapen, causing a condition called rickets in children and osteomalacia in adults. The issue is how much vitamin D is healthy, and what level constitutes deficiency.

Communications

Two Months Later: NASA's Opportunity Rover Is Still Lost On Mars After Huge Dust Storm (space.com) 46

Two months have passed since NASA's Opportunity Mars rover last phoned home. The last time we reported on the rover was on June 12th, when it was trying to survive an intensifying dust storm that was deemed "much worse than a 2007 storm that Opportunity weathered," according to NASA. "The previous storm had an opacity level, or tau, somewhere above 5.5; this new storm had an estimated tau of 10.8." Space.com reports on Opportunity's current status: Opportunity hasn't made a peep since June 10, when dust in the Red Planet's air got so thick that the solar-powered rover couldn't recharge its batteries. Opportunity's handlers think the six-wheeled robot has put itself into a sort of hibernation, and they still hope to get a ping once the dust storm has petered out. And there are good reasons for this optimism, NASA officials said. "Because the batteries were in relatively good health before the storm, there's not likely to be too much degradation," NASA officials wrote in an Opportunity update Thursday (Aug. 16). "And because dust storms tend to warm the environment -- and the 2018 storm happened as Opportunity's location on Mars entered summer -- the rover should have stayed warm enough to survive."

Engineers are trying to communicate with Opportunity several times a week using NASA's Deep Space Network, a system of big radio dishes around the globe. They hail the robot during scheduled "wake-up times" and then listen for a response. And team members are casting a wider net, too: Every day, they sift through all radio signals received from Mars, listening for any chirp from Opportunity, NASA officials said. Even if Opportunity does eventually wake up and re-establish contact, its long ordeal may end up taking a toll on the rover.
"The rover's batteries could have discharged so much power -- and stayed inactive so long -- that their capacity is reduced," NASA officials wrote in the update. "If those batteries can't hold as much charge, it could affect the rover's continued operations. It could also mean that energy-draining behavior, like running its heaters during winter, could cause the batteries to brown out."
Medicine

Low-Carb Diets Could Shorten Life, Study Suggests (bbc.com) 170

An anonymous reader quotes a report from the BBC: In the study, published in The Lancet Public Health, 15,400 people from the U.S. filled out questionnaires on the food and drink they consumed, along with portion sizes. From this, scientists estimated the proportion of calories they got from carbohydrates, fats, and protein. After following the group for an average of 25 years, researchers found that those who got 50-55% of their energy from carbohydrates (the moderate carb group) had a slightly lower risk of death compared with the low and high-carb groups. Researchers estimated that, from the age of 50, people in the moderate carb group were on average expected to live for another 33 years. This was: four years more than people who got 30% or less of their energy from carbs (extra-low-carb group); 2.3 years more than the 30%-40% (low-carb) group; and 1.1 years more than the 65% or more (high-carb) group.

The scientists then compared low-carb diets rich in animal proteins and fats with those that contained lots of plant-based protein and fat. They found that eating more beef, lamb, pork, chicken and cheese in place of carbs was linked with a slightly increased risk of death. But replacing carbohydrates with more plant-based proteins and fats, such as legumes and nuts, was actually found to slightly reduce the risk of mortality.

Cellphones

Science Confirms That Women's Pockets Suck For Smartphones (theverge.com) 277

It's a well-documented, often criticized phenomenon that women's pockets are too small to fit a smartphone, but "there's been very little data to back up a wealth of anecdotal evidence," writes Megan Farokhmanesh via The Verge. Now, The Pudding has used scientific findings to fill this absence. From the report: According to The Pudding's findings, pockets in women's jeans are, on average, 48 percent shorter and 6.5 percent narrower than those of men's. To put this into a perspective we all care about, the site says that only 40 percent of women's front pockets can completely fit a iPhone X. The number only goes down for the Samsung Galaxy or Google Pixel (20 percent and 5 percent, respectively, though the report doesn't specify which model) of the flagships). As for men's pockets? The Pudding marks a 100 percent success rate for the iPhone X, 95 percent for the Samsung Galaxy, and 85 percent for the Google Pixel. "If you're thinking 'But men are bigger than women,' then sure, on average that's true," the site adds. "But here we measured 80 pairs of jeans that all boasted a 32 inch waistband, meaning that these jeans were all made to fit the same size person."
Biotech

This Company Embeds Microchips in Its Employees, and They Love It (technologyreview.com) 250

Last August, 50 employees at Three Square Market got RFID chips in their hands. Now 80 have them. From a report: The idea came about in early 2017, president of Three Square Market Patrick McMullan says, when he was on a business trip to Sweden -- a country where some people are getting subcutaneous microchips to do things like enter secure buildings or book train tickets. It's one of very few places where chip implants, which have been around for quite a while, have taken off in some fashion. The chips he and his employees got are about the size of a very large grain of rice. They're intended to make it a little easier to do things like get into the office, log on to computers, and buy food and drinks in the company cafeteria. Like many RFID chips, they are passive -- they don't have batteries, and instead get their power from an RFID reader when it requests data from the chip.

A year into their experiment, McMullan and a few employees say they are still using the chips regularly at work for all the activities they started out with last summer. Since then, an additional 30 employees have gotten the chips, which means that roughly 80 of the company's now 250 employees, or nearly a third, are walking, talking cyborgs. "You get used to it; it's easy," McMullan says. As far as he knows, just two Three Square Market employees have had their chips removed -- and that was when they left the company.

Medicine

The Psychedelic Drug DMT Can Simulate a Near-Death Experience, Study Suggests (vice.com) 120

dmoberhaus writes: In the first study of its kind, [published this week in the journal Frontiers in Psychology,] researchers dosed 13 people with the potent psychedelic dimethyltryptamine (DMT) to investigate its similarity to near-death experiences. As the researchers found, DMT does in fact induce experiences that are qualitatively similar to NDEs, [but the intensity of these NDEs largely depend on context]. Motherboard spoke with an independent researcher who pioneered DMT research in the 90s to discuss the possible implications of this research. While tricky to define due to their subjective nature, "NDEs tend to share many common elements, such as feelings of inner peace, the experience of traveling through a tunnel, out of body experiences, and encounters with sentient beings," reports Motherboard. A psychiatrist not involved with the study "suggested that the overlap between DMT and NDEs could possibly be explained on a biological level since DMT is naturally produced in small quantities by the human body and has been shown to minimize neuronal damage due to hypoxia (insufficient oxygen) in test tubes," reports Motherboard. "Thus, [the psychiatrist said] 'one could construct a coherent scenario where endogenous DMT rises in response to cardiac arrest/hypoxia in order to protect the brain as long as possible.'"
Medicine

FDA Approves First Generic Version of EpiPen (go.com) 136

An anonymous reader quotes a report from ABC News: The U.S. Food and Drug Administration has approved the first generic version of the EpiPen and EpiPen Jr auto injector for the emergency treatment of allergic reactions. The approval is part of the FDA's "longstanding commitment" to providing access to low-cost generic alternatives, FDA Commissioner Scott Gottlieb said in a statement. It is unclear how much the generic product -- manufactured by Teva Pharmaceuticals -- will cost. In August 2016, Mylan Pharmaceuticals was criticized for raising the price of a two-pack of EpiPens to $600. The price of two EpiPens was about $100 in 2009. The brand name version is by far the most popular epinephrine auto-injector on the market. "This approval means patients living with severe allergies who require constant access to life-saving epinephrine should have a lower-cost option, as well as another approved product to help protect against potential drug shortages," said FDA Commissioner Scott Gottlieb in a statement.
Science

A Paper Posted Last Month Claims To Have Achieved Superconductivity at Room Temperature, But Other Physicists Say the Data May Be Incorrect (vice.com) 163

dmoberhaus writes: Last month, two Indian physicists posted a paper to arxiv claiming to have demonstrated superconductivity at room temperature. If this paper is legitimate, it would represent a breakthrough in a problem that has existed for superconductivity for 100 years. Understandably, the paper shook the physics world, but when researchers started digging into the data they noticed something wasn't quite right -- the noise patterns in two independent measurements exactly correlated, which is basically impossible in a random system. The Indian researchers have doubled down on their data, and things only got weirder from there. This is a look inside what could be the biggest drama to happen in physics in nearly a decade.

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